基本情况

梁淑芳，博士，四川大学生物治疗国家重点实验室教授、博士生导师。2003年毕业于四川大学华西基础医学院获生物化学与分子生物学博士学位。2003年8月到2005年8月在复旦大学蛋白质组研究中心/化学系从事蛋白质组学与化学生物学的博士后研究工作。2005年9月到2010年6月任四川大学生物治疗国家重点实验室/重大疾病“985”平台，副教授，硕士生导师。


研究领域

现主要从事蛋白质组学、基因功能研究及肿瘤的发病机理与生物技术药物研发等研究


科研项目

已主持国家自然基金3项、四川省杰出青年基金项目及应用基础研究项目，主持完成横向项目3项，获得教育部“新世纪优秀人才支持计划”资助，主研国家973项目及863及重大专项等多个项目


论文发表

  1. Zhizhong Xu, Guobo Shen, Xiangying Xia, Xinyu Zhao, Peng Zhang, Huanhuan Wu, Qingfa Guo, Zhiyong Qian, Yuquan Wei, Shufang Liang*. Comparisons of three polyethyleneimine-derived nanoparticles as a gene therapy delivery system for renal cell carcinoma. J. Translational Medicine, 2011, 9: 46 (*通讯作者)
  2. Shufang Liang*, Zhizhong Xu, Xuejiao Xu, Xia Zhao, Canhua Huang, Yuquan Wei.Quantitative proteomics for cancer biomarker discovery. Combinatorial Chemistry&High Throughput Screening, 2011
  3. Shufang Liang, Afu Fu, Qiang Zhang, et al. Honokiol inhibits cell migration via IQGAP1 downregulation discovered by a quantitative pharmaceutical proteomic analysis. Proteomics, 2010, 10: 1474-1483
  4. Guobo Shen, Shufang Liang*, Zhizhong Xu, et al. Downregulated expression of HSP27 in human glioma tissues discovered by a quantitative proteomic analysis. Proteome Science, 2010, 8: 17
  5. Shufang Liang*, Yuhuan Xu, Guobo Shen, et al. Quantitative protein expression profiling of 14-3-3 isoforms in human renal carcinoma shows 14-3-3 epsilon is involved in limitedly increasing renalcell proliferation. Electrophoresis, 2009, 30(22): 4152-4162
  6. Shufang Liang, Yanbao Yu, Pengyuan Yang, et al. Analysis of the protein complex associated with 14-3-3 epsilon by a deuterated-leucine labeling quantitative proteomics strategy. J.Chromatography B, 2009, 877(7): 627-634
  7. Shufang Liang*, Fengming Gong, Xinyu Zhao, et al. Prokaryotic expression, purification of a new tumor-relative protein FAM92A1-289 and its characterization in renal cell carcinoma. Cancer Lett., 2009, 276:81-87
  8. Shufang Liang*, Guobo Shen, Qingping Liu, et al. Isoform-specific expression and characterization of 14-3-3 proteins in human glioma tissues discovered by stable isotope labeling with amino acids in cell culture-based proteomic analysis. Proteomics-Clin. Appl., 2009, 3: 743-753
  9. Shufang Liang*, Yuhuan Xu, Guobo Shen, et al. Gene expression and methylation status of 14-3-3σ in human renal carcinoma tissues.IUBMB Life, 2008, 60(8): 534-540
  10. Ling B+, Liang S. F.+*, Xu Y. H, et al. Differential proteomic profiles of HeLa cells treated with honokiol using a quantitative proteomic strategy. Amino Acids, 2008,35(1): 115-122 (+共同第一作者)