基本情况

李剑利，理学博士，教授、博士生导师，现任西北大学教务处处长，兼任陕西省化学会副秘书长、陕西省高等教育学会副秘书长，2015年入选“陕西省中青年科技创新领军人才支持计划”。


研究领域

仿生有机化学、有机合成新反应和新方法、功能有机分子的设计合成及应用、有机能源化学研究 


教育背景

2012年1月至4月 访问学者，法国斯特拉斯堡大学 

2007年至2011年 博士后，西北大学生命科学学院

2002年至2007年 博士，西北大学化学系

1993年至1997年 学士，西北大学化学系


工作经历

1997年至今 西北大学从事教学与科研工作 


科研项目与获奖情况

主持研究项目：国家自然科学基金面上项目（No.21572177；21272184；20972124）3项；中国博士后科学基金面上项目（No.20080441180）1项；陕西省科技统筹创新工程重大项目预研项目（No.2011K12-77）1项；陕西省自然科学基金重点项目（No.2015JZ003）1项、面上项目（No.2007B04）1项；陕北能源化工基地建设C1化学专项研究子课题1项、生态修复惠民工程子项目1项；陕西省教育厅自然科学基金专项（No.12JK0584；08JK456）2项；西安市科技攻关项目（No.CXY1429-6；CXY1123-1）2项；西北大学自然科学研究基金项目（No.05NW45）1项，以及陕西省教学改革研究重点项目（No.13BZ21）等多项教研项目。

获奖情况：国家教学成果奖二等奖1项；陕西省教学成果奖特等奖1项；陕西省科学技术奖壹等奖1项、叁等奖1项；陕西省高等学校科学技术奖壹等奖1项、贰等奖1项；2008-2011连续4届指导大学生国家级创新性实验计划项目获优秀；指导学生获“挑战杯”课外学术科技作品竞赛2011年校级、省级特等奖，2013年省级壹等奖、全国三等奖，个人荣获第十三届“挑战杯”全国大学生课外学术科技作品竞赛“优秀指导教师奖”。


论文发表

近年来，以第一作者或通讯作者先后在《Organic Letters》《Journal of Organic Chemistry》《Analytical Chemistry》《Inorganic Chemistry》《Scientific Reports》《Chemistry–An Asian Journal》《Analytica Chimica Acta》《European Journal of Organic Chemistry》《Sensors and Actuators B:Chemical》《Dyes and Pigments》《RSC Advances》《Tetrahedron》《Tetrahedron Letters》《Synthesis》《Journal of Luminescence》《Chinese Chemical Letters》《Chinese Journal of Chemistry》《高等学校化学学报》等国内外权威学术期刊发表研究论文60余篇，国家授权发明专利13项，国家受理发明专利10项。

近期代表性论文：

  1. Xilang Jin; Shaoping Wu; Mengyao She; Yifan Jia; Likai Hao; Bing Yin; Lanying Wang; Martin Obst; Yehua Shen; Yongmin Zhang; Jianli Li*. Novel Fluorescein-Based Fluorescent Probe for Detecting H2S and Its Real Applications in Blood Plasma and Biological Imaging. Analytical Chemistry, 2016, 88, 11253-11260
  2. Mengyao She; Zheng Yang; Likai Hao; Zhaohui Wang; Tianyou Luo; Martin Obst; Ping Liu; Yehua Shen; Shengyong Zhang; Jianli Li*. A novel approach to study the structure-property relationships and applications in living systems of modular Cu2+fluorescent probes.Scientific Reports, 2016, |6:28972| DOI:10.1038/srep28972
  3. Zheng Yang; Mengyao She; Siyue Ma; Bing Yin; Ping Liu; Xiangrong Liu; Shunsheng Zhao; Jianli Li*. Rhodamine based guanidinobenzimidazole functionalized fluorescentprobe for tetravalent tin and its application in living cells imaging. Sensors and Actuators B: Chemical, 2016, DOI:10.1016/j.snb.2016.09.170
  4. Yuelu Zhu; Cheng Li; Jidong Zhang; Mengyao She; Wei Sun; Kerou Wan; Yaqi Wang; Bin Yin; Ping Liu; Jianli Li*. A Facile FeCl3/I2‑Catalyzed Aerobic Oxidative Coupling Reaction:Synthesis of Tetrasubstituted Imidazoles from Amidines and Chalcones. Organic Letters, 2015, 17, 3872-3875
  5. Hongmei Li; Cuiling Wang; Mengyao She; Yuelu Zhu; Jidong Zhang; Zheng Yang; Ping Liu*; Yaoyu Wang; Jianli Li*. Two rhodamine lactam modulated lysosome-targetable fluorescence probes for sensitively and selectively monitoring subcellular organelle pH change. Analytica Chimica Acta, 2015,900, 97-102
  6. Chen Li; Bing Yin; Yifan Kang; Ping Liu*; Liang Chen; Yaoyu Wang; Jianli Li*. Mixed Ligand CuIIN2O2 Complexes:Biomimetic Synthesis,Activities in Vitro and Biological Models, Theoretical Calculations. Inorganic Chemistry, 2014,53,13019-13030
  7. Zheng Yang; Mengyao She; Bing Yin; Likai Hao; Martin Obst; Ping Liu*; Jianli Li*. Solvent-dependent turn-on probe for dual monitoring of Ag+and Zn2+in living biological samples. Analytica Chimica Acta, 2015, 868, 53-59
  8. Xilang Jin; Likai Hao; Mengyao She; Martin Obst; Andreas Kappler; Bing Yin; Ping Liu;Jianli Li*; Lanying Wang; Zhen Shi. Visualizing tributyltin(TBT)in bacterial aggregates by specific rhodamine-based fluorescent probes. Analytica Chimica Acta, 2015, 853, 514-520
  9. Chen Li; Haixia Ge; Bing Yin; Mengyao She; Ping Liu; Xiangdong Li; Jianli Li*. Novel 3,6-unsymmetrically  disubstituted-1,2,4,5-tetrazines:S-induced one-pot synthesis,properties and theoretical study. RSC Advances, 2015, 5, 12277-12286
  10. Siyue Ma; Zheng Yang; Mengyao She; Wei Sun; Bing Yin; Ping Liu; Shengyong Zhang; Jianli Li*. Design and synthesis of functionalized rhodamine based probes for specific intracellular fluorescence imaging of Fe3+. Dyes and Pigments, 2015, 115, 120-126
  11. Cheng Li; Shujuan An; Yuelu Zhu; Jin Zhang; Yifan Kang; Ping Liu; Yaoyu Wang; Jianli Li*. Copper-catalyzed intermolecular cyclization of nitriles and 2-aminobenzylamine for 3,4-dihydroquinazolines and quinazolines synthesis via cascade coupling and aerobic oxidation. RSC Advances, 2014, 4, 49888-49891
  12. Zheng Yang; Likai Hao; Bing Yin; Mengyao She; Martin Obst; Andreas Kappler; Jianli Li*. Six-Membered Spirocycle Triggered Probe for Visualizing Hg2+in Living Cells and Bacteria-EPS-Mineral Aggregates. Organic Letters, 2013, 15(17), 4334-4337
  13. Li Xiangnan; Li Cheng; Yin Bing; Li Cong; Liu Ping; Li Jianli*; Shi Zhen. DDQ-Induced Dehydrogenation on Heterocycles for C-C Double Bond Formation:Synthesis of 2-Thiazoles and 2-Oxazoles. Chemistry–An Asian Journal, 2013, 8, 1408-1411
  14. Shujuan An; Bing Yin; Ping Liu; Xiangnan Li; Chen Li; Jianli Li*; Zhen Shi. Microwave-Assisted Cascade Cycloaddition for C-N Bond Formation: An Approach to the Construction of 1,4,5,6-Tetrahydropyrimidine and 2-Imidazoline Derivatives. Synthesis, 2013, 45, 2525-2532
  15. Zheng Yang; Mengjia Wang; Mengyao She; Bing Yin; Yangyang Huang; Ping Liu; Jianli Li*; Shengyong Zhang. New aliphatic and aromatic dialdehyde bridged turn-on probes forhypochlorite detection in biological samples based on bis(fluorescein). Sensors and Actuators B: Chemical, 2014, 202, 656-662
  16. Wei Sun; Zhao-Hui Wang; Meng-Yao She; Zheng Yang; Xi-Lang Jin; Ya-Qi Wang; Zhen Shi; Jian-Li Li*. Study on the inclusion behavior and solid inclusion complex of 5-amino-6-methyl-2-benzimidazolone with cyclodextrins. Chinese Chemical Letters, 2016, 27, 1077-1082
  17. Yang-Yang Huang; Meng-Jia Wang; Zheng Yang; Meng-Yao She; Shu Wang; Ping Liu*; Jian-Li Li*; Zhen Shi. High efficient probes with Schiff base functional receptors for hypochlorite sensing under physiological conditions. Chinese Chemical Letters, 2014, 25, 1077-1081
  18. Yanning Shi; Xilang Jin; Yechen Hu; Shuli Wang; Jianli Li*; Zhen Shi. Synthesis, characterization of bis[2-(1H-benzi midazol-2-yl)benzoa-to]nickel(II), and its application in the formation of dimethyl carbonate from methanol and CO2. Research on Chemical Intermediates, 2014, 40(3): 1179-1186
  19. Xilang Jin; Likai Hao; Yanling Hu; Mengyao She; Yanning Shi; Martin Obst; Jianli Li*; Zhen Shi. Two novel fluorescein-based fluorescent probes for hypochlorite andits real applications in tap water and biological imaging. Sensors and Actuators B:Chemical, 2013, 186, 56-60
  20. She Mengyao; Xiao Dawei; Yin Bing; Yang Zheng; Liu Ping; Li Jianli*; Shi Zhen. An efficiently cobalt-catalyzed carbonylative approach to phenylacetic acid derivatives. Tetrahedron, 2013, 69: 7264-7268
  21. Zheng Yang; Mengyao She; Jin Zhang; Xiaoxiang Chen; Yangyang Huang; Hengyan Zhu;Ping Liu; Jianli Li*; Zhen Shi. Highly sensitive and selective rhodamine Schiff base“off-on”chemosensors for Cu2+ imaging in living cells. Sensors and Actuators B: Chemical, 2013, 176, 482-487
  22. Ge Haixia; Liu Ping; Li Xiangnan; Sun Wei; Li Jianli*; Yang Bingqin; Shi Zhen.S-Co(II)cascade catalysis:cyclocondensation of aromatic nitriles with alkamine. Tetrahedron, 2013, 69, 6591-6597
  23. Likai Hao*; Jianli Li; Andreas Kappler; Martin Obst. Mapping of heavy metal ion sorption to cell-extracellular polymeric substance-mineral aggregates by using metal-selective fluorescent probes and confocal laser scanning microscopy. Applied and Environmental Microbiology, 2013, 79, 6524-6534
  24. Yang Zheng; She Mengyao; Yin Bing; Cui Jihong; Zhang Yuze; Sun Wei; Li Jianli*; Shi Zhen. Three rhodamine-based"off-on"chemosensors with high selectivity and sensitivity for Fe3+imaging in living cells. Journal of Organic Chemistry, 2012, 77(2), 1143-1147
  25. Li Xiangnan; Zhou Baoyue; Zhang Jin; She Mengyao; An Shujuan; Ge Haixia; Li Cong; Yin Bing; Li Jianli*; Shi Zhen. Solvent-free tandem synthesis of 2-thiazolines and 2-oxazolines catalyzed by acopper catalyst. European Journal of Organic Chemistry, 2012, (8), 1626-1632
  26. She Mengyao; Yang Zheng; Yin Bing; Zhang Jin; Gu Jia; Yin Wenting; Li Jian-li*, Zhao Guifang; Shi Zhen. A novel rhodamine-based fluorescent and colorimetric"off-on"chemosensor and investigation of the recognizing behavior towards Fe3+. Dyes and Pigments, 2012, 99(3), 1337-1343
  27. Yin Wenting; Cui Hao; Yang Zheng; Li Chen; She Mengyao; Yin Bing; Li Jian-li*; Zhao Guifang; Shi Zhen. Facile synthesis and characterization of rhodamine-based colorimetric and“off–on”fluorescent chemosensor for Fe3+. Sensors and Actuators B: Chemical, 2011, 32(9), 2046-2061
  28. Xianglong Wu; Xilang Jin; Yunxia Wang; Qibing Mei; Jianli Li*; Zhen Shi*. Synthesis and Spectral Properties of Novel Chlorinated Ph Fluorescent Probes. Journal of Luminescence, 2011, 131, 776-780
  29. Zhang Jin; Wang Xiao; Yang Meipan; Wan Kerou; Yin Bing; Wang Yunxia; Li Jianli*; Shi Zhen. Copper-catalyzed synthesis of 2-imidazolines and their N-hydroxyethyl derivatives under various conditions. Tetrahedron Letters, 2011, 157(2), 675-680
  30. Zhang Bin; Li Jianli*; Chen Wei; Wang Yunxia; Shi Zhen. Synthesis, crystal structure of Co(II)(6-methoxybenzothiazole-2-carboxylate)2(DMF)2 and its application to carbonylation of benzyl chloride. Chinese Journal of Chemistry, 2010, 28(1), 111-114
  31. Xiao Dawei; Zhang Bin; Li Jianli*; Shi Zhen. Synthesis and characterization of anew ligand 2-(4,5-dihydro-2-thiazolyl)-6-methoxylbenzothiazole and its dinuclear Co(II)complex. Chinese Journal of Structural Chemistry, 2010, 29(11), 1712-1716
  32. 黄阳阳，王梦嘉，厍梦尧，杨征，刘萍，李剑利*，史真，基于氧杂蒽结构可控官能化的荧光探针研究新进展，有机化学，2014，34（1），1-25 （本期封面文章）
  33. 周葆悦，张金，李向南，厍梦尧，张劲，李剑利*，史真，2-咪唑啉类化合物的合成及应用研究新进展，有机化学，2013，33（3），423-435 （本期封面文章）
  34. 李晨，杨征，厍梦尧，尹文婷，李剑利*，赵桂仿，史真，超氧化物歧化酶化学模拟的新进展，高等学校化学学报，2011，32（9），2046-2061
  35. 李娜，刘美玲，尹文婷，杨征，李剑利*，史真，罗丹明基“OFF-ON”型荧光探针研究的一些新进展，有机化学，2011，31（1），39-53
  36. 李剑利，尹文婷，张金，郭媛，武祥龙，白银娟，史真*，环己基甲酮类化合物的仿生合成方法研究，高等学校化学学报，2008，29（1），100-103