基本情况

雷博，重庆医科大学附属第一医院眼科教授、研究员。五份中华眼科系列杂志编委，美国ARVO年会和国际临床视觉电生理学会（ISCEV）视觉电生理授课专家。中华医学会眼科分会电生理学组副组长，中国医师协会眼科医师分会视觉电生理学组副主任委员、中国眼科发展策略分委会委员。主持国家自然科学基金5项，发表SCI论文近60篇被引用1300余次。国家自然科学基金及多个省市自然科学基金评审专家。2011年获中华眼科学会奖。

 

研究领域

视网膜功能和视网膜疾病诊断及治疗

 

教育背景

2001年 博士后，美国密歇根大学医学院

1997年 博士，以色列技术学院医学院

1989年 硕士，河南医科大学

1986年 学士，河南医科大学医学系

 

工作经历

2009年至今   副主任，重庆医科大学附属第一医院、重庆市眼科学重点实验室

2001年至2009年 科学助理教授，美国密苏里大学眼科及视觉

1986年至1993年 眼科主治医师，河南医科大学第一附属医院眼科

 

论文发表

  1. Yiguo Qiu, Lifei Tao, Chunyan Lei, Jiaming Wang, Peizeng Yang, Qiuhong Li, Bo Lei. Downregulating p22phox ameliorates inflammatory response in Angiotensin II-induced oxidative stress by regulating MAPK and NF-κB pathways in ARPE-19 cells. Scientific Reports. 2015.5:14362.DOI:10.1038/srep14362. (通讯作者)
  2. Shijie Zheng, Hongxia Yang, Zihe Chen, Changwei Zheng, Chunyan Lei, Bo Lei. Activation of Liver X Receptor Protects Inner Retinal Damage Induced by N-methyl-D-aspartate. Invest Ophthalmol Vis Sci. 2015; 56(2): 1168-80. (通讯作者)
  3. Sheng X*, Chen X*, Lei B*, Chen R, Wang H, Zhang F, Rong W, Ha R, Liu Y, Zhao F, Yang P, Zhao C. Whole exome sequencing confirms the clinical diagnosis of Marfan syndrome combined with X-linked hypophosphatemia. J Transl Med. 2015;13:179. doi: 10.1186/s12967-015-0534-9.(共同第一作者)
  4. Zheng C, Lei C, Chen Z, Zheng S, Yang H, Qiu Y, Lei B. Topical administration of diminazene aceturate decreases inflammation in endotoxin-induced uveitis. Molecular Vision. 2015;21:403-11. PMID: 25883526 (通讯作者)
  5. Tao XY, Zheng SJ, Lei B. Activated complement classical pathway in a murine model of oxygen-induced retinopathy. International Journal of Ophthalmology. 2015 Feb 18;8(1):17-22. doi: 10.3980/j.issn.2222-3959.2015.01.03. PMID: 25709901(通讯作者)
  6. Du L, Peng H, Wu Q, Zhu M, Luo D, Ke X, Yang P, Lei B. Observation of total VEGF level in hyperglycemia mouse eyes after intravitreal injection of a novel anti-VEGF drug conbercept. Molecular Vision. 2015; 21: 185-193. (通讯作者)
  7. Yang H, Zheng S, Qiu Y, Yang Y, Wang C, Yang P, Li Q, Lei B. Activation of liver X receptor alleviates ocular inflammation in experimental autoimmune uveitis. Invest Ophthalmol Vis Sci. 2014; 55(4): 2795-804. (通讯作者)
  8. Qiu Y, Shil PK, Zhu P, Yang H, Verma A, Lei B, Li Q. Angiotensin-Converting Enzyme 2 (ACE2) Activator DIZE Ameliorates Endotoxin-Induced Uveitis in Mice. Invest Ophthalmol Vis Sci. 2014. 55(6): 3809-18. (共同通讯作者)
  9. Qiu Y, Yang H, Lei B. Effects of three commonly used anesthetics on intraocular pressure in mouse. Current eye research 2014; 39(4): 365-9. (通讯作者)
  10. Hou S, Du L, Lei B, Pang CP, Zhang M, Zhuang W, Zhang M, Huang L, Gong B, Wang M, Zhang Q, Hu K, Zhou Q, Qi J, Wang C, Tian Y, Ye Z, Liang L, Yu H, Li H, Zhou Y, Cao Q, Liu Y, Bai L, Liao D, Kijlstra A, Xu J, Yang Z, Yang P. Genome-wide association analysis of Vogt-Koyanagi-Harada syndrome identifies two new susceptibility loci at 1p31.2 and 10q21.3. Nat Genet. 2014 Sep; 46(9): 1007-11
  11. Lin T, Qiu Y, Liu Y, Mohan R, Li Q, Lei B. (2013) Expressions of adiponectin and its receptors in the retina of human and type 1 diabetes mellitus mouse. Molecular Vision; 19: 1769-1778. (通讯作者)
  12. Zhu Y, Liang L, Qian D, Yu H, Yang P, Lei B, Peng H. (2013) Increase in peripheral blood mononuclear cell Toll-like receptor 2/3 expression and reactivity to their ligands in a cohort of patients with wet age-related macular degeneration. Molecular Vision; 19: 1826-1833. (共同通讯作者)
  13. Lei B. (2012). Rod-driven OFF Pathway Responses in the Distal Retina: Dark-adapted Flicker Electroretinogram in Mouse. PLoS One. 7(8): e43856. doi:10.1371/journal.pone.0043856. (唯一作者)
  14. Mao D, Peng H, Li Q, Wang J, Li P, Hu K, Zhang X, Lei B. (2012). Aqueous Humor and Plasma Adiponectin Levels in Proliferative Diabetic Retinopathy Patients. Current Eye Research. 37(9): 803-8. (通讯作者)