Personal Information

Wei Yan

Postdoctoral Research Fellow of Johns Hopkins University School of Medicine

 

Research Interests

Stem cell and gene targeting

 

Publications

  1. Yan W, Zhang, H., Wu, M., Inoue, T. and Li, M. Monitoring iodide ion flux through TMEM16a with a new split TEV protease (to be submitted in Feb 2013)
  2. Zhang H, Zou B, Yu H, Moretti A, Wang X, Yan W, Babcock JJ, Bellin M, McManus OB, Tomaselli G, Nan F,Laugwitz KL and Li M (2012) Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channel, Proc. Natl. Acad. Sci. USA 109, 11866-11871
  3. Imanishi M, Imamura C, Higashi C, Yan W, Negi S, Futaki S and Sugiura Y (2010) Zinc finger-zinc finger interaction between the transcription factors, GATA-1 and Sp1, Biochem. Biophys. Res. Commun. 400, 625-630
  4. Jia H, Liu Y, Yan W and Jia J (2009) PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation, Development 136, 307-316
  5. Yan W, Imanishi M, Futaki S and Sugiura Y (2007) α-helical linker of an artificial 6-zinc finger peptide contributes to selective DNA binding to a discontinuous recognition sequence, Biochemistry 46, 8517-8524
  6. Imanishi M, Yan W, Morisaki T and Sugiura Y (2005) An artificial six-zinc finger peptide with polyarginine linker: selective binding to the discontinuous DNA sequences, Biochem. Biophys. Res. Commun. 333, 167-173
  7. Yan W and Cheng L, Correction of the sickle mutation in human iPS cells using TALEN designer nuclease (poster presentation at 5th Annual Meeting of Maryland Stem Cell Research Symposium in Oct 4-5 2012 at Maryland, USA)
  8. Zou B, Yu H, Zhang H, Yan W and Li M, Proteins and heart-when vast chemical diversity meets human cells (poster presentation at 4th Annual Meeting of Maryland Stem Cell Research Symposium in Oct 4-5 2012 at Maryland, USA)
  9. Yan W, Imanishi M, Futaki S and Sugiura Y, The effect of the α-helical linker in an artificial 6-zinc finger peptide on DNA binding (poster presentation at 2nd Annual Meeting of Japanese Society for Chemical Biology in May 9-10 2007 at Kyoto, Japan)
  10. Yan W, Imanishi M, Futaki S and Sugiura Y, The DNA binding of an artificial 6-zinc finger peptide with α helical linker (oral presentation at 127th Annual meeting of the Pharmaceutical Society of Japan in Mar 28-30 2007 at Toyama, Japan)
  11. Yan W, Imanishi M and Futaki S, The distinction of the target DNA phases by an novel 6-zinc finger peptide with α helical linker (poster presentation at 106th Presentation Meeting of Institute for Chemical Research, Kyoto University in Dec 15 2006 at Uji, Japan)
  12. Yan W, Imanishi M, Morisaki T and Sugiura Y, The high selectivity of a novel 6-zinc finger peptide with polyarginine linker (oral presentation at 8th Annual Meeting for Kansai Chinese Association of Life Science in Nov 5 2006 at Nara, Japan)
  13. Imanishi M, Yan W, Futaki S and Sugiura Y, DNA binding properties of multi-zinc finger peptides with artificial linkers (poster presentation at 126th Annual meeting of the Pharmaceutical Society of Japan in Mar 27-30 2006 at Sendai, Japan)
  14. Imanishi M, Yan W, Futaki S and Sugiura Y, The DNA binding of zinc finger peptides with various linker(poster presentation at 4th SORST Joint Symposium in Nov 28-29 2005 at Suita, Japan)
  15. Yan W, Imanishi M, Morisaki T and Sugiura Y, Increase in DNA binding selectivity by introducing polyarginine as the linker of a 6-zinc finger peptide (oral presentation at The International Symposium of Chinese Academy of Science and Engineering in Japan in Oct 29-30 2005 at Fujihakone, Japan)
  16. Imanishi M, Yan W, Morisaki T, Futaki S and Sugiura Y, Selective binding to the discontinuous DNA sequences by an artificial zinc finger peptide with polyarginine linker (poster presentation at Metalloprotein and Protein Design Conference in Jul 28-30 2005 at Chicago, USA)
  17. Yan W, Imanishi M, Morisaki T and Sugiura Y, Increase in DNA binding selectivity by introducing polyarginine as the linker of a 6-zinc finger peptide (poster presentation at 4th International Symposium of the Kyoto COE Project “Elements Science” in Jan 6-7 2005 at Kyoto, Japan)
  18. Yan W, Imanishi M and Sugiura Y, The DNA binding selectivity of an artificial 6-zinc finger peptide with arginine linker (oral presentation at 54th General Meeting of the Kinki Branch of the Pharmaceutical Society of Japan in Oct 23 2004 at Kobe, Japan)
  19. Imanishi M, Yan W and Sugiura Y, The investigation about the DNA binding selectivity of an artificial 6-zinc finger peptide (poster presentation at 14th Symposium on Roles of Metals in Biological Reaction, Biology and Medicine in Jun 10-11 2004 at Shizuoka, Japan)
  20. Yan W, Imanishi M and Sugiura Y, The DNA binding selectivity of an artificial 6-zinc finger peptide with arginine linker (poster presentation at 124th Annual meeting of the Pharmaceutical Society of Japan in Mar 29-31 2004 at Osaka, Japan)