156例外阴癌临床特征与预后分析

Clinical Features and Prognostic Factors of 156 Cases of Vulvar Cancer

摘要: 目的：分析影响外阴癌预后的因素。方法：回顾性分析2008年6月至2016年6月于青岛大学附属医院就诊的156例外阴癌患者临床资料。结果：影响外阴癌预后的独立危险因素包括合并自身免疫性疾病、肿瘤浸润深度、腹股沟淋巴结转移。合并有自身免疫性疾病、浸润深度 > 1 mm、腹股沟淋巴结转移阳性患者的5年生存率分别为49.4%、45.1%、37.0% (P < 0.05)。结论：积极治疗自身免疫性疾病可帮助改善外阴癌预后，术前评估应明确肿瘤浸润深度与腹股沟淋巴结转移情况，来确定足够的手术范围或术后是否进行辅助放化疗。

Abstract: Objective: To explore the risks of vulvar carcinoma. Method: From June 2008 to June 2016, 156 patients with vulvar carcinoma from the Affiliated Hospital of Qingdao University were analyzed retrospectively. Result: The independent prognostic factors are: autoimmune disease, infiltration depth and lymph node metastasis. The 5 years survival rate of someone who had autoimmune disease, infiltration depth more than 1 mm, lymph node metastasis were 49.4%, 45.1%, 37.0% (P < 0.05). Conclusion: Positive treatment of autoimmune diseases can improve the prognosis. Before the operation, we should certain the infliltration depth and lymph node metastasis to choose appropriate surgery, radiotherapy and chemotherapy.