基本情况

杨铭教授，北京大学医学部天然药物及仿生药物国家重点实验室教授、博士生导师，国务院政府特殊津贴获得者。1986年至1989年，美国乔治亚州立大学化学系，访问学者；1989年至1994年，北京医科大学天然药物及仿生药物国家重点实验室，副研究员；1993年1至6月，新加坡国立大学分子与细胞生物学研究所，客座教授。1994年至今，北京大学医学部天然药物及仿生药物国家重点实验室研究员，教授、博士生导师。

研究领域

一直从事以分子识别为基础的药物设计及药物小分子与作用靶的分子识别研究

论文发表

1. Wang Min, Tu Pengfei, Xu Zhidong, Yu Xiaolin, Yang Ming*. Design and synthesis of guanidinoglycosides directed against the TAR RNA of HIV-1. Helvetica Chimica Acta. 2003, 86:2637-2644
2. Zhi-Dong Xu, Min Wang, Su-Long Xiao, Chun-Li Liu and Ming Yang*. Synthesis, biological evaluation and DNA binding properties of novel bleomycin analogues. Bioorganic & Medicinal Chemistry Letter. 2003, 13: 2595-2599
3. HAO Mei-Rong, YANG Ming* and BU xian-He, Molecular Mechanism of Macrocyclic Polyamines with anti-HIV-1 Activity to Recognize RNA and the Effect on Apoptisis, Prog. Biochem. Biophys., 2002, 29(2):211-215
4. Zhi-Dong Xu, He Liu, Su-Long Xiao, Ming Yang*, Xian-He Bu, Synthesis, crystal structure, antitumor activity and DNA-binding study on the Mn(II) complex of 2H-5-hydroxy-1,2,5-oxadiazo [3,4-f]1,10-phenanthroline, Journal of Inorganic Biochemistry, 2002, 90: 79-84
5. Zhi-Dong Xu, He Liu, Su-Long Xiao, Ming Yang*, Xian-He Bu, Manganese(II) complex of 6,7 dicycandipyridoquinoxaline with antitumor activities: Synthesis, crystal structure and binding with DNA, Journal of Inorganic Biochemistry, 2002, 92:149-155
6. Ming Yang, Shu-mei Zhu et al., Chiral specificity of novel platinum complexes in their cross-membrane transport and DNA molecular recognition, S. Afr. J. Chem., 1997, 50(4):227-232
7. Sulong Xiao. Ming Yang* et al., Synthesis and biological evaluation of DNA Targeting flexible side chain substituted β-Carboline derivatives, Bioorganic & Medicinal Chemistry Letters., 2001, 11:437-441
8. Harry P. Hopkins, JR, Yang Ming*, W. David Wilson and David W. Boykin, Intercalation binding of 6-Substituted Naphtho-thiopheneamides to DNA: Enthalpy and Entropy Components, Biopolymers, 1991, 31:1105-1114
9. He Liu, Miao Du, Xiao-Jing Ge, Xian-He Bu and Ming Yang*. A noverl heptacoordinated cobalt(II) complex of 6,7 dicyanodipyridoquinoxaline (dcdpq):[Co(NO3)2(CH3CN)(dcdpq)], Acta Cryst., 2001,E57, m100-m102
10. Panagiotis C. Zachariadis, Sotiris K. Hasjikakou, Nick Hadjiliadis, Yang Ming*, Yu Xiaolin. Synthesis, study and structural characterization of a new water soluble hexanuclear silver (I) cluster with the 2-mercapto-nicotinic acid with possible antiviral activity, Inorganica Chimica Acta, 2002, 1-5