PERSONAL INFORMATION

HuangXiuyan, associate chief physician, associate professor, Department of general surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital.

 

EDUCATION

2014–2015 Dana-Farber Cancer Institute (DFCI), Brigham and Women’s Hospital (BWH) of Harvard Medical, School (HMS) affiliated to Harvard University, Division of Surgical Oncology, Postdoctoral Fellow

2003–2008 Zhong shan Hospital, Medical College of Fudan University, liver surgery, MD

 

HONORS AND AWARDS

2016 Outstanding employee, Shanghai 6th People’s Hospital, Shanghai Jiao Tong University

2013 Outstanding employee, Shanghai 6th People’s Hospital, Shanghai Jiao Tong University

2010 Excellent surgical chief resident, Shanghai 6th People’s Hospital, Shanghai Jiao Tong University

2008 Advanced individual of college students’ social practice in Shanghai

 

RESEARCH EXPERIENCE

Jan 2016 – current “The International Foundation of Translational Medicine for Abroad Scholars and Students, U.S. and China” (No. UCTMP2015-03C001).

Jan 2013 – 2016 “Intervention and molecular mechanism underlying the interaction effect between MIM-B and Caveolin-1 on EGFR endocytic cycle in hepatocellular carcinoma” (NSFC 81272401) granted by the National Natural Science Foundation of China.

Jan 2011 – Dec 2012 “Basic research of in vivo inhibitive efficacy of substances of Chinese herbal compound Songyou Yin on human hepatocellular carcinoma” (2010L059A) granted by Shanghai Municipal Health Bureau, China.

Jan 2010 – Dec 2011 “Effect of MIM-B on invasive potential of hepatocellular carcinoma in vitro and in vivo” (Hospital-1131) granted by Shanghai 6th People’s Hospital, China.

2005 – 2008 “The effect of palliative liver resection on invasive and metastatic potential of residual hepatocellular carcinoma”, the State Key Basic Research Program of China grants 2004CB518700, China.

Part of Involved Research Program:

Jan 2013 – Dec 2014 “Optimization of Chinese herbal compound Songyou Yin and MRI assessment” (2012QJ001A) funded by Shanghai Municipal Health Bureau, China.

Jan 2006 – Dec 2008 “Resistance and molecular mechanisms of autophagy of cell lines of hepatocellular carcinoma with high metastatic potential” (30571801) funded by the National Natural Science Foundation of China.

Jan 2006 – Dec 2008 “The relationship between the hepatic sinus blood capillary and the rejection after liver transplantation” (30500472) funded by the National Natural Science Foundation of China.

Jan 2006 – Dec 2008 “Protein molecular markers for micro portal venous tumor emboli of hepatocellular carcinoma” (30600605) funded by the National Natural Science Foundation of China.

Jun 2010 – May 2012 “Molecular biological compatibility study of Biodegradable magnesium alloy with bile duct epithelial cell” (YG2010MS45) funded by Shanghai Jiao Tong University, China.

 

WORK EXPERIENCE

2013 – current Associate chief physician The Shanghai 6th People’s Hospital, Shanghai Jiao Tong University

2011 – 2012 Attending The Shanghai 6th People’s Hospital, Shanghai Jiao Tong University

2010 – 2011 Chief resident The Shanghai 6th People’s Hospital, Shanghai Jiao Tong University

2008 – 2009 Surgical resident and chief resident training The Shanghai 6th People’s Hospital, Shanghai Jiao Tong University

2003 – 2008 Surgical resident and chief resident training The Zhongshan Hospital, Fudan Universsity

1999 – 2002 Surgical resident The 6th People’s Hospital, Wuhu City, China

 

PUBLICATIONS IN RECENT YEARS（2009-2014）

Co-first Author

1       The chemokine CXCL9 expression is associated with better prognosis for colorectal carcinoma patients [J]. Biomed Pharmacother, 2016, 8: 8–13.

2       Distribution of lymphocyte subpopulations in thyroid glands of human autoimmune thyroid disease. J Clin Lab Anal, 2014, 28 (3): 249–254.

3       Cancer targeting gene-viro-therapy for pancreatic cancer using oncolytic adenovirus ZD55-IL-24 in immune-competent mice. Mol Bio Rep, 2013, 40 (9): 5397–5405.

First Author

1       Comprehensive circular RNA profiling reveals the regulatory role of the circRNA-100338/miR-141-3p pathway in hepatitis B-related hepatocellular carcinoma. Sci Rep, 2017, 7 (1): 5428.

2       Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2). J Exp Clin Cancer Res, 2017, 36(1): 107.

3       Missing-in-metastasis MIM-B combined with caveolin-1 promotes the metastatic potential of hepatocellular carcinoma. Oncotarget, 2017.7.18, under production.

4       Interaction between missing in metastasis B and caveolin-1 in hepatocellular carcinoma. Chin J Exp Surg, 2017, 34 (6): 963–969.

5       Pancreatic cancer cell-derived IGFBP-3 contributes to muscle wasting [J]. J Exp Clin Cancer Res, 2016, 35: 46.

6       Elevated MTSS1 expression associated with metastasis and poor prognosis of residual hepatitis B-related hepatocellular carcinoma [J]. J Exp Clin Cancer Res. 2016, 35(1):85.

7       A case of multiple primary malignancies and investigation of family history. Oncol Lett, 2012, 4(5), 931–934.

8       Herbal compound Songyou Yin reinforced interferon–Alfa to inhibit the enhanced metastatic potential induced by palliative resection of hepatocellular carcinoma in nude mice. BMC Cancer, 2010, 10, 580.

9       Effects of the dysregulation in Hedgehog–Gli singnaling pathway on the growth and metastatic potential of human hepatocellular carcinoma, and its advances of molecular targeted therapy. U.S Chinese J of Lymphology and Oncology, 2010, 9 (2): 49–53.

10    Role of MIM/MIM–B in human tumor progression. U.S Chinese J of Lymphology and Oncology, 2010, 9 (3): 104–108.

11    Herbal compound extract Songyou Yin inhibits tumor growth and prolongs survival in nude mice bearing human hepatocellular carcinoma xenograft with high metastatic potential. J Cancer Res Clin Oncol, 2009, 135 (9): 1245–1255.

12    The experimental research on the apoptosis of hepatocellular carcinoma induced by Chinese herbal compound Songyou Yin. Chinese Archives of Traditional Chinese Medicine, 2014, 32 (2): 249–251.

13    A case with rectal cancer relapse after clinical complete remission after neoadjuvant chemoradiotherapy. Chin J Clinicians (Electronic Edition), 2013, 7(17): 8079–8081.

14    Preliminary research on effective substances of Chinese herbal compound Songyou Yin in vivo. Chinese Archives of Traditional Chinese Medicine, 2013, 31 (5): 979–983.

15    Establishment of metastatic molecule diagnostic model for hepatocellular carcinoma. Chin J Exp Surg, 2013, 30 (5): 1072–1074.

16    Establishment of a high metastatic potential human hepatocellular carcinoma orthotopic transplantation model with palliative liver resection in nude mice. Chin J Hepatol, 2013, 21 (8): 604–608.

17    Experimental research on the enhanced invasive potentials of human hepatocelluar carcinoma following palliative resection. Chin J Clinicians (Electronic Edition), 2011, 5 (2): 479–481.

18    In vitro inhibitory effect of sorafenib on proliferation of human hepatocellular carcinoma cells with differential pERK expression reinforced by lentivirus-mediated small RNA interference targeting MIM-B gene. Chin J Exp Surg, 2011, 28 (2): 396–398.

19    Experimental research on inhibition of interferon-alfa on hepatocellular carcinoma reinforced by Chinese herbal compound Songyou Yin. CJTCMP, 2011, 26 (12): 2859–2861.

20    Analysis of the Effects of Chinese Herbal Compound Songyou Yin in vitro and in vivo. Chinese Archives of Traditional Chinese Medicine, 2011, 29 (11): 2542–2544.

21    Experimental observation of the effects of Chinese herbal compound Songyou Yin combined with interferon–alpha on the growth and metastasis of residual hepatocellular carcinoma in nude mice model of palliative resection. J Clini Hepatol, 2011, 27 (5): 482–484.

22    A case with multiple primary malignancies. Chin J Med Genet, 2011, 28 (4): 471–472.

23    Inhibition effects of Chinese herbal compound prescription of Songyouyin on orthotopic tumor in nude mice bearing human hepatocellular carcinoma xenografts with high metastatic potential. CJTCMP, 2010, 25 (2): 234–237.

24    Role of proteins of missing in metastasis in cancer initiation and progression. Tumor, 2010, 30 (2): 170–172.

25   Effects of Hedgehog–Gli singnaling pathway in hepatocellular carcinoma. Chin J Cancer Prev Treat, 2010, 17 (6): 471–474.

26    Experimental observation on the alteration of metastatic potential and its gene function net of residual hepatocellular carcinoma following palliative liver resection. Natl Med J China, 2010, 90 (18): 1278–1282.

27    The criteria of hepatectomy for hepatocellular carcinoma and its clinical significance. Chinese Journal of Clinical Oncology, 2010, 37 (9): 533–535.

28    Study on fingerprints of Chinese herbal compound Songyou Yin and its component extracts by high performance liquid chromatograpy. Chinese Archives of Traditional Chinese Medicine, 2010, 28 (7): 1389–1392.

29    Experimental research on inhibition effects of Chinese herbal compound Songyou Yin on tumor growth and metastasis of residual hepatocellular carcinoma following palliative liver resection. CJTCMP, 2010, 25 (12): 1988–1990.

30    The Experimental research on the in vitro inhibitory effects of medicated serum with Chinese herbal compound Songyou Yinon human hepatocellular carcinoma MHCC97H cells with high metastatic potential. Chinese Archives of Traditional Chinese Medicine, 2010, 28 (11): 2396–2398.

31    Effects of MIM-B gene on invasive and metastatic potentials of human hepatoceHuar carcinoma MHCC97Hcells. Chin J Hepatol, 2010, 18 (12): 914–918.

Corresponding Author

1       Preliminary Research on Formula Optimization of Chinese Herbal Compound Songyou Yin. Chinese Archives of Traditional Chinese Medicine, 2015, 33 (11): 2613–2616

2       Evaluation of a new mark-pen in preoperative application for patients with varicose vein of lower extremity. Hebei Medical Journal, 2013, 35 (19): 2885–2887.

3       Risk factors for psychiatric symptoms after liver transplantation. Chin J Misdiagn, 2011, 11 (19): 4537–4538.

4       Identification and treatment for patients with psychonosema following liver transplantation. Chin J Transplant (Electronic Edition), 2010, 4 (3): 229–231.

5       Research advance on anti-tumor effects and mechanisms of Traditional Chinese Medicine. Medical Recapitulate, 2010, 16 (3): 386–389.

6       A case of spontaneous subdural hematoma falx. Chin J Misdiagn, 2010, 10 (4): 993.