学术期刊
切换导航
首 页
文 章
期 刊
投 稿
预 印
会 议
书 籍
新 闻
合 作
我 们
按学科分类
Journals by Subject
按期刊分类
Journals by Title
核心OA期刊
Core OA Journal
数学与物理
Math & Physics
化学与材料
Chemistry & Materials
生命科学
Life Sciences
医药卫生
Medicine & Health
信息通讯
Information & Communication
工程技术
Engineering & Technology
地球与环境
Earth & Environment
经济与管理
Economics & Management
人文社科
Humanities & Social Sciences
合作期刊
Cooperation Journals
首页
化学与材料
有机化学研究
Vol. 3 No. 3 (September 2015)
期刊菜单
最新文章
历史文章
检索
领域
编委
投稿须知
文章处理费
最新文章
历史文章
检索
领域
编委
投稿须知
文章处理费
常用催眠药物研究进展
Progress of Commonly Used Hypnotic Drugs
DOI:
10.12677/JOCR.2015.33015
,
PDF
,
HTML
,
XML
,
被引量
下载: 3,182
浏览: 17,703
作者:
高 婷
,
邵开元
:北京神剑天军医学科学院,北京;
刘亚军
,
王 刚
:北京市信息技术研究所,北京;
胡文祥
:北京神剑天军医学科学院,北京;总装备部疾病预防控制中心,北京
关键词:
催眠药
;
苯二氮?类
;
非苯二氮?类
;
双重受体拮抗剂
;
Hypnotics
;
Benzodiazepine
;
Non-Benzodiazepine
;
Dual Receptor Antagonist
摘要:
本文综述了几类常用催眠药有关研究进展,展望了新型催眠药的探索研究,建议了催眠药物的使用指导原则。
Abstract:
The related research progress in several kinds of commonly used hypnotic was reviewed. The two kinds of novel hypnotic and the guidelines using hypnotic drug were suggested.
文章引用:
高婷, 刘亚军, 王刚, 邵开元, 胡文祥. 常用催眠药物研究进展[J]. 有机化学研究, 2015, 3(3): 105-114.
http://dx.doi.org/10.12677/JOCR.2015.33015
参考文献
[
1
]
陈新谦 (1973) 新编药物学. 第十版, 人民卫生出版社, 北京, 242.
[
2
]
周自永 (1987) 新编常用药物手册. 金盾出版社, 北京, 32.
[
3
]
周晓喜 (2011) 治疗失眠的药物及其研究进展. 海峡药学, 23, 88-90.
[
4
]
郭宗儒 (2005) 药物化学. 高等教育出版社, 北京, 115-124.
[
5
]
Kaplan, H.I. and Sadoek, B.J. (1992) Psyehiatriedrug treatment. Williams & Wilkins, Baltimore, 25.
[
6
]
Michael Kaplan, E. and Dupont, R.L. (2005) Benzodiazepines and anxiety disorders: A review for the practicing physician. Current Opinion in Psychiatry, 21, 41-50.
[
7
]
杨庆林 (2013) 精神疾病患者应用苯二氮䓬类药物状况分析. 中国现代药物应用, 7, 106-107.
[
8
]
姚玲, 曹德鹏 (2012) 住院精神病人苯二氮䓬类药物应用分析. 中国民康医学, 24, 2082-2084.
[
9
]
陈新谦, 金有豫, 汤光 (2007) 新编药物学. 第十六版, 人民卫生出版社, 北京, 11.
[
10
]
王泽民 (2003) 失眠症治疗药物现状调查. 现代中西医结合杂志, 8, 1796-1797.
[
11
]
李华芳, 顾牛范 (2000) 新型非苯二氮䓬类镇静催眠药扎来普隆. 中国新药与临床杂志, 6, 495.
[
12
]
Srinivasan, V., Spence, D.W., Pandi-Perumal, S.R., Trakht, I. and Cardinali, D.P. (2008) Jet lag: Therapeutic use of melatonin and possible application of melatonin analogs. Travel Medicine and Infectious Disease, 6, 17-28.
http://dx.doi.org /10.1016/j.tmaid.2007.12.002
[
13
]
周俊翔, 吴逢波, 唐尧 (2012) 雷美替胺治疗成人慢性失眠的系统评价. 中国循证医学杂志, 3, 314-319.
[
14
]
周俊翔, 余文韬, 吴斌, 柳汝明, 唐尧 (2011) 雷美替胺治疗老年人慢性原发性失眠的系统评价. 中国药房, 38, 3593-3596.
[
15
]
Mini, L., Wang-Weigand, S. and Zhang, J. (2008) Ramelteon 8 mg/d versus placebo in patients with chronic insomnia: Post hoc analysis of a 5-week trial using 50% or greater reduction in latency to persistent sleep as a measure of treatment effect. Clinical Therapeutics, 30, 1316-1323.
http://dx.doi.org /10.1016/S0149-2918(08)80056-2
[
16
]
Uchiyama, M., Hamamura, M., Kuwano, T., Nishiyama, H., Nagata, H. and Uchimura, N. (2011) Evaluation of subjective efficacy and safety of ramelteon in Japanese subjects with chronic insomnia. Sleep Medicine, 12, 119-126.
http://dx.doi.org /10.1016/j.sleep.2010.08.010
[
17
]
Gooneratne, N.S., Gehrman, P., Curubhagavatula, I., Al-Shehabi, E., Marie, E. and Schwab, R. (2010) Effectiveness of ramelteon for insomnia symptoms in older adults with obstructive sleep apnea: A randomized placebo-controlled pilot study. Journal of Clinical Sleep Medicine, 6, 572-580.
[
18
]
Quera Salva, M.A., Vanier, B., Laredo, J., Hartley, S., Chapotot, F., Moulin, C., et al. (2007) Major depressive disorder, sleep EEG and agomelatine: An open-label study. International Journal of Neuropsychopharmacology, 10, 691-696.
[
19
]
Quera-Salva, M.A., Lemoine, P. and Guilleminault, C. (2010) Impact of the novel antidepressant agomelatine on disturbed sleep-wake cycles in depressed patients. Human Psychopharmacology, 25, 222-229.
http://dx.doi.org /10.1002/hup.1112
[
20
]
Hale, A., Corral, R.M., Mencacci, C., Ruiz, J.S., Severo, C.A. and Gentil, V. (2010) Superior antidepressant efficacy results of agomelatine versus fluoxetine in severe MDD patients: A randomized, double-blind study. International Clinical Psychopharmacology, 25, 305-314.
[
21
]
Rajaratnam, S.M., Polymeropoulos, M.H., Fisher, D.M., Roth, T., Scott, C., Birznieks, G. and Klerman, E.B. (2009) Melatonin agonist tasimelteon (VEC-162) for transient insomnia after sleep-time shift: Two randomised controlled multicentre trials. The Lancet, 373, 482-491.
http://dx.doi.org /10.1016/S0140-6736(08)61812-7
[
22
]
Owen, R.T. (2009) Selective histamine H1 antagonism: A novel approach to insomnia using low-dose doxepin. Drugs of Today, 45, 261-267.
http://dx.doi.org /10.1358/dot.2009.45.4.1358835
[
23
]
Roth, A.J., McCall, W.V. and Liguori, A. (2011) Cognitive, psychomotor and polysomnographic effects of trazodone in primary insomniacs. Journal of Sleep Research, 20, 552-558.
http://dx.doi.org /10.1111/j.1365-2869.2011.00928.x
[
24
]
Shen, J., Chung, S.A., Kayumov, L., Moller, H., Hossain, N., Wang, X., et al. (2006) Polysomnographic and symptomatological analyses of major depressive disorder patients treated with mirtazapine. Canadian Journal of Psychiatry, 51, 27-34.
[
25
]
Rosenberg, R., Seiden, D.J., Hull, S.G., Erman, M., Schwartz, H., Anderson, C., et al. (2008) APD 125, a selective serotonin 5-HT2A receptor inverse agonist, significantly improves sleep maintenance in primary insomnia. Sleep, 31, 1663-1671.
[
26
]
王桂芝, 胡海涛, 高健, 赵琦, 张特利 (2009) 镇静催眠药物的研究进展. 中外医疗, 19, 101-103.
[
27
]
Shinomiya, K., Fujimura, K., Kim, Y. and Kamei, C. (2012) Effects of valerian extract on the sleep-wake cycle in sleep-disturbed rats. Acta Medica Okayama, 59, 89-92.
[
28
]
张劲鹏, 张恩霞 (2010) 缬草镇静催眠作用的实验研究. 内蒙古中医药, 10, 34.
[
29
]
孙付军, 陈慧慧, 王春芳 (2010) 柏子仁皂苷和柏子仁油改善睡眠作用的研究. 世界中西医结合杂志, 5, 394- 395.
[
30
]
肖韦华, 刘宗林, 李智欣 (2007) 柏子仁中改善睡眠有效成分的研究. 食品科学, 7, 475-479.
[
31
]
徐仲航, 金向群 (2011) 植物油提取新工艺得到的五味子提取物对小鼠睡眠影响的实验研究. 中国实验诊断学, 5, 819-821.
[
32
]
高剑锋, 张洪生 (2010) 五味子对中枢神经系统作用的研究概述. 中国药师, 12, 1813-1816.
[
33
]
徐丽华, 黄芳, 孙萌, 梁春霞, 吴洁, 余伯阳 (2009) 南北五味子镇静催眠活性部位共有成分的分析. 分析化学, 6, 828-834.
[
34
]
江海涛, 任源浩, 虞蔚岩 (2008) 灵芝提取物在睡眠改善中的功能性研究. 时珍国医国药, 9, 2231-2232.
[
35
]
Cui, X.Y., Cui, S.Y., Zhang, J., Wang, Z.J., Yu, B., Sheng, Z.F., Zhang, X.Q. and Zhang, Y.H. (2011) Extract of Ganoderma lucidum prolongs sleep time in rats. Journal of Ethnopharmacology, 139, 796-800.
http://dx.doi.org /10.1016/j.jep.2011.12.020
[
36
]
黄维, 金邦荃, 程光宇, 杨云峰, 冯波, 吴京燕 (2008) 酸枣仁功效成分测定及改善睡眠保健功能的研究. 时珍国医国药, 5, 1173- 1175.
[
37
]
王丽娟, 张明春, 李彬, 代昆 (2010) 酸枣仁半仿生提取物和醇提取物对睡眠的改善作用. 时珍国医国药, 12, 50.
[
38
]
孙立梅, 张雷 (2012) 酸枣仁水提取物的镇静催眠试验研究. 吉林农业科技学院学报, 2, 1-3.
[
39
]
李培育 (2011) 酸枣仁提取物对小鼠镇静催眠作用的研究. 中国民康医学, 21, 2627-2630.
[
40
]
Fang, X.S., Hao, J.F., Zhou, H.Y., Zhu, L.X., Wang, J.H. and Song, F.Q. (2010) Pharmacological studies on the sedative-hypnotic effect of Semen Ziziphi spinosae (Suanzaoren) and Radix et Rhizoma Salviae miltiorrhizae (Danshen) extracts and the synergistic effect of their combinations. Phytomedicine, 17, 75-80.
http://dx.doi.org /10.1016/j.phymed.2009.07.004
[
41
]
刘正, 郭凌鸿, 徐昕红, 曲卫敏, 黄志力 (2011) 西红花有效成分的神经药理学研究进展. 时珍国医国药, 5, 1202-1204.
[
42
]
张雄飞, 竹剑平 (2008) 白芍提取物对小鼠改善睡眠的影响. 当代医学, 12, 33-34.
[
43
]
李文艳, 黄山君, 王瑞 (2012) 中药白芍的药理作用和质量控制研究进展. 药学服务与研究, 2, 118-122.
[
44
]
贺娟, 冯玛莉, 刘霞, 贾力莉, 武玉鹏, 牛艳艳 (2007) 蛇床子提取物的镇静催眠作用. 山西中医, 5, 61-62.
[
45
]
仝立国, 宋美卿, 冯玛莉, 贾力莉, 武玉鹏, 牛艳艳 (2011) 谱效关系分析蛇床子镇静催眠的活性物质. 山西中医, 6, 52-53.
[
46
]
de Lecea, L., Kilduff, T.S., Peyron, C., Gao, X., Foye, P.E., Danielson, P.E., et al. (1998) The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity. Proceedings of the National Academy of Sciences of the United States of America, 95, 322-327.
http://dx.doi.org /10.1073/pnas.95.1.322
[
47
]
Sakurai, T., Amemiya, A., Lshii, M., Matsuzaki, I., Chemelli, R.M., Tanaka, H., et al. (1998) Orexins and orexin receptors: A family of hypothalamic neuropeptides and G pro-tein-coupled receptor that regulate feeding behavior. Cell, 92, 573-585.
http://dx.doi.org /10.1016/S0092-8674(00)80949-6
[
48
]
Piper, D.C., Upton, N., Smith, M.I. and Hunter, A.J. (2000) The novel brain neuropeptide, orexin-A, modulates the sleep-wake cycle of rats. European Journal of Neuroscience, 12, 726-730.
http://dx.doi.org /10.1046/j.1460-9568.2000.00919.x
[
49
]
Bennett, T., Bray, D. and Neville, M.W. (2014) Suvorexant, a dual orexin receptor antagonist for the management of insomnia. P & T: A Peer-Reviewed Journal for Formulary Management, 39, 264-266.
[
50
]
Herring, W.J., Snyder, E., Budd, K., Hutzelmann, J., Snavely, D., Liu, K., et al. (2012) Orexin receptor antagonism for treatment of insomnia: A randomized clinical trial of suvorexant. Neurology, 79, 2265-2274.
http://dx.doi.org /10.1212/WNL.0b013e31827688ee
[
51
]
Landolt, H.P. and Wehrle, R. (2009) Antagonism of serotonergic 5-HT2A/2C receptors: Mutual improvement of sleep, cognition and mood? European Journal of Neuroscience, 29, 1795-1809.
http://dx.doi.org /10.1111/j.1460-9568.2009.06718.x
[
52
]
Teegarden, B.R., Al Shamma, H. and Xiong, Y. (2008) 5-HT2A inverse-agonists for the treatment of insomnia. Current Topics in Medicinal Chemistry, 8, 969-976.
http://dx.doi.org /10.2174/156802608784936700
[
53
]
Lewis, V. (2009) Undertreatment of menopausal symptoms and novel options for comprehensive management. Current Medical Research Opinion, 25, 2689-2698.
http://dx.doi.org /10.1185/03007990903240519
[
54
]
Griebel, G., Beeské, S., Jacquet, A., Laufrais, C., Alonso, R., Decobert, M., et al. (2013) Further evidence for the sleep-promoting effects of 5-HT2A receptor antagonists and demonstration of synergistic effects with the hypnotic, zolpidem in rats. Neuropharmacology, 70, 19-26.
http://dx.doi.org /10.1016/j.neuropharm.2012.12.008
投稿
为你推荐
友情链接
科研出版社
开放图书馆