Personal Information
Guangwei Liu, MD, PhD, Professor, Department
of Immunology, Fudan University.
EDUCATION
2004, Ph.D. Jilin University, Changchun,
China Immunology
2001, M.D. Jilin University, Changchun,
China Medicine
TRAINING
2007-2010, Visiting Scholar, Department of
Immunology, St. Jude Children’s Research Hospital, Memphis, TN, USA (Autoimmunity
and Cell Biology)
2004-2006, Post-doc, Institute of Zoology,
Chinese Academy of Sciences, Beijing, China
(Transplant Immunology)
ACADEMIC
APPOINTMENTS
05/2012 – present Professor
Department of Immunology, Fudan University
Shanghai, P.R. China
11/2007 –05/2012 Associate Professor
State Key Laboratory of Biomembrane and
Membrane Biotechnology
Institute of Zoology, Chinese Academy of
Sciences, Beijing, P.R. China
07/2006 – 11/2007 Assistant Professor
State Key Laboratory of Biomembrane and
Membrane Biotechnology
Institute of Zoology, Chinese Academy of
Sciences, Beijing, P.R. China
04/2001 – 07/2004 Lector/Assistant Professor
MH Radiobiology Unit, School of Public
Health
Jilin University, Changchun, P.R. China.
SELECTED
PUBLICATIONS
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Guangwei Liu, Xuelian Hu, Bo Sun, Lianfeng
Zhang, Yong Zhao (2013). Phosphatase Wip1 negatively regulate neutrophil
development and homeostasis through AKT-mTOR. Blood, 121:519-529.
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Guangwei Liu (corresponding author), Yujing
Bi, Hui Yang, Xianghui Wang (2012). Self-eating and self-defense: autophagy
controls innate immunity and adaptive immunity. Journal of Leukocyte Biology,
Dec 27.
-
Guangwei Liu (corresponding author), Hui
Yang (2012). Modulation of macrophage activation and programming in immunity. J
Cell Physiol. Doi: 10. 1002/jcp.24157.
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T.T. Wu, L. Zhang, K.R. Xu, C. Sun , L.
Tong, J. Peng , Guangwei Liu, R.
Wang, and Y. Zhao (2012). Immunosuppressive drugs on
inducing Ag-specific CD4+CD25+Foxp3+ Treg cells during immune response in vivo,
Transplant Immunology, 27: 30-38.
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L.J. Zhang, H.B. Zhang, L.L. Li, Y Xiao,
E.Y. Rao, H.R. Li, Guangwei Liu, Y Zhao (2012). TSC1/2 signaling complex is
essential for peripheral naive CD8+ T cell survival and homeostasis in mice.
Plos One, 7(2): e30592.
-
Bi Y, Guangwei Liu (corresponding author),
R.F. Yang (2011). mTOR regulates T-cell differentiation and activation in
immunity and autoimmunity. Critical Reviews™ in Eukaryotic Gene Expression. 21:
313-322.
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Guangwei Liu, H.X. Ma, Long Li and Y. Zhao
(2011). An instructive role of donor macrophages in mixed chimeras in the
induction of recipient CD4+Foxp3+ Treg cells. Immunology & Cell Biology.
10.1002/jcp. 22891.
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Sun C, Sun L, Ma H, Peng J, Zhen Y, Duan K,
Guangwei Liu, Ding W, Zhao Y (2011). The phenotype and functional alterations
of macrophages in mice with hyperglycemia for long term. J of Cell Physiol.
227: 1670-1679.
-
Bi Y, Guangwei Liu (co-first author), R.F.
Yang (2011). Reciprocal modulation between TH17 and other helper T cell
lineages. J of Cell Physiol. 226: 8-13.
-
Guangwei Liu, H.X. Ma, L Li, and Y. Zhao
(2011). Phenotypic and functional switch of macrophages induced by regulatory
CD4+CD25+T cells in mice. Immunology & Cell Biology. 89: 130-142.
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Guangwei Liu, K. Yang, S. Burns, S.
Shrestha, and H.B. Chi (2010). S1P1- mTOR axis directs the reciprocal
differentiation of Th1 and regulatory T cells. Nature Immunology, 11:
1047-1056.
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Guangwei Liu, L.J. Zhang, and Y. Zhao
(2010). Modulation of immune responses through the direct activation of
Toll-like receptor to T cells. Clinical & Experimental Immunology, 160:
168-175.
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Guangwei Liu, S. Burns, G.H. Huang, K.
Boyd, R.L. Poria, R.A. Flavell, and H.B. Chi (2009). The receptor S1P1
overrides regulatory T cell-mediated immune suppression through Akt-mTOR.
Nature Immunology, 10: 769-777. (See “News and Views” by Ohkura N &
Sakaguchi S. Nat Immunol 10:685-686, 2009; and “Research Highlights,” Nat Rev
Immunol 9:534, 2009).
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Y.J. Bi, Guangwei Liu (corresponding
author), and R.F. Yang (2009). MicroRNAs: novel regulators during the immune
response. J of Cellular Physiology, 218: 467-472.
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H. Shen, G.J. Wu, Guangwei Liu, H.X. Ma,
A.Y. Lian, and Y. Zhao (2009). Effects of Rapamycin on the differentiation and
function of macrophages in vitro. Agricultural Sciences in China. 8: 620-627.
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H.X. Ma, Guangwei Liu, W.J. Ding, Y. Wu, L.
Cai, Y. Zhao (2008). Diabetes-induced immunodeficiency of F4/80+ macrophages: a
study in streptozotocin-induced type 1 diabetic mice. J of Mol Med, 2008, 86:
391-400.
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S.L. Gong, L.H. Dong, Guangwei Liu, P.S.
Gong, W.T. Lu, H.G. Zhao, X.J. Jia, Y. Zhao (2008). Effect of corticosterone,
cAMP, cGMP, Ca2+ and PKC on apoptosis of thymus lymphocyte in vitro in mice
induced by X-irradiation. Biomed and Envir sci. 21:167-72.
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Guangwei Liu, P.S Gong, L.R. Berstein, Y.
J. Bi, S. L.Gong, Cai L (2007). Apoptotic cell death induced by low-dose
radiation in male germ cells: hormesis and adaptation. Crit Rev Toxicol, 37:
587-605.
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Guangwei Liu, H.X. Ma, L.L. Jiang, J.X.
Peng and Y. Zhao (2007). The immunity of normal F4/80+ resident macrophages in
mixed allogeneic chimeras. J of Mol Med, 85: 1125-1135.
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Guangwei Liu, Y. Zhao (2007). Toll-like
receptors and immune regulation: their direct and indirect modulation on
regulatory CD4+CD25+ T cells. Immunology. 122: 149-156.
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L. Zhao, H.J. Wang, L.G. Sun, H.X. Ma,
Guangwei Liu and Zhao Y (2007). The changes of CD4+CD25+ regulatory T cells in
aged mice. J of Leukocyte Biology. 81: 1386-1394. (IF=4.6)
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Y.Y. Qu, B.J. Zhang, L. Zhao, Guangwei Liu,
H. X. Ma, E. Rao, C. Zeng and Zhao Y (2007). The effect of immunosuppressive
drug rapamycin on regulatory CD4+CD25+Foxp3+T cells in mice. Transplant
Immunology, 17: 153-161.
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Guangwei Liu and Y. Zhao (2007). A New
subset of CD4+T cells: Th17 and its immunobiological function. Prog in Biochem
and Biophy, 34: 125-166.
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Guangwei Liu, X.P. Xia, Y. Wu and Y. Zhao
(2006). The macrophage heterogeneity: difference between mouse peritoneal
exudates and splenic F4/80+ macrophages. J of Cell Physiol, 209: 341-352.
(IF=4.5)
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Guangwei Liu, H.X. Ma and Y. Zhao (2006).
The nonopsonic allogeneic cell phagocytosis of macrophages detected by flow
cytometry and two photon fluorescent microscope. Transplant Immunology, 16:
220-226.
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Guangwei Liu, C.L. Wu and Y. Zhao (2006).
Phagocytosis of apoptotic cells and immune regulation. Scand J of Immunol, 64:
1-9.
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Guangwei Liu, Y. Wu, S.L. Gong and Y. Zhao
(2006). Toll-like receptors and graft rejection. Transplant Immunology, 16:
25-31.
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Guangwei Liu, H.X. Ma and Y. Zhao (2007).
Allograft inflammatory factor-1 and transplant reaction. Autoimmunity, 225:
95-102.
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Y.J. Bi, Guangwei Liu (corresponding
author) and R.F. Yang (2007). Th17 cell induction and immune regulatory
effects. J of Cell Physiol, 211: 273-278.
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Guangwei Liu, P.S. Gong, H.G. Zhao, Z.C.
Wang, S.L. Gong and L. Cai (2006). Effect of low-level radiation on male germ
cell death. Radiation Research, 165: 379–389.
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Y. Zhao and Guangwei Liu (2006). Specific
immune tolerance of antigen- presenting cells: Hypothesis and significance.
Medical Hypotheses. 20: 201-204.
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S.L. Gong, G. Zhao, H.G. Zhao, W.T. Lu,
Guangwei Liu and P. Zhu (2004). Ability of luteinizing hormone releasing
hormone-Pseudmonas aeruginosa exotoxin 40 binding to LHRH receptor on human
liver cancer cells. World Journal of Gastroenterology, 10: 2870-2873.