康妇消炎栓用于治疗药流不全的临床疗效观察

Clinical Observation of Kangfu Xiaoyan Suppository in Treating Incomplete Drug Abortion

摘要: 目的：探讨康妇消炎栓用于治疗药流不全的临床疗效，为临床治疗提供参考依据。方法：采用随机平行对照法，将符合纳入标准的药流不全保守治疗患者80例，随机将患者分为两组；对照组40例：应用复方益母草膏治疗；实验组40例：直肠外用康妇消炎栓，同时口服复方益母草膏进行治疗；两组均连续治疗14天，在治疗7天后及治疗结束时，分别对患者的临床症状、阴道出血持续时间、宫腔残留物大小、血清β-绒毛膜促性腺激素(β-HCG)水平等指标进行动态观察，并随访至月经复潮，判定疗效。结果：治疗前，两组患者的年龄、孕次、停经天数、血清β-HCG水平、宫内妊娠残留物直径大小等基础数据相比较，均无差异性(P > 0.05)。治疗7天、14天后，两组患者的血清β-HCG水平均呈下降趋势，但实验组下降幅度大于对照组(P < 0.05)。实验组阴道流血时间明显短于对照组(P < 0.05)。实验组宫内残留物消失或缩小明显优于对照组(P < 0.05)。在促进月经周期恢复方面，实验组的月经复潮时间明显短于对照组(P < 0.05)。结论：药流不全患者应用康妇消炎栓进行治疗，能有效促进宫内残留物排出，明显降低血清β-HCG水平，改善阴道流血情况和加速正常月经周期的恢复，治疗药流不全成功率高。

Abstract: Objective: To explore the clinical effect of Kangfu Xiaoyan suppository in treating incomplete drug abortion, and to provide reference for clinical treatment. Methods: In this study, random parallel control method was used, 80 patients who met the inclusion criteria were randomly divided into two groups: Control Group (40 cases) were treated with compound Herba Leonuri Ointment; Experimental Group (40 cases) with external use of Kangfu Xiaoyan suppository, both groups were treated continuously for 14 days, after 7 days of treatment and at the end of treatment, the clinical symptoms, the duration of vaginal bleeding, the size of uterine cavity residue and the level of serum β-HCG were observed dynamically, and follow-up to Menarche, determine the efficacy. Results: Before treatment, there was no difference between the two groups in age, duration of pregnancy, days of menopause, serum β-HCG level and intrauterine pregnancy residue diameter (P > 0.05). Seven days, 14 days after treatment, the serum β-HCG level in the two groups was lower than that before treatment, but the experimental group was better than the control group (P < 0.05). The duration of vaginal bleeding in the experimental group was shorter than that in the control group (P < 0.05). The disappearance or contraction of intrauterine remnants in the experimental group was better than that in the control group (P < 0.05). The time of menarche in the experimental group was better than that in the control group (P < 0.05). Conclusion: Kangfu Xiaoyan suppository can effectively promote the excretion of intrauterine residues, significantly reduce serum β-HCG levels, improve vaginal bleeding and speed up the recovery of normal menstrual cycle, the success rate of treating incomplete drug abortion is high.