IJPN  >> Vol. 5 No. 1 (February 2016)

    慢性脑供血不足患者的脑血管功能分析
    Analysis of Cerebrovascular Function in Patients with Chronic Cerebral Circulation Insufficiency

  • 全文下载: PDF(392KB) HTML   XML   PP.9-13   DOI: 10.12677/IJPN.2016.51002  
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作者:  

廖远生,杨瑞玲,林菊珊,吴松鹰,吴成翰:福建中医药大学附属第二人民医院神经内科,福建 福州

关键词:
慢性脑供血不足脑血管功能Chronic Cerebral Circulation Insufficiency Cerebrovascular Function

摘要:

目的:研究慢性脑供血不足患者的脑血管功能情况。方法:采用CBA CV300型脑血管功能(CVHI)检测仪分别对120例慢性脑供血不足患者和60例正常对照组进行测定,分析相关指标。结果:慢性脑供血不足(CCCI)患者,随着年龄的增长,平均血流量(Qmean)、最大流速(Vmax)、最小流速(Vmin)、平均流速(Vmean)和差压(DP)等呈显著下降趋势,外周阻力(Rv)、特性阻抗(Zcv)、脉搏波速(Wv)、动态阻力(DR)、临界压(CP)等指标呈现显著升高趋势。CCCI患者的积分值、流速和流量等明显低于对照组,但Rv、Wv及Zcv等明显高于对照组,差异有统计学意义(P < 0.05)。结论:慢性脑供血不足是动脉粥样硬化所致,脑血管功能受损明显,卒中发病风险增加。

Objective: To study the Cerebrovascular Function in patients with chronic cerebral circulation insufficiency (CCCI). Methods: 120 patients diagnosed as CCCI were assigned in test group, and 60 healthy people were in normal control group; they were given CBA CV300 Cerebrovascular hemodynamic indexes (CVHI) examination, and analysis of related indicators. Results: In CCCI, with the age increaing, cerebrovascular hemodynamic synthesized index, including quantity of mean blood flow (Qmean), velocity of maximum blood flow (Vmax), velocity of minimus blood flow (Vmin), velocity of mean blood flow (Vmean), pulse wave velocity (Wv), characteristic impedance (Zcv), resistance of vascular (Rv), development resistance (DR), capillary pressure (CP), pressure difference (DP). The numbers of Qmean, Vmax, Vmin, Vmean and DP appeared to obviously decline, but the numbers of Rv, Zcv, Wv, DR and CP appeared to obviously raise. The CCCI patients’ cerebrovascular hemodynamic synthesized score (CVHS), flow velocity and flow rate are significantly lower than the control group, but the Rv, Wv and Zcv, significantly higher than the control group, the difference was statistically significant. Conclusions: CCCI is the result of atherosclerosis, and Cerebrovascular function was damaged obviously, the risk of stroke is increasing.

文章引用:
廖远生, 杨瑞玲, 林菊珊, 吴松鹰, 吴成翰. 慢性脑供血不足患者的脑血管功能分析[J]. 国际神经精神科学杂志, 2016, 5(1): 9-13. http://dx.doi.org/10.12677/IJPN.2016.51002

参考文献

[1] 彭春平, 吴松鹰. 慢性脑供血不足中西医研究进展[J]. 中西医结合心脑血管病杂志, 2014, 12(11): 1385-1386.
[2] 近藤. 无症状性脑血管病变ヘの对应颈动脉病变の治疗[J]. 日内会杂志, 2000, 86(4): 781.
[3] 祝腊香, 陈观保. 慢性脑供血不足患者的脑血流分析[J]. 实用全科医学, 2007, 5(9): 771-772.
[4] 吕翠, 高波, 姜鸿萍, 等. 慢性脑供血不足患者认知功能障碍与脑血流的相关性分析[J]. 中国实用神经疾病杂志, 2012, 15(3): 1-3.
[5] 黄久仪. 卒中风险评估研究的进展[J]. 中国脑血管病杂志, 2007, 4(12): 566-569.
[6] 王桂清, 钱国正, 杨永举, 等. 脑血管血液动力学指标检测参数的参考值[J]. 中华流行病学杂志, 2003, 24(2): 98-101.
[7] 曹奕丰, 王桂清, 黄久仪, 等. 脑血管血液动力学参数脑卒中预测模型的建立[J]. 中华流行病学杂志, 2003, 24(2): 798-800.
[8] Wu, C.H., Liao, L.M., Yan, X.H., Li, M.D. and Yang, R.M., The Yang Xue Qin Granule Chronic Cerebral Hypoperfusion Study Group (2013) Effects of Yangxue Qingnao Granules on Chronic Cerebral Circulation Insufficiency: A Randomized, Double-Blind, Double-Dummy, Controlled Multicentre Trial. Psychogeriatrics, 13, 29-34.
http://dx.doi.org/10.1111/j.1479-8301.2012.00423.x