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C. E. Fabre, P. J. Blanc and G. Goma. Production of 2-phenyl- ethyl alcohol by Kluyveromyces marxianus. Biotechnology Progress, 1998, 14(2): 270-274.

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  • 标题: 生物催化法生产2-苯乙醇的研究现状The Study of Biotechnological Production of 2-Phenylethanol

    作者: 曹明乐, 姜兴林, 张海波, 咸漠, 黄峰

    关键字: 2-苯乙醇, 香料, 生物催化, 艾利氏途径, 原位萃取2-Phenylethanol; Spices; Bio-Catalytic; Ehrlich Pathway; ISPR

    期刊名称: 《Bioprocess》, Vol.2 No.2, 2012-06-26

    摘要: 2-苯乙醇(2-Phenylethanol)也叫β-苯乙醇,英文简称2-PE,具有淡雅、细腻、持久、玫瑰香味的芳香族香气物质。2-苯乙醇可以作为香料广泛应用于香水、化妆品、食品等行业,此外2-苯乙醇在医药中间体及精细化工等行业也有重要的开发价值。目前2-苯乙醇主要是通过化学方法合成,生物催化法具有能耗低、环境污染小及人们对“天然”产品的要求也越来越高使得生物催化法来合成“天然”的2-苯乙醇受到越来越多的重视。本综述主要介绍了2-苯乙醇的合成现状,并且着重对生物合成方法、代谢途径及当前发酵方法优缺点进行了论述。 2-Phenylethanol (β-Phenylethanol) is aromatic flavour and fragrance compound with an elegant, fine, endure, rose-like odour. It can be used as additives in perfume, cosmetic, food industries. It also can be used as pharmaceutical intermediates and fine chemicals. So far, 2-PE is mainly produced chemically. The biosynthesis of 2-PE is receiving more attentions, because of its low energy consumption, environmentally friendly, and the demand for the “natural” 2-PE. This review introduces the production of 2-PE especially the biosynthesis method, metabolic pathway, and fermentation method.

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