标题:
心脑佳配方对慢性酒精中毒大鼠学习记忆及前额叶皮质丝切蛋白含量的影响Effect of Xin Nao Jia Formula on the Learning and Memory Abilities and Cofilin Content of Prefrontal Cortex in the Chronic Alcoholism Rats
作者:
宦楠楠, 姜洪波, 侯丽君, 安娜, 徐磊, 杜爱林, 万光瑞
关键字:
心脑佳配方, 学习记忆, 丝切蛋白Xin Nao Jia Formula; Learning and Memory; Cofilin
期刊名称:
《International Journal of Psychiatry and Neurology》, Vol.2 No.3, 2014-05-19
摘要:
目的：研究心脑佳配方对慢性酒精中毒大鼠学习记忆及前额叶皮质丝切蛋白含量的影响。方法：建立大鼠慢性酒精中毒模型、Y-迷宫实验探究心脑佳配方对学习记忆的影响、免疫组化检测皮质额叶丝切蛋白含量。结果：学习记忆测试显示对照组大鼠学习记忆成绩比酒精中毒模型组明显升高(P
Objective: To study the effect of xin nao jia formula on the learning and memory abilities and cofilin content of prefrontal cortex in the chronic alcoholism rats. Methods: Establish chronic alcoholism rat model; use Y-maze experiment to explore the learning and memory abilities of xin nao jia formula and immunohistochemical experiment to detect the cofilin content in prefrontal cortex. Results: Learning and memory tests showed that the learning and memory scores of control group rats have significantly increased more than the alcohol poisoned model group (P