基本情况

符立梧,中山大学肿瘤防治中心教授,博士生导师。

 

研究领域

抗癌药物药理学、毒理学、抗癌药物分子机理及实现肿瘤化疗个体化的研究、肿瘤干细胞抗药性的研究

 

教育背景

19939月至19967 博士,中山医科大学

19909月至19937 硕士,中山医科大学  

19829月至19877 学士,广东医药学院

 

工作经历

20026月至今 教授,中山大学肿瘤防治中心 

20025月     副研究员,中山大学(原中山医科大学)肿瘤中心 

199811月    讲师,中山医科大学

19909月     助教,广东医药学院  

 

论文发表

  1. Shi Z, Tiwari AK, Patel AS, Fu LW*, Chen ZS.  Roles of sildenafil in enhancing drug sensitivity in cancer.  Cancer Res. 2011 Jun 1;71(11):3735-8. (8.2)
  2. Zhang JY, Mi YJ, Chen SP, Liang YJ, Zheng LS, Shi CJ, Tao LY, Chen LM, Chen HB, Fu LW*.  Euphorbia factor L1 reverses ABCB1-mediated multidrug resistance involving interaction with ABCB1 independent of ABCB1 downregualtion.  J Cell Biochem. 2011;112(4):1076-83. (3.12)
  3. Shi CJ, Wang F, Ren MF, Mi YJ, Yan YY, To KK, Dai CL, Wang YS, Chen LM, Tong XZ, Liang YJ, Fu LW*. Up-regulation of ABCB1/P-glycoprotein by escaping promoter hypermethylation indicates poor prognosis in hematologic malignancy patients with and without bone marrow transplantation. Leuk Res. 2011 Jan;35(1):73-9. (2.9)
  4. Xiang QF, Wang F, Su XD, Liang YJ, Zheng LS, Mi YJ, Chen WQ, Fu LW*. Effect of BIBF 1120 on reversal of ABCB1-mediated multidrug resistance. Cell Oncol (Dordr). 2011 Feb;34(1):33-44. (4.3)
  5. Shi Z, Tiwari AK, Shukla S, Robey RW, Singh S, Kim IW, Bates SE, Peng XX, Abraham I, Ambudkar SV, Talele TT, Fu LW*, Chen ZS*. Sildenafil reverses ABCB1- and ABCG2-mediated chemotherapeutic drug resistance. Cancer Res. 2011 Apr 15;71(8):3029-41.  (7.6)
  6. Wang F, Liang YJ, Wu XP, Chen LM, To KK, Dai CL, Yan YY, Wang YS, Tong XZ, Fu LW*, Prognostic value of the multidrug resistance transporter ABCG2 gene polymorphisms in Chinese patients with de novo acute leukaemia. Eur J Cancer. 2011 Apr 28. [Epub ahead of print] 4.9
  7. Zhang JY, Liang YJ, Chen HB, Zheng LS, Mi YJ, Wang F, Zhao XQ, Wang XK, Zhang H, Fu LW*. Structure Identification of Euphorbia Factor L3 and Its Induction of Apoptosis through the Mitochondrial Pathway. Molecules. 2011;16(4):3222-31. (2.0)
  8. Jin C, Liang YJ, He H, Fu L*.Synthesis and antitumor activity of ureas containing pyrimidinyl group. Eur J Med Chem. 2011 Jan;46(1):429-32.IF3.3
  9. Peng H, Liang Y, Chen L, Fu L*, Wang H, He H*. Efficient synthesis and biological evaluation of 1,3-benzenedicarbonyl dithioureas. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1102-4
  10. Yan YY, Zheng LS, Zhang X, Chen LK, Singh S, Wang F, Zhang JY, Liang YJ, Dai CL, Gu LQ, Zeng MS, T Talele T, Chen ZS, Fu LW*.  Blockade of Her2/neu binding to Hsp90 by emodin azide methyl anthraquinone derivative induces proteasomal degradation of Her2/neu. Mol Pharm. 2011 Aug 3. [Epub ahead of print] 5.4