系统性红斑狼疮肺受累研究进展
Research Progress of Lung Involvement in Systemic Lupus Erythematosus
DOI: 10.12677/ACM.2023.134896, PDF,   
作者: 杨真真：济宁医学院临床医学院，山东 济宁；李 健：济宁医学院附属医院，山东 济宁
关键词: 系统性红斑狼疮；胸膜肺；肺；Systemic Lupus Erythematosus； Pleuropulmonary； Lung
摘要: 系统性红斑狼疮(Systemic Lupus Erythematosus)是一种累及多器官的自身免疫性疾病，包括肺受累。SLE肺受累的确切机制尚不清楚。SLE可以引起多种肺部疾病，包括狼疮性胸膜炎、胸腔积液、急性狼疮性肺炎、肺萎缩综合征、间质性肺病、弥漫性肺泡出血(DAH)、肺动脉高压和肺栓塞。SLE肺受累有许多诊断工具，包括胸部X线(CXR)、计算机断层扫描(CT)、肺功能检查(PFT)、支气管肺泡灌洗、活检、磁共振(MRI)、FDG-PET。治疗上一般采用皮质类固醇、环磷酰胺等免疫抑制疗法。本文就SLE肺受累的发病机制、诊断和治疗等方面的文献作一综述。
Abstract: Systemic lupus erythematosus is an autoimmune disease that involves multiple organs, including pulmonary involvement. The precise mechanism of lung involvement in SLE is unknown. SLE can cause various pulmonary diseases, including lupus pleuritis, pleural effusion, acute lupus pneu-monitis, shrinking lung syndrome, interstitial lung disease, diffuse alveolar hemorrhage (DAH), pulmonary arterial hypertension, and pulmonary embolism. Pleuropulmonary involvement in SLE requires many diagnostic tools, including chest X-ray (CXR), computed tomography (CT), pulmonary function tests (PFT), bronchoalveolar lavage, biopsy, MRI, FDG-PET. Immunosuppression therapies such as corticosteroids and cyclophosphamide are generally used in the treatment. This article re-views the literature on the pathogenesis, diagnosis and treatment of SLE lung involvement.
文章引用：杨真真, 李健. 系统性红斑狼疮肺受累研究进展[J]. 临床医学进展, 2023, 13(4): 6374-6383. https://doi.org/10.12677/ACM.2023.134896

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