以骨髓纤维化为首发外周T细胞淋巴瘤1例并文献复习

1 Cases of Peripheral T Cell Lymphoma Treated with Myelofibrosis and Review of the Literature

摘要: 外周T细胞淋巴瘤(peripheral T-cell lymphoma, PTCL)是一种多样化的淋巴系统恶性增殖性疾病，起源于胸腺后成熟的T淋巴细胞或NK/T细胞，占非霍奇金淋巴瘤的5%~15%，呈现明显的异质性，即临床和病理形态的多样性。骨髓纤维化是一种造血组织中胶原增生，造血功能严重受到影响的一种骨髓增生性疾病。外周T细胞淋巴瘤合并骨髓纤维化少见。

Abstract: Peripheral T cell lymphoma (peripheral T-cell, lymphoma, PTCL) is a diversified lymphatic system malignant proliferative disease, originated from the thymus after mature T cells or NK/T cells, accounting for non Hodgkin's lymphoma from 5% to 15%, showed significant heterogeneity, clinical and pathological morphology of bone marrow fibrosis is diversity. A collagen hyperplasia in hematopoietic tissue, hematopoietic function seriously affected a myeloproliferative disease. Pe-ripheral T cell lymphoma with bone marrow fibrosis is rare.