维生素D在自闭症中作用的研究进展
Role of Vitamin D in Autism
DOI: 10.12677/IJPN.2014.34004, PDF, HTML, 下载: 3,675  浏览: 14,141 
作者: 贾飞勇, 单 玲, 冯俊燕, 王 冰, 李洪华, 杜 琳*：吉林大学，第一医院小儿神经康复科，长春
关键词: 自闭症；维生素D；免疫调节；氧化应激；基因稳定；Autism； Vitamin D； Immunologic Regulation； Oxidative Stress； Genomic Stability
摘要: 自闭症临床表现为行为障碍，存在着免疫异常、氧化应激改变甚至基因异常。自闭症患儿普遍存在着维生素D缺乏。维生素D除了传统的钙磷代谢调节作用外，尚具有免疫调节、增加谷胱甘肽的合成及基因稳定等功能。我们最新的研究表明维生素D能够改善自闭症患儿的行为，提示维生素D参与了自闭症的致病过程。本文就维生素D在自闭症中的可能作用的研究进展作一综述。
Abstract: Autism is characterized by abnormal immunology, altered oxidative stress and even genetic ab-normality in addition to behavioral problems. Vitamin D deficiency is ubiquity in children with autism. Vitamin D plays a role in regulating immune, up-regulating glutathione, and controlling genome in addition to traditional action on calcium and phosphate regulation. We recently reported that vitamin D supplementation could improve the behavioral manifestations in autistic child, which illustrated that vitamin D was involved in the pathogenesis of autism. Herein we summarize the research progress of the role of vitamin D in autism.
文章引用：贾飞勇, 单玲, 冯俊燕, 王冰, 李洪华, 杜琳. 维生素D在自闭症中作用的研究进展[J]. 国际神经精神科学杂志, 2014, 3(4): 21-27. http://dx.doi.org/10.12677/IJPN.2014.34004

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