MS  >> Vol. 7 No. 3 (May 2017)

    Preparation of Three-Dimensional Porous Copper Oxide Nanoflakes and Its Non-Enzymatic Detection of Glucose

  • 全文下载: PDF(1446KB) HTML   XML   PP.309-317   DOI: 10.12677/MS.2017.73042  
  • 下载量: 250  浏览量: 314   国家自然科学基金支持


邵长旭,陈守刚:中国海洋大学材料科学与工程研究院,山东 青岛

多孔氧化铜纳米片无酶传感葡萄糖Porous Copper Oxide Nanoflakes Non-Enzymatic Sensor Glucose



In this paper, three-dimensional porous copper oxide nanoflakes were successfully synthesized on the copper substrate without the use of organic reagents and stabilizers by the combination of liq-uid-solid reaction and high-temperature annealing. The three-dimensional porous structure of copper oxide has a large specific surface area, and the mesopores and micropores on the nanosheets are conducive to the transmission of electron. Using good biocompatibility, conductivity and film of chitosan are used to prepare chitosan copper oxide organic-inorganic composite electrode for nonenzymatic glucose electrochemical sensor. This electrode has the advantages of simple preparation, fast response and low detection line and the sensor is almost insensitive to common interference, such as dopamine, uric acid and ascorbic acid.

邵长旭, 陈守刚. 三维交错多孔氧化铜纳米片的制备及其对葡萄糖的无酶检测[J]. 材料科学, 2017, 7(3): 309-317.


[1] Wild, S., Roglic, G., Green, A., Sicree, R. and King, H. (2004) Global Prevalence of Diabetes: Estimates for the Year 2000 and Projections for 2030. Diabetes Care, 27, 1047-1053.
[2] Kurniawan, F., Tsakova, V. and Mirsky, V.M. (2006) Gold Nano-particles in Nonenzymatic Electrochemical Detection of Sugars. Electroanalysis, 18, 1937-1942.
[3] Wang, J. (2008) Electrochemical Glucose Biosensors. Chemistry Review, 108, 814.
[4] Wang, Z., Liu, S., Wu, P. and Cai, C. (2009) Detection of Glucose Based on Direct Electron Transfer Reaction of Glucose Oxidase Immobilized on Highly Ordered Polyaniline Nanotubes. Analytical Chemistry, 81, 1638-1645.
[5] Wang, J. and Pamidi, P.V.A. (1997) Sol−Gel-Derived Gold Composite Electrodes. Analytical Chemistry, 69, 4490- 4494.
[6] Salimi, A. and Roushani, M. (2005) Non-Enzymatic Glucose Detection Free of Ascorbic Acid Interference Using Nickel Powder and Nafion Sol–Gel Dispersed Renewable Carbon Ceramic Electrode. Electrochemistry Communications, 7, 879-887.
[7] Meng, L., Jin, J., Yang, G., Lu, T., Zhang, H. and Cai, C. (2009) Nonenzymatic Electrochemical Detection of Glucose Based on Palladium−Single-Walled Carbon Nanotube Hybrid Nanostructures. Analytical Chemistry, 81, 7271-7280.
[8] Song, Y.-Y., Zhang, D., Gao, W. and Xia, X.-H. (2005) Nonenzymatic Glucose Detection by Using a Three-Dimen- sionally Ordered, Macroporous Platinum Template. Chemistry—A Euro-pean Journal, 11, 2177-2182.
[9] Zhang, X., Chan, K.-Y., You, J.-K., Lin, Z.-G. and Tseung, A.C.C. (1997) Partial Oxidation of Glucose by a Pt|WO3 Electrode. Journal of Electroanalytical Chemistry, 430, 147-153.
[10] Yuan, J.H., Wang, K. and Xia, X.H. (2005) Highly Ordered Platinum-Nanotubule Arrays for Amperometric Glucose Sensing. Advanced Functional Materials, 15, 803-809.
[11] Yu, X.-Y., Xu, R.-X., Gao, C., Luo, T., Jia, Y., Liu, J.-H., et al. (2012) Novel 3D Hierarchical Cotton-Candy-Like CuO: Surfactant-Free Solvothermal Synthesis and Application in As(III) Removal. ACS Applied Materials & Interfaces, 4, 1954-1962.
[12] Huang, J., Zhu, Y., Yang, X., Chen, W., Zhou, Y. and Li, C. (2015) Flexible 3D Porous CuO Nanowire Arrays for Enzymeless Glucose Sensing: In Situ Engineered versus Ex Situ Piled. Nanoscale, 7, 559-569.
[13] Xiao, X., Wang, M., Li, H., Pan, Y. and Si, P. (2014) Non-Enzymatic Glucose Sensors Based on Controllable Nanoporous Gold/Copper Oxide Nanohybrids. Talanta, 125, 366-371.
[14] Niu, X., Lan, M., Zhao, H. and Chen, C. (2013) Highly Sensitive and Selective Nonenzymatic Detection of Glucose Using Three-Dimensional Porous Nickel Nanostructures. Analytical Chemistry, 85, 3561-3569.
[15] Zhang, Y., Liu, Y., Su, L., Zhang, Z., Huo, D., Hou, C., et al. (2014) CuO Nanowires Based Sensitive and Selective Non-Enzymatic Glucose Detection. Sensors and Actuators B: Chemical, 191, 86-93.
[16] Sun, S., Zhang, X., Sun, Y., Yang, S., Song, X. and Yang, Z. (2013) Hierarchical CuO Nanoflowers: Water-Required Synthesis and Their Application in a Nonenzymatic Glucose Biosensor. Physical Chemistry Chemical Physics, 15, 10904-10913.