基本情况
符立梧,中山大学肿瘤防治中心教授,博士生导师。
研究领域
抗癌药物药理学、毒理学、抗癌药物分子机理及实现肿瘤化疗个体化的研究、肿瘤干细胞抗药性的研究
教育背景
1993年9月至1996年7月 博士,中山医科大学
1990年9月至1993年7月 硕士,中山医科大学
1982年9月至1987年7月 学士,广东医药学院
工作经历
2002年6月至今 教授,中山大学肿瘤防治中心
2002年5月 副研究员,中山大学(原中山医科大学)肿瘤中心
1998年11月 讲师,中山医科大学
1990年9月 助教,广东医药学院
论文发表
-
Shi Z, Tiwari AK,
Patel AS, Fu LW*, Chen ZS. Roles of sildenafil in enhancing drug
sensitivity in cancer. Cancer Res. 2011 Jun 1;71(11):3735-8. (8.2)
-
Zhang
JY, Mi YJ, Chen SP, Liang YJ, Zheng LS, Shi CJ, Tao LY, Chen LM, Chen HB, Fu
LW*. Euphorbia factor L1 reverses ABCB1-mediated multidrug
resistance involving interaction with ABCB1 independent of ABCB1
downregualtion. J Cell Biochem. 2011;112(4):1076-83. (3.12)
-
Shi CJ,
Wang F, Ren MF, Mi YJ, Yan YY, To KK, Dai CL, Wang YS, Chen LM, Tong XZ, Liang
YJ, Fu LW*. Up-regulation of ABCB1/P-glycoprotein by escaping promoter
hypermethylation indicates poor prognosis in hematologic malignancy patients
with and without bone marrow transplantation. Leuk Res. 2011 Jan;35(1):73-9.
(2.9)
-
Xiang
QF, Wang F, Su XD, Liang YJ, Zheng LS, Mi YJ, Chen WQ, Fu LW*. Effect of BIBF
1120 on reversal of ABCB1-mediated multidrug resistance. Cell Oncol (Dordr).
2011 Feb;34(1):33-44. (4.3)
-
Shi Z,
Tiwari AK, Shukla S, Robey RW, Singh S, Kim IW, Bates SE, Peng XX, Abraham I,
Ambudkar SV, Talele TT, Fu LW*, Chen ZS*. Sildenafil reverses ABCB1- and
ABCG2-mediated chemotherapeutic drug resistance. Cancer Res. 2011 Apr
15;71(8):3029-41. (7.6)
-
Wang F,
Liang YJ, Wu XP, Chen LM, To KK, Dai CL, Yan YY, Wang YS, Tong XZ, Fu LW*, Prognostic
value of the multidrug resistance transporter ABCG2 gene polymorphisms in
Chinese patients with de novo acute leukaemia. Eur J Cancer. 2011 Apr 28. [Epub
ahead of print] (4.9)
-
Zhang
JY, Liang YJ, Chen HB, Zheng LS, Mi YJ, Wang F, Zhao XQ, Wang XK, Zhang H, Fu
LW*. Structure Identification of Euphorbia Factor L3 and Its Induction of
Apoptosis through the Mitochondrial Pathway. Molecules. 2011;16(4):3222-31.
(2.0)
-
Jin C, Liang
YJ, He H, Fu L*.Synthesis and antitumor activity of ureas containing
pyrimidinyl group. Eur J Med Chem. 2011 Jan;46(1):429-32.(IF:3.3)
-
Peng H,
Liang Y, Chen L, Fu L*, Wang H, He H*. Efficient synthesis and biological
evaluation of 1,3-benzenedicarbonyl dithioureas. Bioorg Med Chem Lett. 2011 Feb
15;21(4):1102-4
-
Yan YY,
Zheng LS, Zhang X, Chen LK, Singh S, Wang F, Zhang JY, Liang YJ, Dai CL, Gu LQ,
Zeng MS, T Talele T, Chen ZS, Fu LW*. Blockade of Her2/neu binding
to Hsp90 by emodin azide methyl anthraquinone derivative induces proteasomal
degradation of Her2/neu. Mol Pharm. 2011 Aug 3. [Epub ahead of print] (5.4)