DCD肝移植供肝质量评估进展文献综述
The Literature Review of Progress in Quality Assessment for Donation-after-Cardiac-Death Liver Transplantation
DOI: 10.12677/ACM.2018.82043, PDF,   
作者: 司铮先, 刘宝志, 陈永林, 张升宁:昆明医科大学附属甘美医院肝胆胰一科,云南 昆明;冯婧星:昆明医科大学第二附属医院肝胆胰二科,云南 昆明
关键词: DCD肝移植DCD供肝质量脂肪肝冷–热缺血时间危险因素Donation-after-Cardiac-Death Liver Transplantation Quality of DCD Liver Liver Steatosis Cold-Warm Ischemia Time Risk Factors
摘要: 1963年美国医师Starzl实施了全球首例人体原位肝移植手术,此后随着肝移植外科技术的改进、免疫抑制方案的优化以及移植后病人管理的进步,肝移植成为终末期肝病的最佳治疗手段。然而供肝资源短缺制约了肝移植的进一步发展。近年来心脏死亡器官捐献(DCD)供肝在肝移植手术中的应用,有效扩大了供肝池,并已经得到世界卫生组织认可在全世界范围内实行。DCD供肝作为扩大选择标准的供肝来源,准确评估其质量并确保移植后受体的生存率,是国内外器官移植领域的研究热点。本文就DCD供肝质量评估最新进展作一综述。
Abstract: The American surgeon Thomas Starzl performed the first human liver transplantation surgery in human history in 1963. Then improvements in surgical techniques, immunosuppression, and post-transplantation patient care have led to the optimization of liver transplantation outcomes. However, the scarcity of donor liver restricts further development of liver transplantation. In recent years, the use of donation after cardiac death (DCD) liver effectively expands the donor pool and has been accepted by the WHO. There are so many researches focusing on how to effectively assess the quality of DCD liver in order to ensure the survival rate after transplantation. The present essay reviews the latest developments in this field.
文章引用:司铮先, 冯婧星, 刘宝志, 陈永林, 张升宁. DCD肝移植供肝质量评估进展文献综述[J]. 临床医学进展, 2018, 8(2): 253-258. https://doi.org/10.12677/ACM.2018.82043

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