具有对称结构手性氨基酚化合物的合成
Synthesis of Symmetric Chiral Aminophenol Compounds
DOI: 10.12677/JOCR.2017.52017, PDF, HTML, XML, 下载: 1,568  浏览: 4,918  科研立项经费支持
作者: 杜 婷, 张 奎, 赵 松, 黄 艳:新疆大学化学化工学院石油天然气精细化工教育部&自治区重点实验室,新疆 乌鲁木齐;张旭龙:新疆出入境检验检疫局检验检疫技术中心,新疆 乌鲁木齐
关键词: 氨基酚合成单晶Aminophenol Synthesis Monocrystal
摘要: 分别以1,6-己二胺和对苯二胺为原料,与对映体纯L-缬氨酸发生缩合进而得到手性氨基酚化合物。所合成氨基酚及相应的中间产物经过高分辨质谱、核磁共振氢谱和核磁共振碳谱等进行表征并确认结构。此外,化合物2A和7B-1通过X-ray单晶衍射法确定了结构。
Abstract: In this paper, 1,6-hexamethylenediamine and p-phenylenediamine were selected to react respec-tively with commercially available L-valine to obtain the desired symmetrical aminophenol com-pounds. The structures of the aminophenol and the corresponding intermediate were characterized by high resolution mass spectrometry, nuclear magnetic resonance spectroscopy. In addition, a single crystal of compound 2A and 7B-1were obtained by recrystallization, and their structures were determined by x-ray analysis.
文章引用:杜婷, 张奎, 赵松, 张旭龙, 黄艳. 具有对称结构手性氨基酚化合物的合成[J]. 有机化学研究, 2017, 5(2): 128-136. https://doi.org/10.12677/JOCR.2017.52017

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