基本情况
章晓波，1965年8月12日生，获中国科技大学博士学位，曾任新加坡国立大学博士后研究员。现任浙江大学生命科学学院教授，博士生导师。2003年回国后任国家海洋局第三海洋研究所研究员，2007年调入浙江大学，任浙江大学生命科学学院特聘教授。国家杰出青年科学基金获得者（2005年度），入选国家新世纪百千万人才工程（2006年度），享受政府特殊津贴，获省部级一等奖二项（均为第一完成人）。中国海洋学会海洋生物工程专业委员会常务委员，中国微生物学会海洋微生物专业委员会委员，中国水产学会第8届理事，中国水产学会鱼病专业委员会委员，中国水产学会生物技术专业委员会委员，国家自然科学基金委员会第12届、第13届专家评审组专家，中国大洋协会国际海底生物及其基因资源工作组专家。主要从事对虾病毒的分子生物学及病毒与宿主的相互作用、对虾抗病毒及其天然免疫、深海嗜热噬菌体的分子生物学等研究工作。主持承担了国家杰出青年科学基金、国家自然科学基金、国家“863”计划、中国大洋矿产资源研究开发协会等多个科研课题。2005年获“国家杰出青年科学基金”。
研究领域
主要从事海洋生物病毒感染应激反应与细胞异常增殖的研究
论文发表
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Wenlin Wu, Rongrong Zong, Jianyang Xu, Xiaobo Zhang*. 2008. Antiviral
phagocytosis is regulated by a novel Rab-dependent complex in shrimp Penaeus
japonicus. The Journal of Proteome Research, 7: 424-431
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Weifeng Liu, Fang Han, Xiaobo Zhang*. 2009. Ran
GTPase regulates hemocytic phagocytosis of shrimp by interaction with myosin.
The Journal of Proteome Research, 8: 1198-1206
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Dahai Wei, Xiaobo Zhang*. 2010. Proteomic analysis of interactions between
a deep-sea thermophilic bacteriophage and its host at high temperature. Journal
of Virology, 84: 2365-2373
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Hebin Li, Xinglai Ji, Zhidong Zhou, Yiqian Wang,
Xiaobo Zhang*. 2010. Thermus thermophilus proteins that are differentially
expressed in response to growth temperature and their implication in
thermoadaptation. The Journal of Proteome Research, 9: 855- 864
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Yaodong He, Xiaobo
Zhang*.
2012. Comprehensive
characterization of viral miRNAs involved in white spot syndrome virus (WSSV)
infection. RNA Biology, 9:
1-11
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Tianzhi Huang, Xiaobo Zhang*. 2012. Functional
analysis of a crustacean microRNA in host-virus interactions. Journal of
Virology, 86: 12997–13004
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Ting Ye, Wen Tang, Xiaobo Zhang*. 2012. Involvement of Rab6 in the regulation of
phagocytosis against virus infection in invertebrates. The Journal of Proteome Research, 11:
4834-4846
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Tianzhi
Huang, Xiaobo Zhang*. 2013. Host defense against DNA virus infection in shrimp
is mediated by the siRNA pathway. European Journal of Immunology, 43: 137-146
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Fei Zhu,
Xiaobo Zhang*. 2013. The Wnt signaling pathway is involved in the regulation of
phagocytosis of virus in Drosophila. Scientific Reports, 3(2069): 1-9
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Yaodong
He, Kai Yang, Xiaobo Zhang*. 2014.
Viral microRNAs targeting virus genes promote virus infection in shrimp in vivo. Journal of Virology, 88(2): 1104–1112
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Tianzhi
Huang, Yalei Cui, Xiaobo Zhang*. 2014. Involvement
of viral microRNA in the regulation of antiviral apoptosis in shrimp. Journal
of Virology, 88(5): 2544-2554
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Min Jin,
Yanjiang Chen, Chenxi Xu, Xiaobo Zhang*. 2014. The effect of inhibition of host
MreB on the infection of thermophilic phage GVE2 in high temperature
environment. Scientific Reports, 4(4823): 1-8
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Geng Yang, Yi Gong, Qizhi Wang, Yumeng
Wang, Xiaobo Zhang*. 2015. The role of miR-100-mediated Notch pathway in
apoptosis of gastric tumor cells. Cellular Signalling, 27: 1087-1101
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Yulei Chen, Chunxia Jiang, Min Jin, Yi Gong, Xiaobo Zhang*.
2015. The role of Rab6 GTPase in the maturation of phagosome against Staphylococcus
aureus. The International Journal of Biochemistry & Cell Biology, 61: 35-44
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Yi Gong,
Tianliang He, Lu Yang, Geng Yang, Yulei Chen, Xiaobo Zhang*. 2015. The role
of miR-100 in regulating apoptosis of breast cancer cells. Scientific Reports, 5: 11650, doi: 10.1038/srep11650