JPS  >> Vol. 2 No. 3 (August 2014)

    The Study of the 5-Ht, T and Tch in the Highly Aggressive Tendency Group’s Blood

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攻击性总胆固醇5-羟色胺睾酮Aggressive TCH 5-HT T


目的:探讨高攻击性人群的生物学特征,为用生物学指标判别攻击性行为人群提供依据,同时对Buss- Perry攻击性修订问卷提供了生理生化指标的验证。方法:发放倪林英修订的Buss-Perry攻击性问卷1160份,根据问卷攻击性分数的不同,在高攻击人群组中选择16名男性为高攻击倾向组,在低攻击人群组中选拔出12名男性为低攻击倾向组。分别对两组人员取肘静脉血3ml并进行离心,对血清中5羟色胺、睾酮、总胆固醇及心率、血压行进测定。结果:1) 高攻击倾向组血清中5-HT和T浓度明显高于低攻击倾向组(P < 0.01),其中高攻击倾向组5-HT、T的浓度分别是低攻击倾向组的1.31倍和1.51倍。2) 高攻击倾向组血清TCH浓度明显低于低攻击倾向组(P < 0.05),低攻击倾向组TCH的浓度是高攻击倾向组的1.16倍。3) 高攻击倾向组心率和血压低于低攻击倾向组(P > 0.05)。结论:高攻击性男性血清中5-HT、T的浓度明显高于正常男性,血清中的TCH浓度明显低于正常男性。通过倪林英修订的Buss-Perry攻击性问卷所区分的不同攻击性群体在生化指标上有显著性差异。

Objective: To investigate biological characteristics of high aggressive crowd, to provide the basis for the biological index to distinguish the aggressive behavior group, meanwhile to verify the Buss-Perry Aggression Questionnaire in physiological and biochemical index. Methods: issuing 1160 Buss-Perry Aggression Questionnaires revised by Ni Linying. Accronding to the Aggression Questionnaire scores of different subjects, we choose 16 men in the high aggressive population group as high aggressive tendency group, and choose 12 men in the low aggressive population group as low aggressive tendency group. We gather 3 ml of two groups’ blood with centrifugation, and test the TCH、5-HT, T of the serum and heart rate, blood respectively. Results: 1) The 5-HT and T of high aggressive tendency group serum are significantly higher than that of the low aggression tendency group (P < 0.01). The 5-HT and T of high tendency aggressive group serum are respec-tively 1.31 times and 1.51 times to the low aggression tendency group. 2) The TCH of high aggres-sive tendency group serum are significantly lower than that of low aggression tendency group (P < 0.05). The TCH of high tendency aggressive group serum are 1.16 times to the low aggression ten-dency group. 3) The heart rate and blood pressure of high aggressive tendency group are lower than that of the low aggression tendency group (P > 0.05). Conclusion: The 5-HT and T of the high aggressive men serum are higher than those of normal men obviously; the TCH is significantly lower than that in normal men. The different aggressive groups that are distinguished by the Buss-Perry Aggression Questionnaire revised by Ni Linying are significantly different in the biochemical in-dexes. 5-HT, T and TCH can be used as an important index to judge the aggressive of people.

胡柏平, 李树玖. 对高攻击性倾向人群血液中5羟色胺、睾酮及总胆固醇的研究[J]. 生理学研究, 2014, 2(3): 13-18.


[1] 倪林英 (2005) 大学生攻击行为及其影响因素的研究. 硕士论文, 江西师范大学, 南昌.
[2] Raine, A. (1997) Psychophysiology and antisocial behavior: A biosocial perspective and a prefrontal dysfunction hypothesis. In: Stoff, D., Breiling, J. and Maser, J.D., Eds., Handbook of Antisocial Behavior, Wiley, New York, 289- 304.
[3] Raine, A., Venables, P.H., Mednick, S.A. and Pollock, V. (1999) Reduced skin conductance orienting deficits and increased al-coholism in schizotypal criminals. Journal of Abnormal Psychology, 108, 299-306.
[4] Scarpa, A. and Ollendick, T.H. (2003) Community violence exposure in a young adult sample: III. Psychophysiology and victimization interact to affect risk for aggression. Journal of Community Psychology, 31, 321-338.
[5] 王振宏 (2007) 身体攻击行为学生自主神经活动的情绪唤醒特点. 心理学报, 39, 277-284.
[6] Davidson, R.J., Pizzagalli, D., Nitschke, J.B. and Kalin, N.H. (2003) Parsing the subcomponents of emotion and disorder of emotion: Perspectives from affective neuroscience. In: Davidson, K., Scherer, R. and Goldsmith, H.H., Eds., Handbook of Affective Science, Oxford University Press, New York, 8-24.
[7] Muldoon, M.F. and Manuck, B. (1990) Lowering cholesterol concentrations and mortality: A quantitative review of primary prevention trials. British Medical Journal, 301, 309-314.
[8] Jacobs, D., Blackburn, H., Higgins, M., Reed, D., Iso, H., McMillan, G., et al. (1992) Report of the conference of low blood cholesterol: Mortality associations. Circulation, 86, 1046-1060.
[9] Hillbrand, M. and Foster, H.G. (1993) Serum cholesterol levels and severity of aggression. Psychological Reports, 72, 270.
[10] 杨东英 (2006) 首发精神分裂症兴奋攻击行为与血清胆固醇水平研究. 中国健康心理学杂志, 14, 318-319.
[11] Fontenot, M.B., Kaplan, J.R., Shively, C.A., et al. (1996) Cholesterol, serotoninand behavior in young monkeys. Annals of the New York Academy of Sciences, 794, 352-354.
[12] Sunyaev, S., Ramensky, V., Koch, I., Lathe III, W., Kondrashov, A.S. and Bork, P. (2001) Prediction of deleterious human alleles. Human Molecular Genetics, 10, 591-597.
[13] 辛峰 (2009) 攻击性行为应激对快速力量训练大鼠和血液部分生化指标影响的实验研究. 陕西师范大学, 西安.
[14] Huang, Y.Y., Oquendo, M.A., Friedman, J.M.H., Greenhill, L.L., Brodsky, B., Malone, K.M., et al. (2003) Substance abuse disorder and major depression are associated with the human 5-HT1B receptor gene (HTR1B) G861C polymorphism. Neuropsychopharmacology, 28, 163-169.
[15] Sauer, S., Lechner, D., Berlin, K., Lehrach, H., Escary, J.L., Fox, N., et al. (2000) A novel procedure for efficient ge- notyping of single nucleotide polymoroisms. Nucleic Acids Research, 28, e13.
[16] 朱瑞, 周农 (2006) 攻击的神经生物学基础. 安徽医学, 4, 347-349.
[17] Virkunen, M., Rawlings, R., Tokola, R., Poland, R.E., Guidotti, A., Nemeroff, C., et al. (1994) CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. Archives of General Psychiatry, 51, 20-27.
[18] 余毅震, 黄燕 (2007) 青少年攻击行为与内分泌因素关系的研究. 中国妇幼保健, 14, 1909-1911.
[19] Nelson, R.J. (2001) Molecular basis of aggression. Neuros-ciences, 24, 713-719.