标题:
基于RiceWiki的水稻抗逆基因审编与分析The Curation and Analysis of Rice Stress-Resistance Genes Based on RiceWiki
作者:
张烨, 陈玲玲, 章张
关键字:
RiceWiki, 审编, 抗逆性RiceWiki, Curation, Stress-Resistance
期刊名称:
《Hans Journal of Computational Biology》, Vol.5 No.3, 2015-09-08
摘要:
在中国，审编是一个新领域，对各种生物学信息进行审编是今后的发展趋势。本文收集了文献中耐盐、耐旱、耐热、耐寒、抗植株矮小、抗倒伏、抗白叶枯病、抗稻瘟病这8种水稻抗逆基因，共计500个。以RiceWiki为平台，对搜集的水稻抗逆基因进行审编，发布到RiceWiki上，并对搜集的500个基因进行了分析。首先分析了抗逆基因之间的蛋白互作，得到了61个蛋白质间的78个蛋白互作。共表达分析表明有明显共表达趋势的蛋白对占21.61%，进一步表明了这些抗逆基因编码的蛋白可以互作。最后，利用argiGO对GO富集度进行了分析，结果表明和压力相关的GO语义的显著性水平较高。
Curation is a frontier in China, the biocuration of all kinds of biological information is the devel-opment tendency. In this paper, 500 rice genes of eight kinds stress-resistance were collected from literature: salinity tolerance, drought tolerance, cold tolerance, heat tolerance, dwarf resis-tance, lodging resistance, bacterial blight resistance and blast resistance. Curating the rice stress- resistance genes based on the platform of RiceWiki and publishing on RiceWiki. The 500 rice stress-resistance genes were further analyzed. First, the protein-protein interactions between stress-resistance rice genes were analyzed which containing 78 protein interactions among 61 proteins. The results of co-expression analysis indicated that 21.61% protein pairs have a tendency to co-expression, which showed the protein encoded by the stress-resistance genes could interact with each other. Finally, the GO enrichment is analyzed by argiGO, the results indicated that the significant level of GO terms related to stress is higher.