针灸治疗化疗所致癌因性疲乏的疗效与安全性：一项系统综述
The Efficacy and Safety of Acupuncture in Treating Cancer-Related Fatigue Caused by Chemotherapy: A Systematic Review
DOI: 10.12677/acm.2025.15102840, PDF,   
作者: 马 丹：黑龙江中医药大学研究生院，黑龙江 哈尔滨；孙晓伟*：黑龙江中医药大学附属第一医院康复二科，黑龙江 哈尔滨
关键词: 针灸；癌因性疲乏；化疗；疗效；安全性；Acupuncture； Cancer-Related Fatigue； Chemotherapy； Therapeutic Effect； Safety
摘要: 癌因性疲乏(CRF)是恶性肿瘤患者化疗期间常见的主观症状，发生率高且严重影响生活质量及治疗依从性。目前西医缺乏特效疗法，常规支持治疗效果有限。针灸作为中医重要治法，凭借其整体调节和操作简便、安全性高等优势，已成为CRF管理的研究热点。本文系统综述针灸治疗化疗所致CRF的疗效与安全性，涵盖针刺、艾灸、穴位贴敷及联合疗法等多种干预方式。结果表明，针灸可显著改善患者疲乏程度、免疫功能及生活质量，其机制涉及调节炎症因子、神经内分泌功能及能量代谢等多途径。安全性方面，针灸仅引起轻微短暂不良反应，无严重事件报告，具备良好风险效益比。本综述旨在为针灸治疗CRF提供循证依据，推动其在中西医结合肿瘤康复中的规范应用与个体化发展。
Abstract: Cancer-related fatigue (CRF) is a common subjective symptom among patients with malignant tumors during chemotherapy, with a high incidence rate and a significant impact on quality of life and treatment compliance. Currently, Western medicine lacks specific and effective therapies, and the effects of conventional supportive treatments are limited. Acupuncture, as an important treatment method in traditional Chinese medicine, has become a research hotspot in the management of CRF due to its advantages of overall regulation, simplicity of operation, and high safety. This article systematically reviews the efficacy and safety of acupuncture in treating CRF caused by chemotherapy, covering various intervention methods such as acupuncture, moxibustion, acupoint application, and combined therapies. The results show that acupuncture can significantly improve the degree of fatigue, immune function, and quality of life of patients, and its mechanism involves multiple pathways such as regulating inflammatory factors, neuroendocrine function, and energy metabolism. In terms of safety, acupuncture only causes mild and transient adverse reactions, with no reports of serious events, and has a good risk-benefit ratio. This review aims to provide evidence-based support for the use of acupuncture in treating CRF and promote its standardized application and individualized development in the field of integrated traditional Chinese and Western medicine for tumor rehabilitation.
文章引用：马丹, 孙晓伟. 针灸治疗化疗所致癌因性疲乏的疗效与安全性：一项系统综述[J]. 临床医学进展, 2025, 15(10): 939-944. https://doi.org/10.12677/acm.2025.15102840

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