早产儿的临床特点及营养支持对其生产发育的影响
Clinical Features of Premature and Nutrition Intervention Effect on the Growth and Development of Premature Infants
DOI: 10.12677/HJFNS.2014.32006, PDF, HTML,  被引量 下载: 3,005  浏览: 10,662 
作者: 姜燕飞, 李勇:北京大学医学部公共卫生学院营养与食品卫生学系,北京;北京大学医学部公共卫生学院母婴营养研究中心,北京;戴智勇:北京大学医学部公共卫生学院母婴营养研究中心,北京;澳优乳业(中国)有限公司,长沙
关键词: 早产儿临床特点生长发育营养支持Premature Clinical Characteristics Growth and Development Nutrition Intervention
摘要: 早产儿是指凡胎龄满28周以上,不足37周,出生体重在2500 g以下,身长47 cm以下的活产新生儿。早产儿具有体温调节中枢发育不全、胃动力不成熟、免疫力低下、并发症多等特点,是一个极度未成熟的群体。人类和动物研究均表明,在妊娠晚期和生后早期敏感阶段的营养不良将会对远期的生长发育产生不良影响,表现为大脑重量降低、脑细胞数减少、运动协调能力降低,另外也有足够证据表明,在关键时期的营养不良可造成大脑结构和功能的永久性损害。鉴于早产儿特殊的生理特点,营养支持对早产儿的生长发育起到十分重要的作用。
Abstract: Premature refers to a live birth infant ,whose gestation period is between 28 weeks and 37 weeks; birth weight is less than 2500 g; born height is below 47 cm. Premature infant is an extremely immature group, always accompanying with hypoplasia in temperature-regulating center, immature in stomach function, low immunity and some complications. In reluctant experiments on human and animals, it’s acknowledged that malnutrition occurring at the initial phase and maturation phase will be harmful for further growth and development, characterized by reduction of brain weight or an amount of brain cells, and weak coordination function. By the way, it’s proved by enough evidence that the damage on the brain structure and function caused by malnutrition in critical period is permanent and irreversible. In consideration of the particularity of physiological needs of premature, nutrition intervention will play a very important role in the growth and development of premature infants.
文章引用:姜燕飞, 戴智勇, 李勇. 早产儿的临床特点及营养支持对其生产发育的影响[J]. 食品与营养科学, 2014, 3(2): 29-34. http://dx.doi.org/10.12677/HJFNS.2014.32006

参考文献

[1] 程玉娥, 吴晓英, 陈玉秋 (2004) 早产儿的生理特点及护理. 职业与健康, 2, 154-155.
[2] 邹美姣 (2008) 早产儿的护理. 全科护理, 10, 2768-2769.
[3] 封志纯, 李丽华, 孔祥永, 等 (2011) 晚期早产儿的临床特点及神经发育异常的风险. 临床儿科杂志, 2, 199-200.
[4] 张超 (2004) 小早产儿的管理. 急救医学, 3, 198-200.
[5] 陈超 (2003) 早产儿呼吸暂停的防治. 小儿急救医学, 4, 204-206.
[6] 叶永青, 李岚, 吴巧珍, 等 (2001) 非营养性吸吮对早产儿胃肠道发育影响的临床研究. 实用护理杂志, 17, 32-33.
[7] 蔡勇, 谢宗德 (2003) 改善早产儿消化道动力的途径. 中国当代儿科杂志, 5, 492-493.
[8] Bauer, M.A., Prade, L.S. and Keske-Soares, M. (2008) The oral motor capacity and feeding performance of preterm newborns at the time of transition to oral feeding. Brazilian Journal of Medical and Biological Research, 41, 904-907.
[9] 王晓燕, 孙素静, 解雪梅 (2008) 早产儿56例早期静脉营养观察. 陕西医学杂志, 5, 165.
[10] 鲍春红, 黑静, 黄峰 (2008) 保护早产儿胃肠道黏膜功能的研究进展. 临床和实验医学杂志, 5, 451.
[11] 贺继雯, 张巍 (2009) 早产儿的消化功能及喂养方式. 中国当代医学, 8, 20-21.
[12] 程雁, 王琍琍 (2010) 早产儿喂养不耐受相关因素分析. 中国新生儿科杂志, 4, 236-237.
[13] 周丛乐, 姜毅, 王素寰, 等 (2002) 胎儿期脑损伤的发生与预后研究. 中国当代儿科杂志, 3, 161-163.
[14] 杨锡强, 易著文 (2004) 新生儿颅内出血. In: 儿科学, 第6版, 人民卫生出版社, 北京, 126.
[15] 黎晓新 (2004) 我国早产儿视网膜病变特点的筛查指南. 中华眼底病杂志, 6, 384-386.
[16] Rose, J., Gibbons, K. and Carlson, S.E. (1993) Nutrient needs of the preterm infant. Nutrition in Clinical Practice, 8, 226232.
[17] 张怡娟, 郭卫芳, 于方, 等 (2002) 早产儿免疫相关因素的分析. 河南诊断与治疗杂志, 4, 253-254.
[18] 王丹华 (2009) 科学的营养管理是早产儿健康的基础. 临床儿科杂志, 3, 214-216.
[19] Vlaardingerbroek, H., van Goudoever, J.B. and Van den Akker, C.H. (2009) Initial nutritional management of the preterm infant. Early Human Development, 85, 691-695.
[20] Brahim, H.M., Jeroudi, M.A., Baier, R.J., et al. (2004) Aggressive early total parental nutrition in low-birth-weight infants. Journal of Perinatology, 24, 482.
[21] 姚笠 (2005) 早产儿的合理喂养. 黑龙江医学, 6, 401-402.
[22] 贲晓明 (2009) 早产儿早期营养支持的意义与策略. 实用儿科临床杂志, 14, 1129-1132.
[23] 汤庆娅 (2009) 适合早产儿代谢特征的合理营养管理. 临床儿科杂志, 3, 217-221.
[24] Lucas, A., Bishop, N.J., King, F.J., et al. (1992) Randomised trial of nutrition for preterm infants after discharge. Archives of Disease in Childhood, 67, 324-327.
[25] Bishop, N.J., King, F.J. and Lucas, A. (1993) Increase bone mineral content of preterm infants fed with a nutrient enriched formula after discharge from hospital. Archives of Disease in Childhood, 68, 573-578.
[26] Krauss, A.N., Broen, J., Waldman, S., et al. (1978) Pulmonary function following feeding in low-birth-weight infants. American Journal of Diseases of Children, 132, 139-142.
[27] Nelle, M., Hoecher, C. and Linderkamp, O. (1997) Effects of bolus tube feeding on cerebral blood flow velocity in neonates. Archives of Disease in Childhood-Fetal and Neonatal Edition, 76, 54-56.
[28] 堪华芳 (2008) 早产儿经口喂养与鼻胃管喂养的临床观察. 中国新生儿科杂志, 2, 110-111.
[29] Ehrenkranz, R.A. (2007) Earlier, aggressive nutritional management for very low birth weight infants: Which the evidence? Seminars in Perinatology, 31, 48-55.
[30] 袁惠华, 黎小秀, 张雪宇 (2004) 早产儿胃肠喂养开始时间的临床研究. 中国航天医药杂志, 1, 24-25.
[31] 严超英 (2010) 新生儿重症监护室早产儿营养指南. 实用儿科临床杂志, 14, 1117-1120.
[32] 阳勇, 曹祥, 钱新华, 等 (2010) 早期胃肠内微量喂养对早产儿胃肠外营养相关性胆汁淤积的防治作用. 实用儿科临床杂志, 19, 1474-1476.
[33] 周丛乐, 姜毅, 王素寰, 等 (2002) 胎儿期脑损伤的发生与预后研究. 中国当代儿科杂志, 3, 161-163.
[34] 贺继雯, 张巍 (2009) 早产儿的消化功能及喂养方式. 中国当代医药, 8, 20-21.
[35] 王丹华 (2010) 早产儿喂养的新理念. 中国新生儿科杂志, 5, 257-259.