ACM  >> Vol. 5 No. 3 (September 2015)


黄德沛,黄韵红:贵州省肿瘤医院,贵州 贵阳

中枢神经系统淋巴瘤临床特征预后治疗大剂量甲氨蝶呤化疗Central Nervous System Lymphoma Clinical Features Prognosis Treatment High-Dose Methotrexate Chemotherapy



Purpose: Study of clinical features and prognosis of 11 CNS (central nervous system) lymphoma cases. Methods: Discuss on the clinical features and prognosis of the CNS lymphoma by analyzing clinical files of the primary CNS lymphoma patients in our hospital from 2007 to 2013 with recent domestic and international studies for reference. Results: 11 patients temporarily show no relapse of CNS lymphoma after radiotherapies, chemotherapies and follow-up clinic visits. 3 patients relapse after radical and chemical therapies but recover well after follow-up visits in hospital. The general OS survival rate of the 11 cases is 50%. Conclusion: It is difficult to diagnose clinically of the primary CNS lymphoma at its early stage. Large dose of using methotrexate is the main treating method after diagnosis of its pathological mechanism. With synchronous radiotherapy and chemotherapy, the living quality and life span of patients would be enhanced accordingly.

黄德沛, 黄韵红. 原发中枢神经系统淋巴瘤[J]. 临床医学进展, 2015, 5(3): 131-135.


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