IJPN  >> Vol. 4 No. 3 (August 2015)

    Research Progress of Serotonin in Autism Spectrum Disorders

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王丽丽,杜琳,单玲,冯俊燕,贾飞勇:吉林大学第一医院小儿神经康复科,吉林 长春

孤独症谱系障碍5-HT5-HTTAutism Spectrum Disorder 5-HT 5-HTT



Autism spectrum disorder (ASD) is a group of developmental behavioral disorders which have the main features like different levels of social interaction and communication barriers, restrictive and repetitive behaviors and abnormal interests and activities. The onset of ASD shows a trend of increase year by year, but its etiology is unknown. Serotonin is a monoamine neurotransmitter which is widely present in the human body and has a regulatory role in other neuropsychiatric events. The study found that the 5-HT of patients with ASD level increased in peripheral blood and decreased in the brain. This anomaly was common in ASD patients. 5-HT transporter gene was different from ordinary people. Therefore, the abnormality of 5-HT system may be a risk factor for ASD.

王丽丽, 杜琳, 单玲, 冯俊燕, 贾飞勇. 5-羟色胺在孤独症谱系障碍中的研究进展[J]. 国际神经精神科学杂志, 2015, 4(3): 13-18. http://dx.doi.org/10.12677/IJPN.2015.43003


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