以专科护士为主导的营养干预对晚期胃肠道肿瘤化疗患者营养改善研究

Dominated by Professional Nurse Nutritional Intervention in Patients with Terminal Gastrointestinal Tumor Chemotherapy: An Integrative Research

摘要: 目的：分析以专科护士为主导的营养治疗团队对晚期胃肠道肿瘤化疗患者营养改善指标的影响。方法：2014年1月1日至2015年6月30日住院化疗结直肠癌患者，共248人，使用NRS2002评分 ≥ 3分的结肠癌肿瘤患者共60人，使用单盲随机分组，分为干预组及对照组，干预组30人，对照组30人，干预组采用由营养专科护士、管床医生、家属、患者组成的团队，制定患者个性化营养食谱；对照组采用常规饮食指导；采用SPSS20.0，采用自身配对t检验统计方法，评价两组不同时点的营养指标改善情况以及自身治疗前后营养改善差值对比，p < 0.05，有统计学意义。结果：对照组及干预组各30人，数据显示两组间改善值血清前白蛋白、血清白蛋白均有统计学意义(p < 0.05)；另外干预组干预前后血清前白蛋白差值在干预后1个月至5个月均有统计学差异(p < 0.05)，血清白蛋白差值在干预后2个月至5个月也有统计学差异(p < 0.05)。结论：以专科护士为主导的营养治疗团队对晚期结直肠肿瘤化疗患者的营养指标有明显改善效果，值得大家推广应用。

Abstract: Objective: To evaluate the effect of nutritional improvement in colorectal cancer patients with chemotherapy after nutritional therapy leading by specialized nurse teams. Methods: 248 colo-rectal cancer patients (NRS 2002 score is more than or equal to 3 points) with chemotherapy of The Third Affiliated Hospital of Sun Yat-sen University form January 1st 2014 to June 30th 2015 were collected. The patients were randomly divided into intervention group (30 patients) and the control group (30 patients). The intervention group received personalized recipe which was developed by a team containing professional nurses, chief psychiatrist, family members and patients themselves. The control group was treated with a normal diet guidance. The change about nutrition index of different time and their nutrition improved difference contrast before and after the treatment, and statistical analysis was made when p was less than 0.05. Results: The two groups with 30 patients in each group. The serum albumin and the preprotein improved after 5 months of chemotherapy than before chemotherapy in intervention group (p < 0.05). The D-value of the serum albumin and the preprotein before chemotherapy and 5 months after chemotherapy were improved more significantly in intervention group than the control group (p < 0.05). Conclusion: There is a significant nutritional improvement in colorectal cancer patients with chemotherapy after nutritional therapy leading by specialized nurse teams, which is worthy of application.