新型钛基光催化剂对水体中耐药菌的消除性能研究

Study on the Elimination Performance of Novel Titanium-Based Photocatalyst for Drug-Resistant Bacteria in Water

摘要: 研究通过利用新型钛基光催化剂作为水体净化材料，评估了其对水环境中典型耐药菌的灭活效果。结果表明，该新型钛基光催化剂在可见光下具备优异的光催化灭菌能力，且灭菌效率与光催化剂的负载呈现先上升后下降的趋势。通过探究不同因素对光催化灭活耐药菌效率的影响发现：耐药菌灭活效率随光照强度的增强而升高；pH在6~8范围内灭活率较高；在正常环境水平下，不同无机离子的存在对光催化灭活耐药菌的性能无显著影响。此外，通过扫描电镜与活性氧检测分析证实，在模拟太阳光照射下，该新型钛基光催化剂产生的活性氧自由基可造成菌体结构损伤、细胞膜通透性改变并引起细胞内氧化应激反应，最终导致耐药菌死亡。这说明研究使用的新型钛基光催化剂具有良好的耐药菌消除性能，为控制水环境中耐药菌污染问题提供了新的思路。

Abstract: This study evaluated the inactivation efficacy of a novel titanium-based photocatalyst against typical drug-resistant bacteria in the aquatic environment, utilizing it as a water purification material. The results demonstrated that this novel titanium-based photocatalyst possessed excellent photocatalytic sterilization capability, and its sterilization efficiency exhibited a trend of initially increasing and subsequently decreasing as the photocatalyst loading varied. An investigation into the effects of various factors on the efficiency of photocatalytic inactivation of drug-resistant bacteria revealed that the inactivation efficiency against drug-resistant bacteria increased with increasing light intensity. The inactivation rates were higher within the pH range of 6 to 8. And under normal environmental conditions, the presence of various inorganic ions had no significant impact on the performance of photocatalytic inactivation of drug-resistant bacteria. Furthermore, analyses utilizing scanning electron microscopy and reactive oxygen species detection confirmed that, under simulated solar light irradiation, the reactive oxygen species generated by this novel titanium-based photocatalyst could induce structural damage to bacterial cells, alter cell membrane permeability, and trigger intracellular oxidative stress responses, ultimately leading to the death of the drug-resistant bacteria. The novel titanium-based photocatalyst employed in this study demonstrates superior efficacy in eliminating drug-resistant bacteria, thereby offering a novel perspective for addressing the issue of drug-resistant bacterial contamination in aquatic environments.