[1]
|
Wu, Z., Zeng, Q., Cao, K., et al. (2016) Exosomes: Small Vesicles with Big Roles in Hepatocellular Carcinoma. Oncotarget, 37, 687-697. https://doi.org/10.18632/oncotarget.10807
|
[2]
|
Ibrahim, S.H., Hirsova, P., Tomita, K., et al. (2016) Mixed Lineage Kinase 3 Mediates Release of C-X-C Motif Ligand 10-Bearing Chemotactic Extracellular Vesicles from Lipotoxic Hepatocytes. Hepatology, 63, 731-744.
https://doi.org/10.1002/hep.28252
|
[3]
|
Faure, J., Lachenal, G., Court, M., et al. (2006) Exosomes Are Released by Cultured Cortical Neurones. Molecular and Cellular Neuroscience, 31, 642-648. https://doi.org/10.1016/j.mcn.2005.12.003
|
[4]
|
Han, C., Sun, X., Liu, L., et al. (2016) Exosomes and Their Therapeutic Potentials of Stem Cells. Stem Cells International, 2016, 7653489. https://doi.org/10.1155/2016/7653489
|
[5]
|
Zhou, H., Cheruvanky, A., Hu, X., et al. (2008) Urinary Exosomal Transcription Factors, a New Class of Biomarkers for Renal Disease. Kidney International, 74, 613-621. https://doi.org/10.1038/ki.2008.206
|
[6]
|
Skog, J., Wurdinger, T., van Rijn, S., et al. (2008) Glioblastoma Microvesicles Trans-port RNA and Proteins That Promote Tumour Growth and Provide Diagnostic Biomarkers. Nature Cell Biology, 10, 1470-1476.
https://doi.org/10.1038/ncb1800
|
[7]
|
Li, J.C., Sherman-Baust, A., Tsai-Turton, M., et al. (2009) Claudin-Containing Exosomes in the Peripheral Circulation of Women with Ovarian Cancer. BMC Cancer, 9, 244. https://doi.org/10.1186/1471-2407-9-244
|
[8]
|
Trajkovic, K., Hsu, C., Chiantia, S., et al. (2008) Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes. Science, 319, 1244-1247. https://doi.org/10.1126/science.1153124
|
[9]
|
Theos, A.C., Truschel, S.T., Tenza, D., et al. (2006) A Lumenal Domain-Dependent Pathway for Sorting to Intralumenal Vesicles of Multivesicular Endosomes Involved in Organelle Morphogenesis. Developmental Cell, 10, 343-354.
https://doi.org/10.1016/j.devcel.2006.01.012
|
[10]
|
李维特, 杨硕, 乔蕊, 等. 外泌体的生物学特性及其在分子标记中的作用[J]. 实用医学杂志, 2017(12): 2062-2064.
|
[11]
|
Hyenne, V., Labouesse, M. and Goetz, J.G. (2016) The Small GTPase Ral Orches-trates MVB Biogenesis and Exosome Secretion. Small GTPases, 1-7. https://doi.org/10.1080/21541248.2016.1251378
|
[12]
|
Morelli, A.E., Larregina, A.T., Shufesky, W.J., et al. (2004) Endocytosis, Intracellular Sorting, and Processing of Exosomes by Dendritic Cells. Blood, 104, 3257-3266. https://doi.org/10.1182/blood-2004-03-0824
|
[13]
|
Salimu, J., Webber, J., Gurney, M., et al. (2017) Dominant Immunosuppres-sion of Dendritic Cell Function by Prostate-Cancer-Derived Exosomes. Journal of Extracellular Vesicles, 6, 1368823.
https://doi.org/10.1080/20013078.2017.1368823
|
[14]
|
Vlassov, A.V., Magdaleno, S., Setterquist, R., et al. (2012) Exosomes: Current Knowledge of Their Composition, Biological Functions, and Diagnostic and Therapeutic Potentials. Biochimica et Biophysica Acta, 1820, 940-948.
https://doi.org/10.1016/j.bbagen.2012.03.017
|
[15]
|
Yu, S., Cao, H., Shen, B., et al. (2015) Tumor-Derived Exosomes in Cancer Progression and Treatment Failure. Oncotarget, 6, 37151-37168. https://doi.org/10.18632/oncotarget.6022
|
[16]
|
Tang, X.J., Sun, X.Y., Huang, K.M., et al. (2015) Therapeutic Potential of CAR-T Cell-Derived Exosomes: A Cell-Free Modality for Targeted Cancer Therapy. Oncotarget, 6, 44179-44190.
https://doi.org/10.18632/oncotarget.6175
|
[17]
|
郭静, 徐桂英, 黄昊, 等. 外泌体在肿瘤诊疗中的研究进展[J]. 中国比较医学杂志, 2017(2): 86-92.
|
[18]
|
Kogure, T., Lin, W.L., Yan, I.K., et al. (2011) Intercellular Nanovesicle-Mediated microRNA Transfer: A Mechanism of Environmental Modulation of Hepatocellular Cancer Cell Growth. Hepatology, 54, 1237-1248.
https://doi.org/10.1002/hep.24504
|
[19]
|
Tu, T., Budzinska, M.A., Maczurek, A.E., et al. (2014) Novel Aspects of the Liver Mi-croenvironment in Hepatocellular Carcinoma Pathogenesis and Development. International Journal of Molecular Sciences, 15, 9422-9458.
https://doi.org/10.3390/ijms15069422
|
[20]
|
Van Zijl, F., Krupitza, G. and Mikulits, W. (2011) Initial Steps of Metastasis: Cell Invasion and Endothelial Transmigration. Mutation Research, 728, 23-34. https://doi.org/10.1016/j.mrrev.2011.05.002
|
[21]
|
Kahlert, C. and Kalluri, R. (2013) Exosomes in Tumor Microenvironment Influence Cancer Progression and Metastasis. Journal of Molecular Medicine, 91, 431-437. https://doi.org/10.1007/s00109-013-1020-6
|
[22]
|
Balamurugan, K. (2016) HIF-1 at the Crossroads of Hypoxia, Inflammation, and Cancer. International Journal of Cancer, 138, 1058-1066. https://doi.org/10.1002/ijc.29519
|
[23]
|
Yao, H., Liu, N., Lin, M.C., et al. (2016) Positive Feedback Loop between Cancer Stem Cells and Angiogenesis in Hepatocellular Carcinoma. Cancer Letters, 379, 213-219. https://doi.org/10.1016/j.canlet.2016.03.014
|
[24]
|
Zhang, N., Duan, W.D., Leng, J.J., et al. (2015) STAT3 Regulates the Migration and Invasion of a Stemlike Subpopulation through microRNA21 and Multiple Targets in Hepatocellular Carcinoma. Oncology Reports, 33, 1493-1498.
https://doi.org/10.3892/or.2015.3710
|
[25]
|
Wei, J.X., Lv, L.H., Wan, Y.L., et al. (2015) Vps4A Functions as a Tumor Suppressor by Regulating the Secretion and Uptake of Exosomal microRNAs in Human Hepatoma Cells. Hepatology, 61, 1284-1294.
https://doi.org/10.1002/hep.27660
|
[26]
|
He, M., Qin, H., Poon, T.C., et al. (2015) Hepatocellular Carcinoma-Derived Exosomes Promote Motility of Immortalized Hepatocyte through Transfer of Oncogenic Proteins and RNAs. Carcinogenesis, 36, 1008-1018.
https://doi.org/10.1093/carcin/bgv081
|
[27]
|
Huang, A., Dong, J., Li, S., et al. (2015) Exosomal Transfer of Vasorin Expressed in Hepatocellular Carcinoma Cells Promotes Migration of Human Umbilical Vein Endothelial Cells. International Journal of Biological Sciences, 11, 961-969. https://doi.org/10.7150/ijbs.11943
|
[28]
|
Pegtel, D.M., Cosmopoulos, K., Thorley-Lawson, D.A., et al. (2010) Functional Delivery of Viral miRNAs via Exosomes. Proceedings of the National Academy of Sciences, 107, 6328-6233. https://doi.org/10.1073/pnas.0914843107
|
[29]
|
Lenassi, M., Cagney, G., Liao, M., et al. (2010) HIV Nef Is Secreted in Exosomes and Triggers Apoptosis in Bystander CD4+ T Cells. Traffic, 11, 110-122. https://doi.org/10.1111/j.1600-0854.2009.01006.x
|
[30]
|
Feng, Z., Hensley, L., McKnight, K.L., et al. (2013) A Pathogenic Pi-cornavirus Acquires an Envelope by Hijacking Cellular Membranes. Nature, 496, 367-371. https://doi.org/10.1038/nature12029
|
[31]
|
Lv, L.H., Wan, Y.L., Lin, Y., et al. (2012) Anticancer Drugs Cause Release of Ex-osomes with Heat Shock Proteins from Human Hepatocellular Carcinoma Cells That Elicit Effective Natural Killer Cell Antitumor Responses in Vitro. The Journal of Biological Chemistry, 287, 15874-15885. https://doi.org/10.1074/jbc.M112.340588
|
[32]
|
Ko, S.F., Yip, H.K., Zhen, Y.Y., et al. (2015) Adipose-Derived Mesenchymal Stem Cell Exosomes Suppress Hepatocellular Carcinoma Growth in a Rat Model: Apparent Diffusion Coefficient, Natural Killer T-Cell Responses, and Histopathological Features. Stem Cells International, 2015, Article ID: 853506. https://doi.org/10.1155/2015/853506
|
[33]
|
Wang, H., Hou, L., Li, A., et al. (2014) Ex-pression of Serum Exosomal microRNA-21 in Human Hepatocellular Carcinoma. BioMed Research International, 2014, Article ID: 864894.
|
[34]
|
Sohn, W., Kim, J., Kang, S.H., et al. (2015) Serum Exosomal microRNAs as Novel Biomarkers for Hepatocellular Carcinoma. Experimental & Molecular Medicine, 47, e184. https://doi.org/10.1038/emm.2015.68
|
[35]
|
Liu, W., Hu, J., Zhou, K., et al. (2017) Serum Exosomal miR-125b Is a Novel Prognostic Marker for Hepatocellular Carcinoma. OncoTargets and Therapy, 10, 3843-3851. https://doi.org/10.2147/OTT.S140062
|
[36]
|
Sugimachi, K., Matsumura, T., Hirata, H., et al. (2015) Identification of a Bona Fide microRNA Biomarker in Serum Exosomes That Predicts Hepatocellular Carcinoma Recurrence after Liver Transplantation. British Journal of Cancer, 112, 532-538. https://doi.org/10.1038/bjc.2014.621
|
[37]
|
Lener, T., Gimona, M., Aigner, L., et al. (2015) Applying Extracellular Vesicles Based Therapeutics in Clinical Trials—An ISEV Position Paper. Journal of Extracellular Vesicles, 4, 30087. https://doi.org/10.3402/jev.v4.30087
|
[38]
|
Tian, Y., Li, S., Song, J., et al. (2014) A Doxorubicin Delivery Platform using Engineered Natural Membrane Vesicle Exosomes for Targeted Tumor Therapy. Biomaterials, 35, 2383-2390.
https://doi.org/10.1016/j.biomaterials.2013.11.083
|
[39]
|
Kooijmans, S.A., Aleza, C.G., Roffler, S.R., et al. (2016) Display of GPI-Anchored anti-EGFR Nanobodies on Extracellular Vesicles Promotes Tumour Cell Targeting. Journal of Extracellular Vesicles, 5, 31053.
https://doi.org/10.3402/jev.v5.31053
|
[40]
|
Villarroya-Beltri, C., Gutierrez-Vazquez, C., Sanchez-Cabo, F., et al. (2013) Sumoy-lated hnRNPA2B1 Controls the Sorting of miRNAs into Exosomes through Binding to Specific Motifs. Nature Communications, 4, 2980.
https://doi.org/10.1038/ncomms3980
|
[41]
|
Santangelo, L., Giurato, G., Cicchini, C., et al. (2016) The RNA-Binding Protein SYNCRIP Is a Component of the Hepatocyte Exosomal Machinery Controlling MicroRNA Sorting. Cell Reports, 17, 799-808.
https://doi.org/10.1016/j.celrep.2016.09.031
|
[42]
|
Takahashi, K., Yan, I.K., Kogure, T., et al. (2014) Extracellular Ve-sicle-Mediated Transfer of Long Non-Coding RNA ROR Modulates Chemosensitivity in Human Hepatocellular Cancer. FEBS Open Bio, 4, 458-467.
https://doi.org/10.1016/j.fob.2014.04.007
|
[43]
|
Qu, Z., Wu, J., Wu, J., et al. (2016) Exosomes Derived from HCC Cells Induce Sorafenib Resistance in Hepatocellular Carcinoma both in Vivo and in Vitro. Journal of Experimental & Clinical Cancer Research, 35, 159.
https://doi.org/10.1186/s13046-016-0430-z
|