标题:
异腈参与的多组分反应新进展New Progresses of Multicomponent
Reactions Based on Isocyanides
作者:
靳文静, 韩光, 何心伟, 胡凯, 商永嘉
关键字:
异腈, 多组分反应, 组合化学, 杂环化合物Isocyanides, Multicomponent Reactions, Combinational Chemistry, Heterocyclic Compounds
期刊名称:
《Studies in Synthetic Chemistry》, Vol.2 No.1, 2014-05-28
摘要:
本文综述了异腈参与的多组分反应合成一些杂环化合物的最新研究进展，主要介绍了异腈参与的Ugi多组分反应的几种新型反应，详细地介绍了各种反应对底物的要求、反应条件、反应的选择性、产率以及机理的研究。同时对近年来发展的异腈参与的几种新型Passerini多组分反应进行了简单介绍。对异腈参与的多组分反应合成杂环化合物的前景进行了展望。
This paper reviewed the new progresses of the multicomponent reactions based on isocyanides to synthesize the heterocyclic compounds, and mainly introduced some new reactions of the Ugi multicomponent reactions. The request of substrates, reaction conditions, selectivity, yield and mechanism were investigated in detail. Meanwhile, a brief introduction of some new Passerini multicomponent reactions was given. New breakthroughs in this field were intensely expected.