基本情况
郭晓东,武汉协和医院(也称华中科技大学同济医学院附属协和医院)骨科教授、主任医师、博士生导师。华中科技大学同济医学院附属协和医院骨科医学博士、加拿大多伦多大学博士后。教育部新世纪优秀人才、湖北省青年科技奖获得者、骨质疏松与骨矿盐疾病临床研究杰出青年学者。中华医学会骨质疏松与骨矿盐疾病中青年学术委员会副主任委员、湖北省老年学学会骨质疏松专业委员会副主任委员。
研究领域
创伤骨科、脊柱脊髓损伤、骨软骨组织工程学与纳米仿生骨修复材料
论文发表
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Zhenyu Lin; Zhixia Duan; Xiaodong Guo* (通讯作者); Qixin Zheng; Daping Quan; Shuhua Yang. Experimental research
of biomimetic PLGA-(PEG-ASP)n copolymer loaded with a novel synthetic
BMP-2 related peptide in vitro and in vivo. Journal of Controlled Release,
2010;144:190–195.http://dx.doi.org/10.1016/j.jconrel.2010.02.016 (SCI收录, IF(2010)= 7.164)
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Xiaodong Guo, Tasneem Zahir, Molly S. Shoichet, Cindi Morshead, Yusuke Katayama,
and Charles H. Tator. The effect of growth factors and soluble Nogo66 receptor
protein on transplanted neural stem/progenitor survival and axonalregeneration
after complete transection of rat spinal cord. Cell Transplantation, 2012,
(accepted, SCI收录, IF(2010)=6.204)
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Shuyun Xu, Bin Wu, Xiaodong
Guo (通讯作者). BMP2 related oligopeptide
as a potential therapeutic agent to accelerate bone formation and bone
defect repairing in osteoporotic fracture: effect on rat cranial bone defects
repairing. Bone, 2010; 47(Suppl 3): S368 (Abstract) (IF(2010)= 4.601)
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Shuyun Xu, Bin Wu, Xiaodong Guo (通讯作者). BMP2 related oligopeptide
as a potential therapeutic agent to accelerate bone formation and one
defect repairing in osteoporotic fracture: effect on osteogenic differentiation
and mineralization of BMSCs. Bone, 2010; 47(Suppl 3): S375 (Abstract)(IF(2010)=
4.601)
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Jingfeng Li, Jijun Hong, Qixin Zheng*, Xiaodong Guo*, Shenghui Lan, Fuzhai Cui,
Haitao Pan, Zhenwei Zou, Chao Chen. Repair of rat cranial bone defects with
nHAC/PLLA and BMP-2-related peptide or rhBMP-2. J Orthop Res. 2011 Apr 15.doi:
10.1002/jor.21439. [Epub ahead of print] (SCI收录,IF(2009)=
3.112)
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Wu B, Zheng QX, Guo XD(通讯作者), Wu YC, Wang Y, Cui
FZ.Preparation and ectopic osteogenesis in vivo of scaffold based on
mineralized recombinant human-like collagen loaded with synthetic
BMP-2-derived peptide. Biomed.Mater. 2008; 3(4): 044111. doi:
10.1088/1748-6041/3/4/044111 (SCI及EI收录, IF(2010)=2.467)
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Guo XD(通讯作者), Zheng J, Kulbatski I, et al. Bone regeneration
with active angiogenesis by bFGF gene transduced mesenchymal stem cells
seeded on porous β-TCP ceramics scaffolds. Biomed.
Mater. 2006;1:93-99.
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http://stacks.iop.org/1748-605X/1/93(SCI收录,IF(2010)=2.467)
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Guo XD(通讯作者), Zheng Qixin, Yang Shuhua, et al.Repair of
full-thickness articular cartilage defects by cultured mesenchymal stem
cells transfected with the transforming growth factor β1
gene. Biomedical Materials, 2006; 1: 206-215.
http://stacks.iop.org/1748-605X/1/206. (SCI收录,IF(2010)=2.467)
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Jingfeng Li, Zhenyu Lin, Qixin Zheng* , Xiaodong Guo*(共同通讯作者), Shenghui Lan, Sunan Liu, Shuhua Yang. Repair of rabbit radial bone
defects using true bone ceramics combined with BMP-2 related peptide and type
I collagen. Materials science and engineering:C, 2010,30(8):1273-1280.(SCI及EI收录, IF(2010)= 2.178)
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Pan HT, Zheng QX, Guo XD(通讯作者). A novel synthetic peptide
vector system for optimal gene delivery to bone marrow stromal cells. J Peptide
Science, 2007, 13(3): 154-163. (SCI收录, IF(2010)=1.954)