动脉血气分析在新生儿窒息中的临床研究

Clinical Research of Arterial Blood Gas Analysis for Neonatal Asphyxia

摘要: 目的：探讨动脉血气分析在新生儿窒息中诊断中的临床价值。方法：选取2013年10月到2014年4月在我院产科出生的1分钟Apgar ≤ 7分的40例新生儿为窒息组，其中3 < Apgar评分 ≤ 7分者为轻度窒息组，≤3者为重度窒息组，同期选择Apgar评分 ≥ 8分者50例生后无窒息、病情相对稳定的新生儿为对照组，分别于生后1小时内行血气分析，并将与Apgar评分进行相关性分析。结果：窒息组与对照组相比，其PH、PO₂、BE、HCO₃、乳酸值降低，PCO₂则升高，P < 0.05差异有统计学意义，而重度窒息组比轻度窒息组降低(或升高)更明显。结论：动脉血气分析联合Apgar评分有助于新生儿窒息的诊断及客观的反应新生儿缺氧缺血的性质及严重程度，并有利于预测新生儿预后。

Abstract: Objective: To explore the clinical value of arterial blood gas analysis in the diagnosis of neonatal asphyxia. Method: Choose 40 infants born from October, 2013 to April, 2014 in our hospital with 1 min Apgar score ≤ 7 as asphyxia group, within which 3 < 1 min Apgar score ≤ 7 as mild asphyxia group, Apgar ≤ 3 as severe asphyxia group; at the same time, choose 50 infants with 1 min Apgar score ≥ 8 points, and without symptoms of asphyxia, relatively stable as contrast group. One hour after the infants born, we carry out an analysis of blood gas, and make a relevant analysis with Apgar evaluation. Results: The result comes out that compared with the contrast group, infants in asphyxia group have decreased value in PH, PO₂, BE,HCO₃ and Lactic acid, and have increased value in PCO₂. While, severe asphyxia group has more obvious changes in values. Conclusion: Ar-terial blood gas analysis, together with Apgar evaluation can help to diagnose neonatal asphyxia. What’s more, they can reflect the quality and severity of HIE more objectively, and help to predict the prognosis of neonatal.