有机化学研究  >> Vol. 4 No. 2 (June 2016)

多取代吡喃[2,3-c]吡唑类化合物的在离子液体[Bmim]BF4催化下的四组分一锅法合成
One-Pot Four-Component Synthesis of Multi-Substituted Pyrano[2,3-c] Pyrazole under Ionic Liquid [Bmim]BF4 Catalysis

DOI: 10.12677/JOCR.2016.42007, PDF, HTML, XML, 下载: 1,374  浏览: 3,747  国家科技经费支持

作者: 阿地里江•吾买尔江, 李文博, 夏依努尔•艾力, 梁 杰:新疆大学化学化工学院,新疆 乌鲁木齐

关键词: 多组分反应多取代吡喃[23-c]吡唑类化合物一锅法合成离子液体Multi-Component Reaction Multi-Substituted Pyrano[23-c]pyrazole One-Pot Synthesis Ionic Liquid

摘要: 本文报道了在离子液体[Bmim]BF4催化下以丙酰乙酸甲酯或丙酰乙酸乙酯,苯肼,芳醛和丙二腈等四组分为原料经过一锅法合成了一系列多取代吡喃[2,3-c]吡唑类化合物的方法。该方法具有方便,产率较高等特点,为合成此类化合物提供了一个参考依据。产物的结构通过IR,1H NMR和MS进行表征。
Abstract: A series of multi-substituted pyrano[2,3-c]pyrazole derivatives were synthesized by one-pot reac-tion of ethyl propionyl acetate, phenylhydrazine, aromatic aldehyde and malononitrile. We developed an efficient and convenient method for the synthesis of multi-substituted pyrano[2,3-c]pyrazoles in high yields using ionic liquid [Bmim]BF4 as a catalyst. And structures of the products were characterized by IR, 1H NMR and MS.

文章引用: 阿地里江•吾买尔江, 李文博, 夏依努尔•艾力, 梁杰. 多取代吡喃[2,3-c]吡唑类化合物的在离子液体[Bmim]BF4催化下的四组分一锅法合成[J]. 有机化学研究, 2016, 4(2): 51-55. http://dx.doi.org/10.12677/JOCR.2016.42007

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