基本情况

张俊波，理学博士，北京师范大学化学学院教授、博士生导师，副院长。


研究领域

主要从事单光子发射（SPECT）和正电子发射（PET）诊断药物以及放射性治疗药物的设计合成以及开发应用研究，其中以新型心、脑、肿瘤以及炎症等放射性分子探针为重点研究目标


论文发表

  1. Shijian Zhang, Weifang Zhang, Yue Wang,Zhonghui Jin, Xuebin Wang, Junbo,Zhang*, Yanyan Zhang*. Synthesis and biodistribution of a novel 99mTcN complex of norfloxacin dithiocarbamate as a potential agent for bacterial infection imaging. Bioconjugate Chemistry, 2011, 22: 369-375
  2. Junbo Zhang*, Shijian Zhang, Haixun Guo, XueBin Wang. Synthesis and biological evaluation of a novel 99mTc(CO)3 complex of ciprofloxacin dithiocarbamate as a potential agent to target infection. Bioorganic & Medicinal Chemistry Letters, 2010, 20, 3781-3784
  3. Junbo Zhang*, Xiao Lin, Jialei Ren, Jing Liu, XueBin Wang. Synthesis and biodistribution of a novel 99mTc nitrido dithiocarbamate complex containing aromatic group for cerebral imaging. Applied Radiation and Isotopes, 2010, 68, 101-104
  4. Junbo Zhang*, Qian Yu, Jinfeng Huo, Yan Pang, Sheng Yang, Yining He, Tingting Tang, Chenchen Yang, Xuebin Wang. Synthesis and biodistribution of a novel Tc-99m-DMSA-metronidazole ester as a potential tumor hypoxia imaging agent. Journal of Radioanalytical and Nuclear Chemistry, 2010, 283(2), 481-485
  5. Junbo Zhang*, Jialei Ren, Xiao Lin, XueBin Wang. Synthesis and biological evaluation of a novel 99mTc nitrido radiopharmaceutical with deoxyglucose dithiocarbamate, showing tumor uptake. Bioorganic & Medicinal Chemistry Letters, 2009, 19(10), 2752-2754
  6. Junbo Zhang*, ZhiXin Song, Jinfeng Chu, XueBin Wang. Synthesis and biodistribution of a novel [99mTcN(PNP5)( DMCHDTC)]+ complex as a potential myocardial perfusion imaging agent. Applied Radiation and Isotopes, 2009,67, 1661-1663
  7. Junbo Zhang*, Yan Lin, Xi Sheng, XueBin Wang. Synthesis of a novel 99mTc nitrido radiopharmaceutical with isopropyl xanthate, showing brain uptake. Applied Radiation and Isotopes, 2009, 67, 79-82
  8. JunBo Zhang,* ZhiXin Song, XueBin Wang. Synthesis of a bis(2, 3-dimethylcyclohexyldithiocarbamato)  nitrido 99mTc complex: a potential tracer for myocardial imaging. Applied Radiation and Isotopes, 2009, 67, 577-580
  9. JunBo Zhang,* Gang Luo, XueBin Wang. Synthesis and biodistribution of a novel 99mTc nitrido dithiocarbamate complex containing ether group as a potential myocardial and brain imaging agent. Journal of Radioanalytical and Nuclear Chemistry, 2009, 279(3), 783-785
  10. Junbo Zhang *, Haixun Guo, Shijian Zhang, Yan Lin, Xuebin Wang. Synthesis and biodistribution of a novel 99mTcN complex of ciprofloxacin dithiocarbamate as a potential agent for infection imaging., Bioorganic & Medicinal Chemistry Letters, 2008, 18, 5168-5170
  11. Haixun Guo, Junbo Zhang*, Zhiwei Ma, Xuebin Wang. Synthesis and biodistribution of 99mTcN-isopentyl xanthate as a potential myocardial perfusion imaging agent. Journal of Radioanalytical and Nuclear Chemistry, 2008, 275(1), 121-123
  12. Junbo Zhang*, TianJun Yu, ZhongFang Wang, Yan Lin, Fang Wen, MiaoMiao Xing, XueBin Wang. Synthesis and biodistribution of two novel 99mTc nitrido dithiocarbamate complexes containing heterocyclic linkage as potential brain perfusion imaging agents. Journal of Radioanalytical and Nuclear Chemistry, 2007, 274(1), 195-197
  13. Junbo Zhang*, Xuebin Wang, Can Jin. Synthesis and biodistribution of the 99mTc(CO)3-DEDT complex as a potential new radiopharmaceutical for brain imaging. Journal of Radioanalytical and Nuclear Chemistry, 2007, 272(1), 91-94
  14. Junbo Zhang*, Xuebin Wang, ChunJun Tian. Synthesis of a bis-(N-butyl-dithiocarbamato)-nitrido 99mTc complex: a potential new brain imaging agent. Journal of Radioanalytical and Nuclear Chemistry, 2007, 273(1), 15-17
  15. Junbo Zhang*, Xuebin Wang, Can Jin.Synthesis of 99mTc(CO)3-NOET via [99mTc(OH2)3(CO)3]+ precursor and comparative biological studies with 99mTcN-noet. Journal of Radioanalytical and Nuclear Chemistry, 2006, 269(1), 227-230
  16. Junbo Zhang*, Xuebin Wang, Jing Liu. Synthesis of a bis-(N-sec-butyl-dithiocarbamato)-nitrido-99mTc complex: a potential new radiopharmaceutical for brain perfusion studies. Applied Radiation and Isotopes, 2005, 62:33-37
  17. Junbo Zhang*, Xuebin Wang, Chunjun Tian. Synthesis and biodistribution of 99mTcN(PDTC)2 as a potential brain imaging agents. Journal of Radioanalytical and Nuclear Chemistry, 2004, 262:505-507
  18. Junbo Zhang*, Xuebin Wang, Jing Liu. Synthesis and biodistribution in mice of a new 99mTc nitrido complex for brain imaging. Journal of Labelled Compounds and Radiopharmaceuticals, 2004, 47: 647-655
  19. Junbo Zhang, Xuebin Wang, Chunyun Li. Synthesis and biodistribution of a new 99mTc nitrido complex for cerebral imaging. Nuclear Medicine and Biology, 2002, 29(6), 665-669
  20. Junbo Zhang*, Xuebin Wang, Chunyun Li. Synthesis and biodistribution of 99mTcN(CHIPDTC)2 as a potential myocardial perfusion imaging agent. Journal of Radioanalytical and Nuclear Chemistry, 2002, 254(1), 99-101