肝脏神经内分泌肿瘤的临床特点及治疗

Clinical Characteristics and Treatment of Hepatic Neurorndorine Neoplasms

摘要: 神经内分泌肿瘤(neurorndorine neoplasms, NENs)指的是那些来源于神经内分泌系统的肿瘤。NENs在临床上比较少见，故原发的肝脏神经内分泌肿瘤更少见。NENs易发生肝转移，临床上见到的肝脏神经内分泌肿瘤往往为转移性的肝脏神经内分泌肿瘤，其临床症状和影像学检查结果都没有明显的特异性，因此必须结合多方面的检查手段，排除肝外原发可能。基于目前这种情况，原发或继发肝脏的NENs的鉴别及诊断是一个复杂的过程，单纯的病理结果并不能完全明确原发疾病。结合目前的情况，有必要对肝脏NENs的临床特征、诊断以及治疗进行系统的梳理。

Abstract: Neurorndorine neoplasms (NENs) are a kind of tumor derived from neuroendocrine system. NENs are relatively rare in clinic, so primary neuroendocrine neoplasms of the liver are rarer. NENs are prone to liver metastasis. The hepatic neuroendocrine neoplasms seen clinically are often metastatic hepatic neuroendocrine neoplasms, and their clinical symptoms and imaging findings have no obvious specificity, so it is necessary to combine various examination methods to exclude the existence of extrahepatic primary lesions in order to diagnose. Based on the current situation, the differentiation and diagnosis of primary or secondary liver NENs are a complex process, simple pathological results cannot completely identify the primary disease. Therefore, this article reviews the clinical features, diagnosis, differential diagnosis and treatment of hepatic neuroendocrine neoplasms.