标题:
西南菝葜的化学成分研究Studies on the Chemical Constituents of Rhizomes of Smilax bockii Warb.
作者:
邹琼宇, 唐玉莲, 陈迪钊, 吴海峰
关键字:
金刚藤, 脑苷, 黄酮, 分离鉴定Smilax, Cerebroside, Flavonoids, Isolation and Identification
期刊名称:
《Journal of Organic Chemistry Research》, Vol.3 No.1, 2015-02-26
摘要:
目的：研究西南菝葜的化学成分。方法：利用多种色谱层析方法分离化学成分，通过ESI-MS/MS及NMR等波谱方法鉴定结构。结果：共分离鉴定出12种化合物，依次是薯蓣皂苷元(1)、邻苯二甲酸-双-2乙基已酯(2)、香菜内酯(3)、山萘酚(5)、双氢山萘酚(6)、槲皮素(7)、双氢槲皮素(8)、大豆脑苷II(9)、芝麻脑苷(10)、异黄杞苷(11)、5-O-β-D-葡萄糖-山萘酚(12)、5-O-β-D-葡萄糖-双氢山萘酚(13)。结论：化合物2、3、9、10为首次从金刚藤中分离得到的化合物。Objective: To study the chemical constituents of rhizomes of Smilax bockii Warb. Methods: The constituents were isolated and purified by colunm chromatography and preparative TLC. Their structures were identified on the basis of comprehensive spectroscopic methods including ESI-MS and spectral data (1H, 13C-NMR). Results: Twelve compounds were isolated and identified as dios-genin (1), phthalic acid derivative (2), coriander lactone (3), resveratrol (4), kaempferol (5), di-hydro kaempferol (6), quercetin (7), dihydroquercetin (8), soya cerebroside II (9), sesame cere-broside (10), isoengelitin (11), kaempferol 5-O-β-D-glucopyranoside (12), and dihydrokaempferol 5- O-β-D-glucopyranoside (13). Conclusion: Compounds 2, 3, 9, 10 were isolated from the genus Smilax for the first time.