熊果酸分子印迹聚合物的合成及其特性研究
Synthesis and Evaluation of Molecularly Imprinting Polymer Using Ursolic Acid as Template
DOI: 10.12677/AAC.2017.74028, PDF, HTML, XML, 下载: 1,660  浏览: 3,469  科研立项经费支持
作者: 王建新, 王 佳, 刘勇志, 刘沪东, 刘彩红：泰山医学院药学院，山东 泰安
关键词: 表面分子印迹聚合物；熊果酸；吸附性能；Surface Molecularly Imprinted Polymer； Ursolic Acid； Adsorption Properties
摘要: 采用表面分子印迹技术，以熊果酸(UA)为模板分子，α-甲基丙烯酸(MAA)为功能单体，乙二醇二甲基丙烯酸酯为交联剂，制备熊果酸分子印迹聚合物。通过静态吸附平衡实验、动态吸附实验及选择性吸附实验，考察了分子印迹聚合物的吸附性能，结果显示MIPs表面形成了能与模板分子相匹配且具有特异识别位点的孔穴结构，MIPs对UA具有良好的吸附性能和特异选择识别能力。
Abstract: This study aims to prepare ursolic acid molecularly imprinting polymer (MIPs) by surface polymerization method at the surface of modified silica particles by using ursolic acid (UA) as the template molecule, α-methacrylic acid as functional monomer and ethylene glycol dimethacrylate as the crosslinker. The adsorption and recognition properties of the obtained polymers were eval-uated by static binding test, dynamic binding test and selective binding test. The results showed that MIPs displayed higher recognition ability and adsorption capacity to the template mole-cule-UA.
文章引用：王建新, 王佳, 刘勇志, 刘沪东, 刘彩红. 熊果酸分子印迹聚合物的合成及其特性研究[J]. 分析化学进展, 2017, 7(4): 216-221. https://doi.org/10.12677/AAC.2017.74028

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