急性结石性胆囊炎伴CA199异常升高1例
Acute Calculous Cholecystitis with Abnormally Elevated CA199: A Case Report
DOI: 10.12677/ACRS.2022.111001, PDF,   
作者: 刘立民, 万柏江, 刘 卓, 赵 月：国家电网公司北京电力医院，北京
关键词: 急性胆囊炎；CA199；Acute Cholecystitis； CA199
摘要: 急性结石性胆囊炎是胆囊管梗阻及细菌感染导致的炎症，普外科常见急腹症之一。糖类抗原199 (carbohydrate antigen 199, CA199)是在消化系统恶性肿瘤中发现的一种肿瘤相关抗原，也是目前对胰腺癌敏感性最高的肿瘤标记物。某些良性疾病也会引起不同程度的CA199值升高，但合并CA199异常升高非常罕见，容易导致误诊，现报道1例我院收治的急性结石性胆囊炎合并CA199异常升高病例资料。
Abstract: Acute calculous cholecystitis is an inflammation caused by cystic duct obstruction and bacterial infection, which is one of the common acute abdominal diseases in general surgery. Glycochain anti-gen 199 (CA199) is a tumor-associated antigen found in digestive malignancies and is currently the most sensitive tumor marker for pancreatic cancer. Some benign diseases may also cause increased CA199 value to varying degrees, but the combination of abnormal increase of CA199 is very rare, which is easy to lead to misdiagnosis. Now we report the data of one case of acute calculous chole-cystitis combined with abnormal increase of CA199 treated in our hospital.
文章引用：刘立民, 万柏江, 刘卓, 赵月. 急性结石性胆囊炎伴CA199异常升高1例[J]. 亚洲外科手术病例研究, 2022, 11(1): 1-4. https://doi.org/10.12677/ACRS.2022.111001

参考文献

[1] 顾越雷, 杨孙虎, 樊强, 张龙龙, 陈宏伟. 老年人急性结石性胆囊炎行急诊与延期腹腔镜胆囊切除术的疗效分析[J]. 腹腔镜外科杂志, 2018, 23(3): 217-220.
[2] 张永东. 血清CA199、CA242、CA125联合检测对胆囊癌患者诊断的临床价值研究[J]. 肝胆外科杂志, 2016, 24(2): 106-110.
[3] 许卫娜, 王婷. 患者血清CEA、CA724、CA199水平对胰腺癌的评估价值[J]. 实用癌症杂志, 2019, 34(5): 747-749.
[4] 万祖安. 血清CEA及CA199水平在胃肠道肿瘤诊断中的应用价值探讨[J]. 世界最新医学信息文摘, 2019, 19(80): 218.
[5] 王梅, 孟华, 刘晓颖. AFP、CEA、CA199、CA724联合检测在消化道恶性肿瘤中的临床价值[J]. 胃肠病学和肝病学杂志, 2011, 20(6): 546-548.
[6] 丁平安, 王冬, 等. 急性无结石性坏疽穿孔性胆囊炎合并CA199异常增高一例[J]. 腹部外科, 2021, 34(6): 492.
[7] Fukasawa, H., Kaneko, M., Niwa, H., Yasuda, H., Kumagai, H. and Furuya, R. (2018) Carbohydrate Antigen 19-9 Is Significantly Elevated in Autosomal Dominant Polycystic Kidney Disease. Nephrology (Carlton), 23, 210-216. [Google Scholar] [CrossRef] [PubMed]
[8] 张勇, 张学明, 张伟辉. CA199在良恶性梗阻性黄疸鉴别应用中的研究进展[J]. 医学综述, 2017, 23(6): 1080-1084.
[9] Marrelli, D., Caruso, S., Pedrazzani, C., et al. (2009) CA19-9 Se-rum Levels in Obstructive Jaundice: Clinical Value in Benign and Malignant Condition. The American Journal of Sur-gery, 198, 333-339. [Google Scholar] [CrossRef] [PubMed]
[10] 杨东, 等. CA199在胆囊结石患者中表达[J]. 浙江临床医学, 2014, 26(12): 1923-1924.
[11] Meller, J., Sahimann, C.O., Guroeak, O., et al. (2009) FDG-PET in Patients with Fever of Unknown Origin: The Importance of Diagnosing Large Vessel Vasculitis. The Quarterly Journal of Nuclear Medicine and Molecular Imaging, 53, 5l-63.
[12] 刘一, 李亚明, 等. 18F-FDG PET/CT在胰腺良恶性病变的诊断及鉴别诊断中的价值[J]. 中国医科大学学报, 2014, 43(6): 547-558.

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