正电子发射型计算机断层显像CT (PET-CT)避免漏诊眼睑恶性肿瘤伴全身转移一例
A Case of Positron Emission Tomography-Computed Tomography (PET-CT) to Avoid Missed Diagnosis of a Malignant Eyelid Tumor with Systemic Metastasis
DOI: 10.12677/HJO.2018.73020, PDF,   
作者: 唐 飞:四川大学华西医院上锦南府医院眼科,四川 成都;甘 露:中航工业成都363医院眼科,四川 成都;晋丝雨:四川大学华西医院上锦南府医院门诊,四川 成都;何为民*:四川大学华西医院眼科,四川 成都
关键词: PET-CT眼睑肿物全身转移PET-CT Eyelid Mass Metastasis
摘要: 患者赵某,女,50岁2月,因“右眼发现‘包块’3月,术后2月复发”,于就诊前3月发现眼睑“包块”,2月前在当地医院行“麦粒肿切除术”。术后口服“消炎药”。术后2周,自觉右眼“包块复发,迅速长大”,到我院就诊后行正电子发射型计算机断层显像CT (PET-CT)检查,检查结果:右眼眼睑和肺部均有恶性占位。遂安排行“右眼眼睑肿物切除+皮瓣转位术”,病理检查结果显示:恶性黑色素瘤(梭A细胞型)。随访6月,肿瘤未见复发及转移。
Abstract: The patient, Miss Zhao, female, 50 years old, was found a tumor in the right eye in 3 month and re-lapsed in 2 month after surgery. She discovered the eyelid “bag block” after three month before going to the doctor. Before two month, she was diagnosed hordeolum in the local hospital, then she took orally anti-inflammatory drug after surgery. After 2 weeks after surgery, consciously the right eye “bag block recurred and grew up quickly”, she went to our hospital for treatment, and the positron emission computed tomography (PET-CT) was examined. The results show that the right eye eyelid and the lungs had malignant position. Then the “Right eye eyelid mass resection + flap transposition” are arranged; pathological examination results show malignant melanoma (shuttle A cell type). There was no recurrence or metastasis of tumor after 6 month follow-up visit.
文章引用:唐飞, 甘露, 晋丝雨, 何为民. 正电子发射型计算机断层显像CT (PET-CT)避免漏诊眼睑恶性肿瘤伴全身转移一例[J]. 眼科学, 2018, 7(3): 133-138. https://doi.org/10.12677/HJO.2018.73020

参考文献

[1] 吴星, 宋志刚, 王兆艳. 眼睑肿物临床病理分析763例[J]. 眼科新进展, 2014, 34(8): 738-740.
[2] 张帆, 吴晓梅. 眼睑皮肤恶性黑色素瘤早期检测进展[J]. 国际眼科杂志, 2007, 7(2): 493-495. http://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFD&dbname=cjfd2007&filename=GJYK200702062&uid= WEEvREcwSlJHSldRa1FhcTdWajFuQ2FSMWRpbDZXYmt2ZVlSdmtOQjJ2RT0=$9A4hF_YAuvQ5obgVAqNKPCYcEjKensW4ggI8Fm 4gTkoUKaID8j8gFw!!&v=MzE2NjhaT1JxRnlubFViL01JaWZTWmJHNEh0Yk1yWTlEWm9SOGVYMUx1eFlTN0RoMVQzcVRyV00xRn JDVVJMS2Y=
[3] 李凤鸣. 中华眼科学[M]. 第2版. 北京: 人民卫生出版社, 2005: 882-884.
[4] Weber, J.L., Smalley, K.S., Sondak, V.K., et al. (2013) Conjunctival Melanomas Harbor BRAF and NRAS Mutations—Letter. Clinical Cancer Research, 19, 6329-6330.
[Google Scholar] [CrossRef
[5] Harbour, J.W. (2016) Uveal and Conjunctival Melanoma: Close Together-But Only Distantly Related. Oncology, 30, 44 + 48.
[6] Yin, V.T., Warneke, C.L., Merritt, H.A., et al. (2014) Number of Excisions Required to Obtain Clear Surgical Margins and Prognostic Value of AJCC T Category for Patients with Eyelid Melanoma. British Journal of Ophthalmology, 98, 1681-1685.
[Google Scholar] [CrossRef] [PubMed]
[7] Harish, V., Bond, J.S., Scolyer, R.A., et al. (2013) Margins of Excision and Prognostic Factors for Cutaneous Eyelid Melanomas. Journal of Plastic, Reconstructive & Aesthetic Surgery, 66, 1066-1073.
[Google Scholar] [CrossRef] [PubMed]
[8] 孙涛, 韩善清, 汪家旺. PET/CT 成像原理、优势及临床应用[J]. 中国医学物理学杂志, 2010, 27, 1581-1582. http://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFQ&dbname=CJFD2010&filename=YXWZ201001005&v=MDIwMzlMUERYY2RMRzRIOUhNcm85RllZUjhlWDFMdXhZUzdEaDFUM3FUcldNMUZyQ1VSTEtmWk9ScUZ5bmhVTC8=
[9] 陈雄. PET、CT 成像原理、优势及临床应用[J]. 医药前沿, 2015, 5(6): 378-380.
[10] 房娜, 王艳丽, 曾磊, 等. 18F-FDG PET/CT在健康体检中发现恶性肿瘤的价值[J]. 齐鲁医学杂志, 2012, 27(1): 19-21. http://kreader.cnki.net/Kreader/CatalogViewPage.aspx?dbCode=CJFQ&filename=SPAN201201008&tablename=CJFD2012&compose=&first=1&uid=
[11] Kubota, K., Okasaki, M., Minamimoto, R., et al. (2014) Lesion-Based Analysis of (18) F-FDG Uptake and (111) In-Pentetreotide Uptake by Neuroendocrine Tumors. Annals of Nuclear Medicine, 28, 1004.
[Google Scholar] [CrossRef] [PubMed]
[12] Binderup, T., Knigge, U., Loft, A., et al. (2010) 18F-Fluorodeoxyglucose Positron Emission Tomography Predicts Survival of Patients with Neuroendocrine Tumors. Clinical Cancer Research, 16, 978.
[Google Scholar] [CrossRef
[13] Gupta, N.C., Tamim, W.J., Graeber, G.G., et al. (2001) Mediastinal Lymph Node Sampling Following Positron Emission Tomography with Fluorodeoxyglucose Imaging in Lung Cancer staging. Chest, 120, 521-527.
[Google Scholar] [CrossRef] [PubMed]
[14] Cerfolio, R.J., Bryant, A.S., Ohja, B., et al. (2005) The Maximum Standardized Uptake Values on Positron Emission Tomography of a Non-Small Cell Lung Cancer Predict Stage, Recurrence, and Survival. Journal of Thoracic and Cardiovascular Surgery, 130, 151-159.
[Google Scholar] [CrossRef] [PubMed]
[15] Huang, Y.Y., Liang, W.Y., Tsai, C.C., et al. (2015) Comparison of the Clinical Characteristics and Outcome of Benign and Malignant Eyelid Tumors: An Analysis of 4521 Eyelid Tumors in a Tertiary Medical Center. BioMed Research International, 2015, Article ID: 453091.
[Google Scholar] [CrossRef] [PubMed]