低浓度阿托品滴眼液在青少年近视防控中的疗效分析

Efficacy Analysis of Low Concentration Atropine Eye Drops in Prevention and Control of Myopia in Adolescents

摘要: 目的：研究分析0.01%低浓度阿托品滴眼液在青少年近视防控中的疗效及安全性。方法：选取2020年4月~2021年4月在门诊就诊的青少年中低度近视(<−6.0D)近视者120例，用数字随机法进行分两组各60例；对照组给予维生素B12滴眼液常规方法治疗；研究组给予0.01%阿托品滴眼液治疗，对比两组的临床治疗效果和安全性。结果：研究组治疗效果显著优于对照组，差异有统计意义(P < 0.01)；控制眼轴的增幅也小于对照组，差异有统计意义(P < 0.01)；两组不良反应发生率相比较差异较小，无统计意义(P > 0.05)。结论：0.01%阿托品滴眼液在青少年近视防控中的效果及安全性均较好，值得临床推广使用。

Abstract: Objective: To study and analyze the efficacy and safety of 0.01% low concentration atropine eye drops in prevention and control of juvenile myopia. Methods: A total of 120 adolescent patients with moderate and low myopia (<−6.00D) from April 2020 to April 2021 were selected and randomly divided into two groups with 60 cases in each group. The control group was treated with vitamin B12 eye drops and the study group was treated with 0.01% atropine eye drops. The clinical efficacy and safety of the two groups were compared. Results: The treatment effect of the study group was significantly better than that of the control group; the difference was statistically significant (P < 0.01). The increase of the control eye axis was also less than that of the control group, the difference was statistically significant (P < 0.01); the difference in the incidence of adverse reactions between the two groups was small, there was no statistical significance (P > 0.05). Conclusion: 0.01% atropine eye drops has good effect and safety in prevention and control of juvenile myopia, which is worthy of clinical application.