甲状旁腺功能亢进颌骨改变误诊1例报告

The Report of Hyperparathyroidism Jaw Changes Is Misdiagnosed

摘要: 原发性甲状旁腺功能亢进(primary hyperparathyroidism, PHPT)是由于甲状旁腺合成、分泌过多甲状旁腺激素引起钙、磷和骨代谢紊乱的一种全身性疾病，表现为高血钙、低血磷、肾结石和骨骼病变等，因其发展缓慢，发病隐匿，临床表现多样，缺乏特异性，且合并颌骨病变并不多见，故其在临床上极易误诊，现报道1例误诊为“下颌骨恶性肿物”的原发性甲状旁腺功能亢进病例。 Primary hyperparathyroidism is a systemic disease due to the disorders of calcium, phosphorus, and metabolic bone caused by the synthesis and hyper secretion of parathyroid hormone, which is characterized by hypercalcemia, hypophosphatemia, kidney stones, bone lesions, etc. The progression of PHPT is slow and it is not easy to find. At the same time, the clinical manifestations of PHPT are diverse and lack specificity. More importantly, the lesions of the jaw bone are rare, so it is easily misdiagnosed in the clinical practice. A case that the primary hyperparathyroidism is misdiagnosed as malignant neoplasm of mandible is reported in this paper.