Personal Information

Dr. William CS Cho B., Chin. Med., B. Sc. (Hons.), M. Phil., Ph. D. FHKIMLS, Chartered Scientist (UK), FHKSMDS, FIBMS (UK), Consultant of Registered Chinese Medicine Practitioner Association, Registered Chinese Medicine Practitioner (HK),  Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong.

 

Research Interests

integrative medicine, herbal medicine, microRNA, molecular oncology, lymphoma, pathology, clinical cancer research, pharmacology, molecular diagnostics, tumor marker discovery, cancer therapeutics, proteomics, bioinformatics, diabetes mellitus, and drug target discovery

 

Publications

  1. Özdemir V, Cho WC. Theranostics: rethinking postgenomic diagnostics. Expert Rev MolDiagn. 2012; 12 (8)
  2. Cho WC, Ling C-Q. Natural products for liver diseases: basic, clinical, and translationalresearch. Evid Based Complement Alternat Med. 2012
  3. Jiang W, Peng J, Zhang Y, Cho WC, Jin K. The implications of cancer stem cells for cancer therapy. Int J Mol Sci .2012; 13 (12): 16636-16657
  4. He Y, Zhao X, Cho WC, Gao J, Fan L, Yang G, Chen H. Quantum dots-based immunofluorescent imaging of stromal fibroblasts caveolin-1 and light chain 3B expression and identification of their clinical significance in human gastric cancer. Int J Mol Sci. 2012; 13 (11): 13764-13780
  5. López E, Cho WC. Phosphoproteomics and lung cancer research. Int J Mol Sci 2012; 13 (10): 12287-12314
  6. Li T, Cho WC. MicroRNAs: mechanisms, functions and progress. Genomics Proteomics Bioinformatics. 2012; 10 (5): 237-238
  7. He B, Pan Y, Cho WC, Xu Y, Gu L, Nie Z, Chen L, Song G, Gao T, Li R, Wang S. The association between four genetic variants in microRNAs (rs11614913, rs2910164, rs3746444, rs2292832) and cancer risk: evidence from published studies. PLoS One. 2012; 7 (11): e49032
  8. Jiang B, Mason J, Jewett A, Cho WC, Man Y. Tube-like structures with co-expression ofD2-40 and CD34: newly formed vasculatures? Int J Biol Sci. 2012; 8 (8): 1206-1216
  9. Wu K, House L, Liu W, Cho WC. Personalized targeted therapy for lung cancer. Int J MolSci. 2012; 13 (9): 11471-11496
  10. Cho WC. Personalized medicine through genome science and network biology advances. Gastric Breast Cancer. 2012; 11 (4): 216-220
  11. Chen X, Andersson R, Cho WC, Christiani D, Coico R, Drazen J, Ege M, Fehniger T, Gao H, Jin K, Liebman MN, Lopez E, Marraro G, Marko-Varga G, Marincola FM, Popescu LM, Spada C, Shahzad A, Wang E, Wang W, Wang X, Wang Y-X, Xia J, Qu J. The international effort: building the bridge for translational medicine: report of the 1st International Conference of Translational Medicine (ICTM). Clin Transl Med. 2012; 1: 15
  12. Cho WC. Tumor diversity: implementing NGS into clinic. Gastric Breast Cancer. 2012; 11 (3): 121-126
  13. Cho WC. Science and technology: revealing genome networks for improving health. Gastric Breast Cancer. 2012; 11 (2): 58-64
  14. Cho WC. The up and down of KRAS testing for personalized colorectal cancer treatment. Gastric Breast Cancer. 2012; 11 (1): 29-31
  15. Eddouks M, Chattopadhyay D, De Feo V, Cho WC. Medicinal plants in the prevention and treatment of chronic diseases. Evid Based Complement Alternat Med. 2012; 2012: 458274
  16. Cho WC, Ziogas DE, Katsios C, Roukos DH. Emerging personalized oncology: sequencing and systems strategies. Future Oncol. 2012; 8 (6): 637-641
  17. Qi CF, Kim YS, Xiang S, Abdullaev Z, Torrey TA, Janz S, Kovalchuk AL, Sun J, Chen D, Cho WC, Gu W, Morse HC III. Characterization of ARF-BP1/HUWE1 interactions with CTCF, MYC, ARF and p53 in MYC-driven B cell neoplasms.  Int J Mol Sci. 2012; 13 (5): 6204-6219
  18. Cho WC. MicroRNAs as therapeutic targets and their potential applications in cancer therapy. Expert Opin Ther Targets. 2012; 16 (8): 747-759
  19. Xu DD, Hoeven R, Rong R, Cho WC. Rhynchophylline protects cultured rat neurons against methamphetamine cytotoxicity. Evid Based Complement Alternat Med. 2012; 2012: 636091
  20. Cho WC. Great potential of microRNAs as predictive and prognostic markers for cancer. Expert Rev Mol Diagn. 2012; 12 (4): 315-318
  21. Zhong LL, Chen HY, Cho WC, Meng XM, Tong Y. The efficacy of Chinese herbal medicine as an adjunctive therapy for colorectal cancer: a systematic review and meta-analysis. Compliment Ther Med. 2012; 20 (4): 240-252
  22. Liu N, Chen NY, Cui RX, Li WF, Li Y, Wei RR, Zhang MY, Sun Y, Huang BJ, Chen M,He QM, Jiang N, Chen L, Cho WC, Yun JP, Zeng J, Liu LZ, Li L, Guo Y, Wang HY, Ma J. Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis. Lancet Oncol. 2012; 13 (6): 633-641
  23. Chan LW, Wang FF, Cho WC. Genomic sequence analysis of EGFR regulation by microRNAs in lung cancer. Curr Top Med Chem. 2012; 12 (8): 920-926
  24. Cho WC. Exploiting the therapeutic potential of microRNAs in human cancer. Expert Opin Ther Targets. 2012; 16 (4): 345-350
  25. Cho WC. Circulating microRNAs as minimally invasive biomarkers for cancer theragnosis and prognosis. Front Genet. 2011;2:7
  26. Cho WC. Grand challenges and opportunities in deciphering the role of non-coding RNAs in human diseases. Front Genet. 2011; 2: 1
  27. Cho WC. Targeting the signaling pathways in cancer therapy. Expert Opin Ther Targets. 2012; 16 (1): 1-3
  28. Cho WC. Proteome profiling for the identification of lung cancer signatures. Expert Rev Proteomics. 2011; 8 (6): 689-692
  29. Cho WC. Promises and challenges in developing miRNA as a molecular diagnostic tool for lung cancer. Expert Rev Mol Diagn. 2011; 11 (8): 763-766
  30. Cho WC. Epigenetic alteration of microRNAs in feces of colorectal cancer and its clinical significance. Expert Rev Mol Diagn. 2011; 11 (7): 691-694


Book chapters

  1. Cho WC. The scientific evidence of using Astragalus membranaceus in cancer therapy. In: Lien EL, Adams JD (Eds). Traditional Chinese medicine: Scientific basis for its use. Royal Society of Chemistry, 2012
  2. Cho WC. Omics approaches in cancer research. In: Cho WC (ed). An omics perspective on cancer research. Heidelberg, Germany: Springer 2010: 1-9
  3. Cho WC. Cancer biomarkers (an overview). In: Hayat MA (ed). Methods of cancer diagnosis, therapy and prognosis. Volume 7. Heidelberg, Germany: Springer 2010: 21-40
  4. Cho WC. Most common cancers in Asia-Pacific region: nasopharyngeal carcinoma. In: Cancer report of Asian-Pacific region 2010. Asian Pacific Organization for Cancer Prevention 2010: 284-289
  5. Cho WC. Proteinchip. In: Schwab M (Ed). Encyclopedia of cancer. Volume 3. 2nd edition. Heidelberg, Germany: Springer 2009: 2475-2478
  6. Cho WC. Chinese versus Western medicine. In: Schwab M (ed). Encyclopedia of cancer, Volume 3. 2nd edition. Heidelberg, Germany: Springer 2009: 652-654
  7. Cho WC. Astragalus, Astragalus membranaceus (Fisch) Bge. In: Recent progress in medicinal plant, Volume 28. Ethnomedicine: Source and Mechanism II 2009: 31-45
  8. Cho WC. Ginseng, Panax ginseng CA Meyer. In: Recent progress in medicinal plant, Volume 28. Ethnomedicine: Source and Mechanism II 2009: 19-30
  9. Yip TT, Cho WC, Cheng WW, Chan JW, Ma VW, Yip TT, et al. Application of proteinchip array profiling in serum biomarker discovery for patients suffering from severe acute respiratory syndrome. In: Rampal JB (ed). Methods in molecular biology, Volume 382. Microarrays, Volume 2. 2nd edition. Totowa, NJ: Humana Press Inc 2007: 313-331