NET-1基因与肝细胞癌的研究进展
Research Progress of NET-1 Gene and Hepatocellular Carcinoma
DOI: 10.12677/ACM.2020.1011371, PDF,    科研立项经费支持
作者: 杨 斌, 刘 欢, 孙象军*：山东第一医科大学(山东省医学科学院)，临沂市人民医院，山东 临沂；张东宁：青岛大学第十一临床医学院临沂市人民医院，山东 临沂
关键词: 肝细胞癌；NET-1；MIB-1；PCNA；Ki-67；Hepatocellular Carcinoma； NET-1； MIB-1； PCNA； Ki-67
摘要: NET-1基因是新发现的肿瘤相关基因，与肝细胞癌的发生发展密切相关，研究发现NET-1通过PI3K/AKT等各种信号通路和相关分子共同促进HCC的发生发展，可作为肝细胞癌早期诊断的生物标志物和治疗靶点。本文综述近几年NET1基因在肝癌中的研究进展，揭示其潜在分子机制，具有重要临床意义。
Abstract: NET-1 gene is a newly discovered tumor-related gene, which is closely related to the occurrence and development of hepatocellular carcinoma. Research has found that NET-1 promotes the occurrence and development of HCC through various signaling pathways such as PI3K/AKT and related molecules. It can be used as an early stage of hepatocellular carcinoma, diagnostic biomarkers and therapeutic targets. This article reviews the research progress of NET-1 gene in liver cancer in recent years, reveals its potential molecular mechanism, and has important clinical significance.
文章引用：杨斌, 张东宁, 刘欢, 孙象军. NET-1基因与肝细胞癌的研究进展[J]. 临床医学进展, 2020, 10(11): 2457-2462. https://doi.org/10.12677/ACM.2020.1011371

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