基于Marching Cubes与Ray Casting的BNCT剂量三维可视化方法研究

Research on 3D Visualization Method of BNCT Dose Based on Marching Cubes and Ray Casting

摘要: BNCT剂量场受中子输运、硼浓度和组织成分共同影响，空间分布复杂。二维切片能显示局部剂量，但难以解释热点与脑部解剖结构的对应关系。本文提出一种面向BNCT脑部剂量分析的CT-RTDOSE融合三维可视化方法。程序读取CT序列和RTDOSE数据，将剂量体重采样到CT网格；基于HU阈值和形态学规则构建头部、颅骨和脑区近似掩膜；利用Marching Cubes重建多层解剖表面，并用Ray Casting绘制连续剂量场。两类结果在统一坐标系下融合显示，并与三正交切片联动。单病例结果表明，该方法能够同时保留剂量连续性和解剖参照。当前病例中，重采样前后最大剂量和峰值位置一致，说明该流程在已对齐数据上保持了空间一致性。与单纯二维切片或单独三维剂量体相比，该方法更便于热点定位、边界判断和空间理解。

Abstract: BNCT dose fields are shaped by neutron transport, boron concentration, and tissue composition, and therefore exhibit strong spatial heterogeneity. Two-dimensional slices can show local dose values, but they are weak at explaining the spatial relationship between dose hotspots and brain anatomy. This study proposes a CT-RTDOSE fused three-dimensional visualization method for BNCT brain dose analysis. The program loads CT series and RTDOSE data, resamples dose to the CT grid, builds approximate masks of the head, skull, and brain region with HU thresholds and morphological rules, reconstructs layered anatomical surfaces with Marching Cubes, and renders the continuous dose field with Ray Casting. The two results are fused in a unified coordinate system and linked with three orthogonal slices. A single-case study shows that the method preserves dose continuity while providing clear anatomical reference. In the current case, the maximum dose and peak location remain unchanged before and after resampling, indicating good spatial consistency for aligned data. Compared with slice-only display or dose-volume-only display, the proposed method is more effective for hotspot localization, boundary inspection, and spatial interpretation.