基本情况
陆军，东北师范大学生命科学学院遗传与细胞研究所教授、博士生导师。
研究领域
肿瘤相关基因沉默和活化的表观遗传调控、肿瘤细胞转移和衰老的表观遗传学机制和表观修饰酶抑制剂的筛选及抗肿瘤活性的研究
教育背景
1998年 博士，东北师范大学遗传与细胞研究所
1995年 硕士，吉林大学酶工程国家重点实验室
1988年 学士，山东大学
论文发表
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Yu
Zhang, Yanyan Gao, Guoping Zhang, Shuyan Huang, Zhixiong Dong, Chenfei Kong,
Dongmei Su, Juan Du, Shan Zhu, Qian Liang, Jianchao Zhang, Jun Lu* and Baiqu
Huang, DNMT3a plays a role in switches between doxorubicin-induced
senescence and apoptosis of colorectal cancer cells. International Journal of
Cancer, 2011, 128:551-561
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Zhixiong
Dong, Ruikang Tan, Jian Cao, Yang Yang, Chenfei Kong, Juan Du, Shan Zhu, Yu
Zhang, Jun Lu, Baiqu Huang*, Shuxia Liu*, Discovery of polyoxometalate-based
HDAC inhibitors with profound anticancer activity in vitro and in vivo.
European Journal of Medicinal Chemistry, 2011, 46(6):2477-2484
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Chenfei
Kong, Changqing Wang, Liping Wang, Musong Ma, Chunbo Niu, Xiaoqian Sun, Juan
Du, Zhixiong Dong, Shan Zhu, Jun Lu*, Baiqu Huang*, NEDD9 is a positive
regulator of epithelial-mesenchymal transition and promotes invasion in
aggressive breast cancer. PLoS ONE, 2011, 6(7): e22666
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Juan Du,
Lin Li, Zhouluo Ou, Chenfei Kong, Yu Zhang, Zhixiong Dong, Shan Zhu, Hao Jiang,
Zhimin Shao, Baiqu Huang*, Jun Lu*, FOXC1, a target of polycomb, inhibits
metastasis of breast cancer cells. Breast Cancer Research and Treatment, 2011
Apr 5. [Epub ahead of print]
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Dongmei
Su, Xiue Peng, Shan Zhu, Ying Huang, Zhixiong Dong, Yu Zhang, Jianchao Zhang,
Qian Liang, Jun Lu*, Baiqu Huang*, Role of p38 MAPK pathway in BMP4-mediated
Smad-dependent premature senescence in lung caner cells. Biochemical Journal,
2010, 433(2):333-343
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Dongmei
Su, Shan Zhu, Xuefang Han, Yunpeng Feng, Hui Huang, Guoling Ren, Lina Pan, Yu
Zhang, Jun Lu*, Baiqu Huang*, BMP4-Smad signal pathway mediates
Adriamycin-induced premature senescence in lung cancer cells. Journal of
Biological Chemistry, 2009, 284(18): 12153-12164
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Guoling
Ren, Guocui Zhang, Zhixiong Dong, Zhiwei Liu, Lin Li, Yunpeng Feng, Dongmei Su,
Yu Zhang, Baiqu Huang, Jun Lu*, Recruitment of HDAC4 by transcription factor
YY1 represses HOXB13 to affect cell growth in AR-negative prostate cancers. The
International Journal of Biochemistry & Cell Biology, 2009, 41(5):1094-1101
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Yu
Zhang, Shuyan Huang, Wei Dong, Lin Li, Yunpeng Feng, Lina Pan, Zhenkun Han,
Xiuli Wang, Guoling Ren, DongmeiI Su, Baiqu Huang, Jun Lu*, SOX7 is
down-regulated in colorectal cancer, induces apoptosis and inhibits
proliferation of colorectal cancer cells. Cancer Letters, 2009, 277(1):29-37
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Xiuli Wang,
Lina Pan, Yunpeng Feng, Yanle Wang, Qiuju Han, Liping Han,Songyan Han, Jianhua
Guo, Baiqu Huang, Jun Lu*, p300 plays a role in p16INK4a expression and
cell cycle arrest. Oncogene,2008, 27:1894-1904