基本情况

张克雄，复旦大学生命科学院副教授。

 

主要经历

2005年至2010年 美国，方向：干细胞生物学与分子治疗

2000年至2005年 复旦大学生命科学院副教授，方向：人体新基因克隆及功能研究

1993年至2000年 复旦大学上海医学院助教、讲师、副教授，方向：医学遗传学

 

研究领域

干细胞生物学与分子治疗

 

论文发表

  1. Kexiong zhang, David J Waxman. High vascularity PC3/2G7 tumors have a greater response to anti-angiogenesis therapy than low vascularity PC3 tumors. Manuscript completed, 2012
  2. Kexiong Zhang, David J Waxman. PC3 prostate tumor-initiating cells with molecular profile FAM65Bhigh/MFI2low/LEF1low increase tumor angiogenesis. Molecular Cancer, 2010; 9: 319
  3. Christine S. Mulvey, Kexiong Zhang, Wei-Han Bobby Liu, David J. Waxman and Irving J. Bigio, "Wavelength-dependent backscattering measurements for quantitative monitoring of apoptosis, Part 1: early and late spectral changes are indicative of the presence of apoptosis in cell cultures", J. Biomed. Opt. 16, 117001, Oct 28, 2011
  4. Christine S. Mulvey, Kexiong Zhang, Wei-Han Bobby Liu, David J. Waxman and Irving J. Bigio, "Wavelength-dependent backscattering measurements for quantitative monitoring of apoptosis, Part 2: early spectral changes during apoptosis are linked to apoptotic volume decrease", J. Biomed. Opt. 16, 117002, Oct 28, 2011
  5. Bingsen Xu, Kexiong Zhang, and Yingqun Huang. Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells. RNA, 2009; 15: 357-361
  6. Kexiong Zhang, QiaoqiaoWang, Yanhua Xie, Gil Mor, Emanuela Sega, Philip S. Low and Yingqun Huang. Receptor-mediated delivery of siRNAs by tethered nucleic acid base-paired interactions. RNA, 2008; 14: 577-583
  7. Tingting Weng, Li Gao, Kexiong Zhang, Manoj Bhaskaran, Deming Fou and Lin Liu. Pleiotrophin regulates alveolar epithelial cell differentiation during fetal lung development. The FASEB Journal, 2007; 21: 941. 4
  8. Tingting Weng, Li Gao, Manoj Bhaskaran, Yujie Guo, Deming Gou, Jeyaparthasarathy Narayanaperumal, Narendranath Reddy Chintagari, Kexiong Zhang and Lin Liu. Pleiotrophin regulates lung epithelial cell proliferation and differentiation during fetal lung development via β-catenin and Dlk1. J. Biol. Chem., 2009; 284 (41): 28021-32
  9. Kexiong Zhang, Rui Gao, Haoxing Zhang, Xin Cai, Chunhua Shen, Chaoqun Wu, Shouyuan Zhao, and Long Yu. Molecular cloning and characterization of three novel lysozyme-like genes, predominantly expressed in the male reproductive system of humans, belonging to the c-type lysozyme/alpha-lactalbumin family. Biology of Reproduction, 2005; 73: 1064–1071
  10. Zhang KX, Yu L, Sun QW, Zhu TF, Saiyin H, Zhou GJ, Wu CQ, Zhao SY. Expression of Cdv-1R gene in mouse epididymis as revealed by in situ hybridization. Systems Biology in Reproductive Medicine, 2005; 51: 7-13
  11. Guangjin Zhou, Jian Wang, Yue Zhang, Chaomin Zhong, Jun Ni, Li Wang, Jinhu Guo, Kexiong Zhang, Long Yu, and Shouyuan Zhao. Cloning, expression and subcellular localization of HN1 and HN1L genes, as well as characterization of their orthologs, defining an evolutionarily conserved gene family. Gene, 2004; 331: 115-123
  12. Keming Du, Kexiong Zhang. The genetic susceptibility of HLA Class II polymorphism to myasthenia gravis. International Journal of Genetics, 2000; 23 (1): 11-13
  13. Keming Du, Kexiong Zhang, Xiuzhen Chen, Ji Zuo, Beili Xia, Zhongshun Hao, Chuanzhen Lu. HLA-DQA1 genetic susceptibility to myasthenia gravis in Han Chinese of Jiangsu, Zhejiang, Shanghai area, Current Immunology, 2000; (6): 365-368
  14. Guanghong Liao, Kexiong Zhang, J Zuo, Daokai Sun, Shuizhen Zhou, Tianlan Chen, Peijuan Jin, Shaozeng Fan. Research on disease relationship between juvenile myasthenia gravis and HLA-DQA1 alleles. Chin J of Pract Pediatr, 2000; 15: 348-350