基本情况

鲍永利,东北师范大学药物基因和蛋白筛选国家工程实验室教授、博士生导师。

 

研究领域

肿瘤发病机制研究、肿瘤诊断试剂研发、抗肿瘤基因工程药物研发、抗肿瘤中药新药筛选

 

教育背景

199810月至20026月 博士,吉林大学免疫教研室

19919月至19947月  硕士,白求恩医科大学免疫教研室

19869月至19917月  学士,白求恩医科大学

 

工作经历

200812月至今 教授,东北师范大学药物基因和蛋白筛选国家工程实验室

200811     副教授,东北师范大学药物基因和蛋白筛选国家工程实验室

200710     副教授,东北师范大学遗传与细胞研究所

20003      讲师,白求恩医科大学免疫教研室

 

论文发表

  1. Zhenbo Song, Yongli Bao*, Yu Zhang, Xuguang Mi, Ping Wu, Yin Wu, ChunLei Yu, Ying Sun, LiHua Zheng, YanXin Huang, Biao Liu and YuXin Li*.Testes-specific protease 50 (TSP50) promotes cell proliferation through the activation of the NF-kappa beta (NF-κB) signaling pathway. Biochem J. 2011, 436(2):457-67
  2. Sun BT, Zheng LH*, Bao YL*, Yu CL, Wu Y, Meng XY, Li YX. Reversal effect of Dioscin on multidrug resistance in human hepatoma HepG2/adriamycin cells. Eur J Pharmacol. 2011, 654(2):129-34
  3. Shi Y, Bao YL*, Wu Y*, Yu CL, Huang YX, Sun Y, Zheng LH, Li YX. Alantolactone Inhibits Cell Proliferation by Interrupting the Interaction between Cripto-1 and Activin Receptor Type II A in Activin Signaling Pathway. J Biomol Screen. 2011 Mar 4. [Epub ahead of print]
  4. Zhang Y, Bao YL*, Yang MT, Wu Y, Yu CL, Huang YX, Sun Y, Zheng LH and Li YX*. Activin A induces SLC5A8 expression through Smad3 and p38 MAPK signaling pathway in human colorectal cancer cell line. Int J Biochem Cell Biol. 2010, 42:19641972
  5. Zhou L, Bao YL*, Zhang Y, Wu Y, Yu CL, Huang YX, Sun Y, Zheng LH and LiYX*. Knockdown of TSP50 inhibits cell proliferation and induces apoptosis in P19 cells. IUBMB Life. 2010, 62(11):825-32
  6. Wang M, Bao YL*, Wu Y, Yu CL, Meng XY, Huang YX, Sun Y, Zheng LH and Li YX*. Basic FGF Downregulates TSP50 Expression via the ERK/Sp1 Pathway. J Cell Biochem. 2010, 111:75-81
  7. Zhang Y, Zhou L, Bao YL*, Wu Y, Yu CL, Huang YX, Sun Y, Zheng LH, Li X*.Butyrate induces cell apoptosis through activation of JNK MAP kinase pathway in human colon cancer RKO cells. Chem Biol Interact. 2010,185: 174181
  8. Zhang Y, Bao Y L*, Wu Y, Yu CL, Sun Y, Li YX*. Identification and characterization of the human SLC5A8 gene promoter.Cancer Genet Cytogenet. 2010,196(2):124-32
  9. Li Z D,Wu Y, Bao Y L*, et al.Identification and characterization of human ARIP2 and its relation to breast cancer. Cytokine. 2009,46: 251-259
  10. Huang Y X, Bao Y L*, et al. Pep-3D-Search: a method for B-cell epitope prediction based on mimotope Analysis. BMC Bioinformatics. 2008, 9:538
  11. Zheng L H, Bao Y L*. Cantharidin reverses multidrug resistance of human hepatoma HepG2/ADM cells via down-regulation of P-glycoprotein expression. Cancer Lett. 2008,272(1):102-109