中西医药物治疗巩膜炎的研究进展

Review on Treatments of Scleritis with Chinese Medicine and Western Medicine

摘要: 巩膜炎(scleritis)，中医称之为“火疳”，为巩膜组织的炎性反应疾病。因巩膜组织由胶原纤维和少量弹性纤维交错致密排列而成，细胞成分和血管较少，导致该疾病并不常见。然而，由于巩膜代谢缓慢，一旦患病，病程往往迁延难愈。在药物治疗上主要有非甾体抗炎药、甾体抗炎药、皮质类固醇药、免疫抑制剂、生物制剂、中药提取物及中药汤剂。本文归纳了上述药物治疗巩膜炎的给药方式及各自临床疗效，分析其中利弊，为临床医疗工作人员提供医疗证据。

Abstract: Scleritis, also called “episcleritis” in Traditional Chinese Medicine, is an inflammation of sclera tissues. As sclera tissues are compactly composed of collagen fibers and a few of elastic fibers with few cellular constituents and vessels, this disease is uncommon. However, once happened, it has a lingering course due to the slow metabolism of sclera. Drugs mainly include non-steroidal anti-in- flammatory drugs, steroidal anti-inflammatory drugs, corticosteroids, immunosuppressive agent, biological agent, herbal extracts and herbal decoction of Traditional Chinese Medicine. This paper reviewed the administration methods and their clinical effects in treating scleritis with drugs mentioned above, analyzed their advantages and disadvantages, and provided medical evidences for clinical medical staff.