肾上腺髓质增生症病例报告一例
One Case of Adrenal Medullary Hyperplasia
DOI: 10.12677/ACRPO.2014.31003, PDF, HTML, 下载: 2,771  浏览: 9,081 
作者: 洪艳艳:安徽医科大学第二附属医院肿瘤科,合肥;黄 祥:中国科学院合肥物质科学研究院肿瘤医院肿瘤科,合肥
关键词: 甲状腺肿瘤PET/CT肾上腺增生诊断Thyroid Neoplasms; Positron-Emission Tomography and Computed Tomography; Adrenal HyperplasiaDiagnosis
摘要: 患者,男,51岁,曾行2次甲状腺手术。1992年术后病理不详。2007(2次手术)术后病理证实为甲状腺髓样癌。术后口服甲状腺素片至今。20136月因左腰部间歇性隐痛就诊我科。PET/CT见双侧肾上腺占位,FDG代谢轻度增高。20136月行左侧肾上腺切除术,术中见左侧肾上腺多发结节占位,直径约3 cm。术后病理:左侧肾上腺髓质结节状增生。右侧肾上腺占位暂未给予特殊处理,以随访为主。随访至201310月底,患者一般情况良好,血压稳定,右侧肾上腺占位较前相仿。 A 51-year-old man underwent two thyroid surgeries. The first operation called left thyroidectomy was in 1992 with unclear pathological results. He underwent right thyroidectomy in 2007 and medullary thyroid carcinoma was pathologically confirmed. He has been in oral administration of thyroxine after the first surgery. The patient consulted the doctor in our department because of suffering from the pain in his left hip on June 2013. PET/CT examination revealed bilateral adrenal masses with slightly increased FDG metabolic. And then he underwent a left adrenalectomy. During the operation, the surgeon found multiple nodules occupying the left adrenal gland with a diameter of about 3 cm. Histopathological report: nodular hyperplasia of the left medulla. We follow up the right adrenal mass which was given no special treatment until October 2013. The patient was in good condition whose right adrenal masses were similar as the previous ones.
文章引用:洪艳艳, 黄祥. 肾上腺髓质增生症病例报告一例[J]. 亚洲肿瘤科病例研究, 2014, 3(1): 9-11. http://dx.doi.org/10.12677/ACRPO.2014.31003

参考文献

[1] 孙则禹, 甘卫东 (2003) 肾上腺髓质增生. 中华泌尿外科杂志, 9, 581-582.
[2] Carney, J.A., Sizemore, G.W. and Sheps, S.G. (1976) Adrenal medullary disease in multiple endocrine neoplasia, type 2: pheochromocytoma and its precursors. American Journal of Clinical Pathology, 66, 279-290.
[3] Grogan, R.H., Pacak, K., Pasche, L., et al. (2011) Bilateral adrenal medullary hyperplasia associated with an SDHB mutation. Journal of Clinical Oncology, 29, e200-202.
[4] 吴阶平 (1977) 肾上腺髓质增生问题. 中华医学杂志, 4, 331-333.
[5] 吴阶平, 徐峰极, 曾正培(1985) 肾上腺髓质增生(15例患者的长期随诊). 中华泌尿外科杂志, 1, 1-3.
[6] M. L. Brandi, R. F. Gagel, A. Angeli, et al. (2001) Guidelines for diagnosis and therapy of MEN type 1 and type 2. The Journal of Clinical Endocrinology & Metabolism, 86, 5658-5671.
[7] Okada, M., Shimono, T., Komeya, Y., et al. (2009) Adrenal masses: The value of additional fluorodeoxyglucose-positron emission tomogra-phy/computed tomography (FDG-PET/CT) in differentiating between benign and malignant lesions. Annals of Nuclear Medicine, 23, 349-354.
[8] Yun, M., Kim, W., Alnafisi, N., et al. (2001) 18F-FDG PET in characterizing adrenal lesions detected on CT or MRI. Journal of Nuclear Medicine, 42, 1795-1799.
[9] 罗家伦, 徐慧琴, 何延辉, 等 (2012) PET-CT在肾上腺转移癌诊断中的价值及其诊断标准探讨. 国际放射医学核医学杂志, 2, 87-91.
[10] 张佐良, 丁强, 管一晖, 等 (2004) 18F-FDG PET鉴别肾上腺良恶性肿瘤的临床价值. 临床泌尿外科杂志, 9, 538-540.
[11] 胡岚亭, 郭峰, 王胜军, 倪泽称, 汪清 (2011) PET/CT 在泌尿系肿瘤诊断中的价值. 中华临床医师杂志 (电子版), 7, 22.
[12] 祝捷, 邱建新, 范昱, 等 (2004) 肾上腺转移癌37例临床分析. 临床泌尿外科杂志, 10, 609-611.
[13] 张荣荣, 廖洪, 许国辉, 等 (2008) 肾上腺转移癌28例临床诊治分析. 肿瘤预防与治疗, 4, 403-405.
[14] 杨金校, 孙颖浩, 王林辉, 等 (2004) 肾上腺转移癌(附11例报告). 中华泌尿外科杂志, 5, 5-7.
[15] Kasperlik-Zeluska, A.A., Roslonowska, E., Slowinska-Srzed- nicka, J., et al. (1997) Incidentally discovered adrenal mass (incidentaloma): Investigation and management of 208 patients. Clinical Endocrinology, 46, 29-37.